[English] 日本語
Yorodumi
- EMDB-47091: Taeniopygia guttata R2 retrotransposon (R2Tg) initiating target-p... -

+
Open data


ID or keywords:

Loading...

-
Basic information

Entry
Database: EMDB / ID: EMD-47091
TitleTaeniopygia guttata R2 retrotransposon (R2Tg) initiating target-primed reverse transcription
Map dataSharpened map of Taeniopygia guttata R2 retrotransposon initiating target-primed reverse transcription
Sample
  • Complex: Taeniopygia guttata R2 retrotransposon initiating target-primed reverse transcription
    • Protein or peptide: R2Tg retrotransposon ORF
    • DNA: 28S DNA bottom strand, 3' side
    • DNA: 28S DNA bottom strand, 5' side (priming strand)
    • RNA: R2Tg 3'UTR RNA
    • DNA: 28S DNA top strand
  • Ligand: MAGNESIUM ION
  • Ligand: THYMIDINE-5'-TRIPHOSPHATE
  • Ligand: ZINC ION
Keywordsretrotransposon / LINE / reverse transcriptase / endonuclease / RNA BINDING PROTEIN-RNA-DNA complex
Biological speciesTaeniopygia guttata (zebra finch)
Methodsingle particle reconstruction / cryo EM / Resolution: 3.2 Å
AuthorsWilkinson ME / Edmonds KHK / Zhang F
Funding support United States, 1 items
OrganizationGrant numberCountry
Howard Hughes Medical Institute (HHMI) United States
CitationJournal: Nat Commun / Year: 2025
Title: Structure and biochemistry-guided engineering of an all-RNA system for DNA insertion with R2 retrotransposons.
Authors: KeHuan K Edmonds / Max E Wilkinson / Daniel Strebinger / Hongyu Chen / Blake Lash / Clarissa C Schaefer / Shiyou Zhu / Dangliang Liu / Shai Zilberzwige-Tal / Alim Ladha / Michelle L Walsh / ...Authors: KeHuan K Edmonds / Max E Wilkinson / Daniel Strebinger / Hongyu Chen / Blake Lash / Clarissa C Schaefer / Shiyou Zhu / Dangliang Liu / Shai Zilberzwige-Tal / Alim Ladha / Michelle L Walsh / Chris J Frangieh / Nicholas A Vaz Reay / Rhiannon K Macrae / Xiao Wang / Feng Zhang /
Abstract: R2 elements, a class of non-long terminal repeat (non-LTR) retrotransposons, have the potential to be harnessed for transgene insertion. However, efforts to achieve this are limited by our ...R2 elements, a class of non-long terminal repeat (non-LTR) retrotransposons, have the potential to be harnessed for transgene insertion. However, efforts to achieve this are limited by our understanding of the retrotransposon mechanisms. Here, we structurally and biochemically characterize R2 from Taeniopygia guttata (R2Tg). We show that R2Tg cleaves both strands of its ribosomal DNA target and binds a pseudoknotted RNA element within the R2 3' UTR to initiate target-primed reverse transcription. Guided by these insights, we engineer and characterize an all-RNA system for transgene insertion. We substantially reduce the system's size and insertion scars by eliminating unnecessary R2 sequences on the donor. We further improve the integration efficiency by chemically modifying the 5' end of the donor RNA and optimizing delivery, creating a compact system that achieves over 80% integration efficiency in several human cell lines. This work expands the genome engineering toolbox and provides mechanistic insights that will facilitate future development of R2-mediated gene insertion tools.
History
DepositionSep 19, 2024-
Header (metadata) releaseMay 21, 2025-
Map releaseMay 21, 2025-
UpdateJul 16, 2025-
Current statusJul 16, 2025Processing site: RCSB / Status: Released

-
Structure visualization

Supplemental images

emd_47091.png

Downloads & links

-
Map

FileDownload / File: emd_47091.map.gz / Format: CCP4 / Size: 91.1 MB / Type: IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)
AnnotationSharpened map of Taeniopygia guttata R2 retrotransposon initiating target-primed reverse transcription
Projections & slices

Image control

Size
Brightness
Contrast
Others
AxesZ (Sec.)Y (Row.)X (Col.)
0.92 Å/pix.
x 288 pix.
= 265.19 Å		0.92 Å/pix.
x 288 pix.
= 265.19 Å		0.92 Å/pix.
x 288 pix.
= 265.19 Å

Surface

Projections

Slices (1/3)

Slices (1/2)

Slices (2/3)

Images are generated by Spider.

Voxel sizeX=Y=Z: 0.9208 Å
Density

Histogram

Histogram (log scale)
Contour LevelBy AUTHOR: 0.02
Minimum - Maximum-0.049436692 - 0.09317815
Average (Standard dev.)-0.00010939993 (±0.003444031)
SymmetrySpace group: 1
Details

EMDB XML:

Map geometry
Axis orderXYZ
Origin000
Dimensions288288288
Spacing288288288
CellA=B=C: 265.1904 Å
α=β=γ: 90.0 °

-
Supplemental data

-
Mask #1

Fileemd_47091_msk_1.map
Projections & Slices
AxesZYX

Projections

Slices (1/2)
Density Histograms

Histogram

Histogram (log scale)

-
Half map: Half-map 2 of Taeniopygia guttata R2 retrotransposon initiating...

Fileemd_47091_half_map_1.map
AnnotationHalf-map 2 of Taeniopygia guttata R2 retrotransposon initiating target-primed reverse transcription
Projections & Slices
AxesZYX

Projections

Slices (1/2)
Density Histograms

Histogram

Histogram (log scale)

-
Half map: Half-map 1 of Taeniopygia guttata R2 retrotransposon initiating...

Fileemd_47091_half_map_2.map
AnnotationHalf-map 1 of Taeniopygia guttata R2 retrotransposon initiating target-primed reverse transcription
Projections & Slices
AxesZYX

Projections

Slices (1/2)
Density Histograms

Histogram

Histogram (log scale)

-
Sample components

-
Entire : Taeniopygia guttata R2 retrotransposon initiating target-primed r...

EntireName: Taeniopygia guttata R2 retrotransposon initiating target-primed reverse transcription
Components
  • Complex: Taeniopygia guttata R2 retrotransposon initiating target-primed reverse transcription
    • Protein or peptide: R2Tg retrotransposon ORF
    • DNA: 28S DNA bottom strand, 3' side
    • DNA: 28S DNA bottom strand, 5' side (priming strand)
    • RNA: R2Tg 3'UTR RNA
    • DNA: 28S DNA top strand
  • Ligand: MAGNESIUM ION
  • Ligand: THYMIDINE-5'-TRIPHOSPHATE
  • Ligand: ZINC ION

-
Supramolecule #1: Taeniopygia guttata R2 retrotransposon initiating target-primed r...

SupramoleculeName: Taeniopygia guttata R2 retrotransposon initiating target-primed reverse transcription
type: complex / ID: 1 / Parent: 0 / Macromolecule list: #1-#5
Source (natural)Organism: Taeniopygia guttata (zebra finch)
Molecular weightTheoretical: 380 KDa

-
Macromolecule #1: R2Tg retrotransposon ORF

MacromoleculeName: R2Tg retrotransposon ORF / type: protein_or_peptide / ID: 1 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Taeniopygia guttata (zebra finch)
Molecular weightTheoretical: 157.228484 KDa
Recombinant expressionOrganism: Saccharomyces cerevisiae (brewer's yeast)
SequenceString: MASCPKPGPP VSAGAMSLES GLTTHSVLAI ERGPNSLANS GSDFGGGGLG LPLRLLRVSV GTQTSRSDWV DLVSWSHPGP TSKSQQVDL VSLFPKHRVD LLSKNDQVDL VAQFLPSKFP PNLAENDLAL LVNLEFYRSD LHVYECVHFA AHWEGLSGLP E VYEQLAPQ ...String:
MASCPKPGPP VSAGAMSLES GLTTHSVLAI ERGPNSLANS GSDFGGGGLG LPLRLLRVSV GTQTSRSDWV DLVSWSHPGP TSKSQQVDL VSLFPKHRVD LLSKNDQVDL VAQFLPSKFP PNLAENDLAL LVNLEFYRSD LHVYECVHFA AHWEGLSGLP E VYEQLAPQ PCVGETLHSS LPRDSELFVP EEGSSEKESE DAPKTSPPTP GKHGLEQTGE EKVMVTVPDK NPPCPCCGTR VN SVLNLIE HLKVSHGKRG VCFRCAKCGK ENSNYHSVVC HFPKCRGPET EKAPAGEWIC EVCNRDFTTK IGLGQHKRLA HPA VRNQER IVASQPKETS NRGAHKRCWT KEEEELLIRL EAQFEGNKNI NKLIAEHITT KTAKQISDKR RLLSRKPAEE PREE PGTCH HTRRAAASLR TEPEMSHHAQ AEDRDNGPGR RPLPGRAAAG GRTMDEIRRH PDKGNGQQRP TKQKSEEQLQ AYYKK TLEE RLSAGALNTF PRAFKQVMEG RDIKLVINQT AQDCFGCLES ISQIRTATRD KKDTVTREKH PKKPFQKWMK DRAIKK GNY LRFQRLFYLD RGKLAKIILD DIECLSCDIP LSEIYSVFKT RWETTGSFKS LGDFKTYGKA DNTAFRELIT AKEIEKN VQ EMSKGSAPGP DGITLGDVVK MDPEFSRTME IFNLWLTTGK IPDMVRGCRT VLIPKSSKPD RLKDINNWRP ITIGSILL R LFSRIVTARL SKACPLNPRQ RGFIRAAGCS ENLKLLQTII WSAKREHRPL GVVFVDIAKA FDTVSHQHII HALQQREVD PHIVGLVSNM YENISTYITT KRNTHTDKIQ IRVGVKQGDP MSPLLFNLAM DPLLCKLEES GKGYHRGQSS ITAMAFADDL VLLSDSWEN MNTNISILET FCNLTGLKTQ GQKCHGFYIK PTKDSYTIND CAAWTINGTP LNMIDPGESE KYLGLQFDPW I GIARSGLS TKLDFWLQRI DQAPLKPLQK TDILKTYTIP RLIYIADHSE VKTALLETLD QKIRTAVKEW LHLPPCTCDA IL YSSTRDG GLGITKLAGL IPSVQARRLH RIAQSSDDTM KCFMEKEKME QLHKKLWIQA GGDRENIPSI WEAPPSSEPP NNV STNSEW EAPTQKDKFP KPCNWRKNEF KKWTKLASQG RGIVNFERDK ISNHWIQYYR RIPHRKLLTA LQLRANVYPT REFL ARGRQ DQYIKACRHC DADIESCAHI IGNCPVTQDA RIKRHNYICE LLLEEAKKKD WVVFKEPHIR DSNKELYKPD LIFVK DARA LVVDVTVRYE AAKSSLEEAA AEKVRKYKHL ETEVRHLTNA KDVTFVGFPL GARGKWHQDN FKLLTELGLS KSRQVK MAE TFSTVALFSS VDIVHMFASR ARKSMVM

-
Macromolecule #2: 28S DNA bottom strand, 3' side

MacromoleculeName: 28S DNA bottom strand, 3' side / type: dna / ID: 2 / Number of copies: 1 / Classification: DNA
Source (natural)Organism: Taeniopygia guttata (zebra finch)
Molecular weightTheoretical: 65.051477 KDa
SequenceString: (DT)(DT)(DC)(DC)(DC)(DT)(DT)(DG)(DG)(DC) (DT)(DG)(DT)(DG)(DG)(DT)(DT)(DT)(DC)(DG) (DC)(DT)(DA)(DG)(DA)(DT)(DA)(DG)(DT) (DA)(DG)(DA)(DT)(DA)(DG)(DG)(DG)(DA)(DC) (DA) (DG)(DT)(DG)(DG)(DG)(DA) ...String:
(DT)(DT)(DC)(DC)(DC)(DT)(DT)(DG)(DG)(DC) (DT)(DG)(DT)(DG)(DG)(DT)(DT)(DT)(DC)(DG) (DC)(DT)(DA)(DG)(DA)(DT)(DA)(DG)(DT) (DA)(DG)(DA)(DT)(DA)(DG)(DG)(DG)(DA)(DC) (DA) (DG)(DT)(DG)(DG)(DG)(DA)(DA)(DT) (DC)(DT)(DC)(DG)(DT)(DT)(DA)(DA)(DT)(DC) (DC)(DA) (DT)(DT)(DC)(DA)(DT)(DG)(DC) (DG)(DC)(DG)(DT)(DC)(DA)(DC)(DT)(DA)(DA) (DT)(DT)(DA) (DG)(DA)(DT)(DG)(DA)(DC) (DG)(DA)(DG)(DG)(DC)(DA)(DT)(DT)(DT)(DG) (DG)(DC)(DT)(DA) (DC)(DC)(DT)(DT)(DA) (DA)(DG)(DA)(DG)(DA)(DG)(DT)(DC)(DA)(DT) (DA)(DG)(DT)(DT)(DA) (DC)(DT)(DC)(DC) (DC)(DG)(DC)(DC)(DG)(DT)(DT)(DT)(DA)(DC) (DC)(DC)(DG)(DC)(DG)(DC) (DT)(DT)(DC) (DA)(DT)(DT)(DG)(DA)(DA)(DT)(DT)(DT)(DC) (DT)(DT)(DC)(DA)(DC)(DT)(DT) (DT)(DG) (DA)(DC)(DA)(DT)(DT)(DC)(DA)(DG)(DA)(DG) (DC)(DA)(DC)(DT)(DG)(DG)(DG)(DC) (DA) (DG)(DA)(DA)(DA)(DT)(DC)(DA)(DC)(DA)(DT) (DC)(DG)(DC)(DG)(DT)(DC)(DA)(DA)(DC) (DC)(DA)(DG)(DC)(DT)(DG)(DA)(DA)(DA)(DA) (DA)

-
Macromolecule #3: 28S DNA bottom strand, 5' side (priming strand)

MacromoleculeName: 28S DNA bottom strand, 5' side (priming strand) / type: dna / ID: 3 / Number of copies: 1 / Classification: DNA
Source (natural)Organism: Taeniopygia guttata (zebra finch)
Molecular weightTheoretical: 3.997607 KDa
SequenceString:
(DG)(DG)(DC)(DA)(DT)(DT)(DT)(DG)(DG)(DC) (DT)(DA)(DT)

-
Macromolecule #5: 28S DNA top strand

MacromoleculeName: 28S DNA top strand / type: dna / ID: 5 / Number of copies: 1 / Classification: DNA
Source (natural)Organism: Taeniopygia guttata (zebra finch)
Molecular weightTheoretical: 65.225641 KDa
SequenceString: (DT)(DT)(DT)(DT)(DT)(DC)(DA)(DG)(DC)(DT) (DG)(DG)(DT)(DT)(DG)(DA)(DC)(DG)(DC)(DG) (DA)(DT)(DG)(DT)(DG)(DA)(DT)(DT)(DT) (DC)(DT)(DG)(DC)(DC)(DC)(DA)(DG)(DT)(DG) (DC) (DT)(DC)(DT)(DG)(DA)(DA) ...String:
(DT)(DT)(DT)(DT)(DT)(DC)(DA)(DG)(DC)(DT) (DG)(DG)(DT)(DT)(DG)(DA)(DC)(DG)(DC)(DG) (DA)(DT)(DG)(DT)(DG)(DA)(DT)(DT)(DT) (DC)(DT)(DG)(DC)(DC)(DC)(DA)(DG)(DT)(DG) (DC) (DT)(DC)(DT)(DG)(DA)(DA)(DT)(DG) (DT)(DC)(DA)(DA)(DA)(DG)(DT)(DG)(DA)(DA) (DG)(DA) (DA)(DA)(DT)(DT)(DC)(DA)(DA) (DT)(DG)(DA)(DA)(DG)(DC)(DG)(DC)(DG)(DG) (DG)(DT)(DA) (DA)(DA)(DC)(DG)(DG)(DC) (DG)(DG)(DG)(DA)(DG)(DT)(DA)(DA)(DC)(DT) (DA)(DT)(DG)(DA) (DC)(DT)(DC)(DT)(DC) (DT)(DT)(DA)(DA)(DG)(DG)(DT)(DA)(DG)(DC) (DC)(DA)(DA)(DA)(DT) (DG)(DC)(DC)(DT) (DC)(DG)(DT)(DC)(DA)(DT)(DC)(DT)(DA)(DA) (DT)(DT)(DA)(DG)(DT)(DG) (DA)(DC)(DG) (DC)(DG)(DC)(DA)(DT)(DG)(DA)(DA)(DT)(DG) (DG)(DA)(DT)(DT)(DA)(DA)(DC) (DG)(DA) (DG)(DA)(DT)(DT)(DC)(DC)(DC)(DA)(DC)(DT) (DG)(DT)(DC)(DC)(DC)(DT)(DA)(DT) (DC) (DT)(DA)(DC)(DT)(DA)(DT)(DC)(DT)(DA)(DG) (DC)(DG)(DA)(DA)(DA)(DC)(DC)(DA)(DC) (DA)(DG)(DC)(DC)(DA)(DA)(DG)(DG)(DG)(DA) (DA)

-
Macromolecule #4: R2Tg 3'UTR RNA

MacromoleculeName: R2Tg 3'UTR RNA / type: rna / ID: 4 / Number of copies: 1
Source (natural)Organism: Taeniopygia guttata (zebra finch)
Molecular weightTheoretical: 106.656273 KDa
SequenceString: UUCAGGUUAU UUAGAUGCUU AGUUUUUGUA CCUUUCUUGU UUUGUUUAGG AUUUUGAUAG UGUUAGUAUU UUUAUAUUUU UGUACGAUU GCAUAAUGUU CUUUUUUAUA CAGUUCUGUU UUAAUAAAAU AGACGAUAGC UAGAGACGUU AGGGCAGCCA C AAGCCAGU ...String:
UUCAGGUUAU UUAGAUGCUU AGUUUUUGUA CCUUUCUUGU UUUGUUUAGG AUUUUGAUAG UGUUAGUAUU UUUAUAUUUU UGUACGAUU GCAUAAUGUU CUUUUUUAUA CAGUUCUGUU UUAAUAAAAU AGACGAUAGC UAGAGACGUU AGGGCAGCCA C AAGCCAGU UAGGUAGCGG AUAGUAGGUA GGAACAGACU UUUACUAUUU CAUAACGCGU CAAUUACCAC CUGAUUUGGA CC AAUUCAC GGGAUUUGUC CAAGGUGGAC GGGCCACCUU UACUUAACCC GGAAAAGGAA CAUAUAUAAU UUAUGUGUGU UCG AUAAAU AGCCAAA

-
Macromolecule #6: MAGNESIUM ION

MacromoleculeName: MAGNESIUM ION / type: ligand / ID: 6 / Number of copies: 1 / Formula: MG
Molecular weightTheoretical: 24.305 Da

-
Macromolecule #7: THYMIDINE-5'-TRIPHOSPHATE

MacromoleculeName: THYMIDINE-5'-TRIPHOSPHATE / type: ligand / ID: 7 / Number of copies: 1 / Formula: TTP
Molecular weightTheoretical: 482.168 Da
Chemical component information

ChemComp-TTP:
THYMIDINE-5'-TRIPHOSPHATE

-
Macromolecule #8: ZINC ION

MacromoleculeName: ZINC ION / type: ligand / ID: 8 / Number of copies: 4 / Formula: ZN
Molecular weightTheoretical: 65.409 Da

-
Experimental details

-
Structure determination

Methodcryo EM
Processingsingle particle reconstruction
Aggregation stateparticle

-
Sample preparation

BufferpH: 7.9
Details: 20 mM HEPES-KOH pH 7.9, 400 mM potassium acetate, 5 mM magnesium acetate, 0.1 mM dTTP
GridModel: Quantifoil R1.2/1.3 / Material: COPPER / Mesh: 300 / Pretreatment - Type: GLOW DISCHARGE / Pretreatment - Time: 60 sec.
VitrificationCryogen name: ETHANE / Chamber humidity: 100 % / Chamber temperature: 285 K / Instrument: FEI VITROBOT MARK IV
DetailsA260 = 17

-
Electron microscopy

MicroscopeFEI TITAN KRIOS
Specialist opticsEnergy filter - Name: GIF Bioquantum / Energy filter - Slit width: 20 eV
Image recordingFilm or detector model: GATAN K3 BIOQUANTUM (6k x 4k) / Number grids imaged: 1 / Number real images: 10627 / Average exposure time: 1.02 sec. / Average electron dose: 59.6 e/Å2
Electron beamAcceleration voltage: 300 kV / Electron source: FIELD EMISSION GUN
Electron opticsC2 aperture diameter: 50.0 µm / Illumination mode: FLOOD BEAM / Imaging mode: BRIGHT FIELD / Cs: 2.7 mm / Nominal defocus max: 3.0 µm / Nominal defocus min: 1.5 µm / Nominal magnification: 130000
Sample stageSpecimen holder model: FEI TITAN KRIOS AUTOGRID HOLDER / Cooling holder cryogen: NITROGEN
Experimental equipment
Model: Titan Krios / Image courtesy: FEI Company

+
Image processing

Particle selectionNumber selected: 323700
CTF correctionSoftware - Name: CTFFIND (ver. 4.1) / Type: PHASE FLIPPING AND AMPLITUDE CORRECTION
Startup modelType of model: INSILICO MODEL
Final reconstructionNumber classes used: 1 / Applied symmetry - Point group: C1 (asymmetric) / Resolution.type: BY AUTHOR / Resolution: 3.2 Å / Resolution method: FSC 0.143 CUT-OFF / Software - Name: RELION (ver. 5.0) / Number images used: 30612
Initial angle assignmentType: MAXIMUM LIKELIHOOD
Final angle assignmentType: MAXIMUM LIKELIHOOD / Software - Name: RELION (ver. 5.0)
FSC plot (resolution estimation)

-
Atomic model buiding 1

RefinementProtocol: AB INITIO MODEL
Output model

PDB-9dou:
Taeniopygia guttata R2 retrotransposon (R2Tg) initiating target-primed reverse transcription

+
About Yorodumi

-
News

-
Feb 9, 2022. New format data for meta-information of EMDB entries

New format data for meta-information of EMDB entries

  • Version 3 of the EMDB header file is now the official format.
  • The previous official version 1.9 will be removed from the archive.

Related info.:EMDB header

External links:wwPDB to switch to version 3 of the EMDB data model

-
Aug 12, 2020. Covid-19 info

Covid-19 info

URL: https://pdbj.org/emnavi/covid19.php

New page: Covid-19 featured information page in EM Navigator.

Related info.:Covid-19 info / Mar 5, 2020. Novel coronavirus structure data

+
Mar 5, 2020. Novel coronavirus structure data

Novel coronavirus structure data

Related info.:Yorodumi Speices / Aug 12, 2020. Covid-19 info

External links:COVID-19 featured content - PDBj / Molecule of the Month (242)：Coronavirus Proteases

+
Jan 31, 2019. EMDB accession codes are about to change! (news from PDBe EMDB page)

EMDB accession codes are about to change! (news from PDBe EMDB page)

  • The allocation of 4 digits for EMDB accession codes will soon come to an end. Whilst these codes will remain in use, new EMDB accession codes will include an additional digit and will expand incrementally as the available range of codes is exhausted. The current 4-digit format prefixed with “EMD-” (i.e. EMD-XXXX) will advance to a 5-digit format (i.e. EMD-XXXXX), and so on. It is currently estimated that the 4-digit codes will be depleted around Spring 2019, at which point the 5-digit format will come into force.
  • The EM Navigator/Yorodumi systems omit the EMD- prefix.

Related info.:Q: What is EMD? / ID/Accession-code notation in Yorodumi/EM Navigator

External links:EMDB Accession Codes are Changing Soon! / Contact to PDBj

+
Jul 12, 2017. Major update of PDB

Major update of PDB

  • wwPDB released updated PDB data conforming to the new PDBx/mmCIF dictionary.
  • This is a major update changing the version number from 4 to 5, and with Remediation, in which all the entries are updated.
  • In this update, many items about electron microscopy experimental information are reorganized (e.g. em_software).
  • Now, EM Navigator and Yorodumi are based on the updated data.

External links:wwPDB Remediation / Enriched Model Files Conforming to OneDep Data Standards Now Available in the PDB FTP Archive

-
Yorodumi

Thousand views of thousand structures

  • Yorodumi is a browser for structure data from EMDB, PDB, SASBDB, etc.
  • This page is also the successor to EM Navigator detail page, and also detail information page/front-end page for Omokage search.
  • The word "yorodu" (or yorozu) is an old Japanese word meaning "ten thousand". "mi" (miru) is to see.

Related info.:EMDB / PDB / SASBDB / Comparison of 3 databanks / Yorodumi Search / Aug 31, 2016. New EM Navigator & Yorodumi / Yorodumi Papers / Jmol/JSmol / Function and homology information / Changes in new EM Navigator and Yorodumi

Read more