登録情報 | データベース: EMDB / ID: EMD-36898 |
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タイトル | The cryo-EM map of TIC-TIEA complex |
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マップデータ | Cryo-EM structure of TIEA-TIC |
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試料 | - 複合体: The cryo-EM map of TIC-TIEA complex
- タンパク質・ペプチド: DNA-directed RNA polymerase subunit beta
- タンパク質・ペプチド: DNA-directed RNA polymerase subunit beta'
- タンパク質・ペプチド: DNA-directed RNA polymerase subunit omega
- タンパク質・ペプチド: RNA polymerase sigma factor RpoD
- タンパク質・ペプチド: DNA-directed RNA polymerase subunit alpha
- タンパク質・ペプチド: 15 kDa RNA polymerase-binding protein
- DNA: DNA (61-MER)
- DNA: DNA (63-MER)
- RNA: RNA (5'-R(*AP*GP*GP*UP*A)-3')
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キーワード | bacteriophage T4 / RNA polymerase / transcription / inhibitor / elongation accelerator / complex / TRANSCRIPTION/DNA/RNA / TRANSCRIPTION-DNA-RNA complex |
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機能・相同性 | 機能・相同性情報
sigma factor antagonist complex / RNA polymerase complex / submerged biofilm formation / cellular response to cell envelope stress / regulation of DNA-templated transcription initiation / sigma factor activity / bacterial-type flagellum assembly / bacterial-type RNA polymerase core enzyme binding / cytosolic DNA-directed RNA polymerase complex / bacterial-type flagellum-dependent cell motility ...sigma factor antagonist complex / RNA polymerase complex / submerged biofilm formation / cellular response to cell envelope stress / regulation of DNA-templated transcription initiation / sigma factor activity / bacterial-type flagellum assembly / bacterial-type RNA polymerase core enzyme binding / cytosolic DNA-directed RNA polymerase complex / bacterial-type flagellum-dependent cell motility / nitrate assimilation / transcription elongation factor complex / regulation of DNA-templated transcription elongation / transcription antitermination / DNA-templated transcription initiation / cell motility / ribonucleoside binding / : / : / : / : / : / : / DNA-directed RNA polymerase / response to heat / protein-containing complex assembly / intracellular iron ion homeostasis / DNA replication / protein dimerization activity / response to antibiotic / negative regulation of DNA-templated transcription / magnesium ion binding / DNA binding / zinc ion binding / membrane / cytosol / cytoplasm類似検索 - 分子機能 Bacteriophage T4, P15K, RNA polymerase binding / Phage RNA polymerase binding, RpbA / RNA polymerase sigma factor 70, non-essential domain / Sigma-70, non-essential region / RNA polymerase sigma factor 70, region 1.1 / Sigma-70 factor, region 1.1 superfamily / Sigma-70 factor, region 1.1 / Sigma-70 factors family signature 1. / RNA polymerase sigma factor RpoD, C-terminal / RNA polymerase sigma factor RpoD ...Bacteriophage T4, P15K, RNA polymerase binding / Phage RNA polymerase binding, RpbA / RNA polymerase sigma factor 70, non-essential domain / Sigma-70, non-essential region / RNA polymerase sigma factor 70, region 1.1 / Sigma-70 factor, region 1.1 superfamily / Sigma-70 factor, region 1.1 / Sigma-70 factors family signature 1. / RNA polymerase sigma factor RpoD, C-terminal / RNA polymerase sigma factor RpoD / : / RNA polymerase sigma-70 region 1.2 / Sigma-70 factor, region 1.2 / RNA polymerase sigma-70 region 3 / Sigma-70 region 3 / Sigma-70 factors family signature 2. / RNA polymerase sigma-70 / RNA polymerase sigma-70 region 4 / Sigma-70, region 4 / RNA polymerase sigma-70 region 2 / RNA polymerase sigma-70 like domain / Sigma-70 region 2 / RNA polymerase sigma factor, region 2 / RNA polymerase sigma factor, region 3/4-like / DNA-directed RNA polymerase, omega subunit / DNA-directed RNA polymerase, subunit beta-prime, bacterial type / DNA-directed RNA polymerase, beta subunit, external 1 domain superfamily / DNA-directed RNA polymerase, beta subunit, external 1 domain / RNA polymerase beta subunit external 1 domain / RNA polymerase, alpha subunit, C-terminal / Bacterial RNA polymerase, alpha chain C terminal domain / DNA-directed RNA polymerase, alpha subunit / DNA-directed RNA polymerase beta subunit, bacterial-type / DNA-directed RNA polymerase, subunit beta-prime / RNA polymerase Rpb6 / RNA polymerase, subunit omega/Rpo6/RPB6 / RNA polymerase Rpb6 / RNA polymerase Rpb2, domain 2 superfamily / RNA polymerase Rpb1, domain 3 superfamily / RPB6/omega subunit-like superfamily / DNA-directed RNA polymerase, insert domain / DNA-directed RNA polymerase, RpoA/D/Rpb3-type / RNA polymerase Rpb3/RpoA insert domain / RNA polymerase Rpb3/Rpb11 dimerisation domain / RNA polymerases D / RNA polymerase Rpb1, clamp domain superfamily / RNA polymerase Rpb1, domain 3 / RNA polymerase Rpb1, domain 3 / RNA polymerase Rpb1, domain 1 / RNA polymerase Rpb1, domain 1 / RNA polymerase, beta subunit, protrusion / RNA polymerase beta subunit / RNA polymerase, alpha subunit / RNA polymerase Rpb1, domain 5 / RNA polymerase Rpb1, domain 4 / RNA polymerase Rpb1, domain 2 / RNA polymerase Rpb1, domain 5 / RNA polymerase Rpb1, domain 4 / DNA-directed RNA polymerase, insert domain superfamily / RNA polymerase, N-terminal / RNA polymerase Rpb1, funnel domain superfamily / RNA polymerase I subunit A N-terminus / RNA polymerase Rpb2, domain 2 / RNA polymerase Rpb2, domain 2 / RNA polymerase, RBP11-like subunit / RNA polymerase, beta subunit, conserved site / RNA polymerase Rpb2, domain 7 / RNA polymerase Rpb2, domain 3 / RNA polymerase Rpb2, OB-fold / RNA polymerase Rpb2, domain 7 / RNA polymerase Rpb2, domain 3 / RNA polymerases beta chain signature. / DNA-directed RNA polymerase, subunit 2, hybrid-binding domain / DNA-directed RNA polymerase, subunit 2 / DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily / RNA polymerase Rpb2, domain 6 / Winged helix-like DNA-binding domain superfamily類似検索 - ドメイン・相同性 RNA polymerase sigma factor RpoD / 15 kDa RNA polymerase-binding protein / DNA-directed RNA polymerase subunit alpha / DNA-directed RNA polymerase subunit omega / DNA-directed RNA polymerase subunit beta' / DNA-directed RNA polymerase subunit beta類似検索 - 構成要素 |
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生物種 |  Escherichia coli K-12 (大腸菌) / Escherichia phage T4 (ファージ) |
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手法 | 単粒子再構成法 / クライオ電子顕微鏡法 / 解像度: 3.5 Å |
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データ登録者 | Zhang KN / Liu Y / Chen M / Wang Y / Lin W / Li M / Zhang X / Gao Y / Gong Q / Chen H ...Zhang KN / Liu Y / Chen M / Wang Y / Lin W / Li M / Zhang X / Gao Y / Gong Q / Chen H / Steve M / Li S / Zhang K / Liu B |
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資金援助 | 中国, 1件 Organization | Grant number | 国 |
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Other government | | 中国 |
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引用 | ジャーナル: To Be Published タイトル: TIEA inhibits sigma70-dependent transcriptions, accelerates elongation speed and elevates transcription error 著者: Zhang KN / Liu Y / Chen M / Wang Y / Lin W / Li M / Zhang X / Gao Y / Gong Q / Chen H / Steve M / Li S / Zhang K / Liu B |
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履歴 | 登録 | 2023年7月21日 | - |
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ヘッダ(付随情報) 公開 | 2024年11月13日 | - |
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マップ公開 | 2024年11月13日 | - |
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更新 | 2024年11月13日 | - |
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現状 | 2024年11月13日 | 処理サイト: PDBc / 状態: 公開 |
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