登録情報 | データベース: EMDB / ID: EMD-43107 |
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タイトル | Structure of human Slo1 and human LRRC26 in EDTA - LRRD masked |
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マップデータ | Unsharpened map |
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試料 | - 複合体: Hetero-octameric (4:4) complex of human Slo1 and human LRRC26
- タンパク質・ペプチド: Calcium-activated potassium channel subunit alpha-1
- タンパク質・ペプチド: Leucine-rich repeat-containing protein 26
- リガンド: POTASSIUM ION
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キーワード | Slo1 / BK / maxiK / potassium channel / voltage sensor / VSD / resting state / LRRC26 / Gamma1 / TRANSPORT PROTEIN |
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機能・相同性 | 機能・相同性情報
positive regulation of voltage-gated potassium channel activity / Acetylcholine inhibits contraction of outer hair cells / micturition / Ca2+ activated K+ channels / response to carbon monoxide / potassium channel activator activity / large conductance calcium-activated potassium channel activity / calcium-activated potassium channel activity / negative regulation of cell volume / smooth muscle contraction involved in micturition ...positive regulation of voltage-gated potassium channel activity / Acetylcholine inhibits contraction of outer hair cells / micturition / Ca2+ activated K+ channels / response to carbon monoxide / potassium channel activator activity / large conductance calcium-activated potassium channel activity / calcium-activated potassium channel activity / negative regulation of cell volume / smooth muscle contraction involved in micturition / intracellular potassium ion homeostasis / Sensory processing of sound by inner hair cells of the cochlea / response to osmotic stress / cGMP effects / voltage-gated potassium channel activity / potassium channel regulator activity / voltage-gated potassium channel complex / potassium ion transmembrane transport / regulation of membrane potential / potassium ion transport / caveola / response to calcium ion / vasodilation / actin binding / transmembrane transporter binding / postsynaptic membrane / cytoskeleton / response to hypoxia / positive regulation of apoptotic process / apical plasma membrane / extracellular exosome / metal ion binding / identical protein binding / membrane / plasma membrane / cytoplasm類似検索 - 分子機能 : / Ca2+-activated K+ channel Slowpoke, TrkA_C like domain / Calcium-activated potassium channel BK, alpha subunit / : / Calcium-activated BK potassium channel alpha subunit / Calcium-activated potassium channel slowpoke-like RCK domain / Regulator of K+ conductance, N-terminal / RCK N-terminal domain profile. / Leucine rich repeat / Leucine-rich repeat, typical subtype ...: / Ca2+-activated K+ channel Slowpoke, TrkA_C like domain / Calcium-activated potassium channel BK, alpha subunit / : / Calcium-activated BK potassium channel alpha subunit / Calcium-activated potassium channel slowpoke-like RCK domain / Regulator of K+ conductance, N-terminal / RCK N-terminal domain profile. / Leucine rich repeat / Leucine-rich repeat, typical subtype / Leucine-rich repeats, typical (most populated) subfamily / Leucine-rich repeat / Leucine-rich repeat domain superfamily / Ion transport domain / Ion transport protein / NAD(P)-binding domain superfamily類似検索 - ドメイン・相同性 Calcium-activated potassium channel subunit alpha-1 / Leucine-rich repeat-containing protein 26類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) |
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手法 | 単粒子再構成法 / クライオ電子顕微鏡法 / 解像度: 2.82 Å |
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データ登録者 | Pal K / Kallure GS / Chowdhury S |
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資金援助 | 米国, 1件 Organization | Grant number | 国 |
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National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | 1R01GM145719 | 米国 |
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引用 | ジャーナル: To Be Published タイトル: Structure of human Slo1 and human LRRC26 in EDTA - LRRD masked 著者: Pal K / Kallure GS / Chowdhury S |
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履歴 | 登録 | 2023年12月11日 | - |
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ヘッダ(付随情報) 公開 | 2024年12月25日 | - |
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マップ公開 | 2024年12月25日 | - |
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更新 | 2025年5月14日 | - |
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現状 | 2025年5月14日 | 処理サイト: RCSB / 状態: 公開 |
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