登録情報 | データベース: EMDB / ID: EMD-42356 |
---|
タイトル | Cryo-EM map of transglutaminase 2 bound to calcium |
---|
マップデータ | |
---|
試料 | - 複合体: Transglutaminase 2 bound to calcium
- タンパク質・ペプチド: Protein-glutamine gamma-glutamyltransferase 2
|
---|
キーワード | GDP / Complex / Signaling / G-protein / Cancer / cryo-EM / TRANSFERASE |
---|
機能・相同性 | 機能・相同性情報
histone serotonyltransferase activity / histone dopaminyltransferase activity / peptide noradrenalinyltransferase activity / peptide histaminyltransferase activity / cellular response to serotonin / regulation of apoptotic cell clearance / protein deamination / protein-glutamine glutaminase activity / protein-glutamine glutaminase / protein-glutamine gamma-glutamyltransferase ...histone serotonyltransferase activity / histone dopaminyltransferase activity / peptide noradrenalinyltransferase activity / peptide histaminyltransferase activity / cellular response to serotonin / regulation of apoptotic cell clearance / protein deamination / protein-glutamine glutaminase activity / protein-glutamine glutaminase / protein-glutamine gamma-glutamyltransferase / positive regulation of mitochondrial calcium ion concentration / salivary gland cavitation / protein-glutamine gamma-glutamyltransferase activity / negative regulation of endoplasmic reticulum calcium ion concentration / dopamine secretion / peptide cross-linking / branching involved in salivary gland morphogenesis / cellular response to dopamine / positive regulation of small GTPase mediated signal transduction / 加水分解酵素; プロテアーゼ; ペプチド結合加水分解酵素 / apoptotic cell clearance / cellular response to cocaine / positive regulation of neurogenesis / positive regulation of sprouting angiogenesis / positive regulation of cell adhesion / 転移酵素; アシル基を移すもの; アミノアシル基以外のアシル基を移すもの / extracellular matrix / positive regulation of GTPase activity / bone development / protein homooligomerization / nucleosome / peptidase activity / phospholipase C-activating G protein-coupled receptor signaling pathway / gene expression / collagen-containing extracellular matrix / regulation of apoptotic process / positive regulation of apoptotic process / focal adhesion / calcium ion binding / chromatin / GTP binding / perinuclear region of cytoplasm / endoplasmic reticulum / mitochondrion / proteolysis / extracellular exosome / nucleus / plasma membrane / cytosol類似検索 - 分子機能 : / Transglutaminase, N-terminal / Transglutaminase, C-terminal / Transglutaminase, active site / Protein-glutamine gamma-glutamyltransferase, animal / Transglutaminase, C-terminal domain superfamily / Transglutaminase family / Transglutaminase family, C-terminal ig like domain / Transglutaminases active site. / Transglutaminase-like superfamily ...: / Transglutaminase, N-terminal / Transglutaminase, C-terminal / Transglutaminase, active site / Protein-glutamine gamma-glutamyltransferase, animal / Transglutaminase, C-terminal domain superfamily / Transglutaminase family / Transglutaminase family, C-terminal ig like domain / Transglutaminases active site. / Transglutaminase-like superfamily / Transglutaminase/protease-like homologues / Transglutaminase-like / Transglutaminase-like superfamily / Papain-like cysteine peptidase superfamily / Immunoglobulin E-set / Immunoglobulin-like fold類似検索 - ドメイン・相同性 Protein-glutamine gamma-glutamyltransferase 2類似検索 - 構成要素 |
---|
生物種 | Homo sapiens (ヒト) |
---|
手法 | 単粒子再構成法 / クライオ電子顕微鏡法 / 解像度: 3.44 Å |
---|
データ登録者 | Aplin C / Cerione RA |
---|
資金援助 | 米国, 1件 Organization | Grant number | 国 |
---|
National Institutes of Health/National Cancer Institute (NIH/NCI) | R01CA201402-09 | 米国 |
|
---|
引用 | ジャーナル: To Be Published タイトル: Conformational activation and inhibition of transglutaminase 2 determined by static and time resolved small-angle X-ray scattering and cryoelectron microscopy 著者: Aplin C / Zielinski KA / Pabit S / Ogunribido D / Katt WP / Pollack L / Cerione RA / Milano SK |
---|
履歴 | 登録 | 2023年10月16日 | - |
---|
ヘッダ(付随情報) 公開 | 2024年7月31日 | - |
---|
マップ公開 | 2024年7月31日 | - |
---|
更新 | 2024年7月31日 | - |
---|
現状 | 2024年7月31日 | 処理サイト: RCSB / 状態: 公開 |
---|
|
---|