登録情報 | データベース: EMDB / ID: EMD-15123 |
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タイトル | S. cerevisiae APC/C-Cdh1 complex |
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マップデータ | whole map |
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試料 | - 複合体: Anaphase promoting complex/cyclosome (APC/C) in complex with Cdh1 and Hsl1
- リガンド: x 1種
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キーワード | APC/C / ubiqutiniation / D-box / Cdh1 / CELL CYCLE |
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機能・相同性 | 機能・相同性情報
anaphase-promoting complex assembly / negative regulation of anaphase-promoting complex-dependent catabolic process / positive regulation of mitotic actomyosin contractile ring contraction / deactivation of mitotic spindle assembly checkpoint / ascospore wall assembly / 合成酵素; C-N結合を形成; 酸-D-アミノ酸リガーゼ(ペプチド合成) / ubiquitin-protein transferase activator activity / anaphase-promoting complex / metaphase/anaphase transition of mitotic cell cycle / regulation of meiotic cell cycle ...anaphase-promoting complex assembly / negative regulation of anaphase-promoting complex-dependent catabolic process / positive regulation of mitotic actomyosin contractile ring contraction / deactivation of mitotic spindle assembly checkpoint / ascospore wall assembly / 合成酵素; C-N結合を形成; 酸-D-アミノ酸リガーゼ(ペプチド合成) / ubiquitin-protein transferase activator activity / anaphase-promoting complex / metaphase/anaphase transition of mitotic cell cycle / regulation of meiotic cell cycle / anaphase-promoting complex-dependent catabolic process / anaphase-promoting complex binding / positive regulation of mitotic metaphase/anaphase transition / positive regulation of ubiquitin protein ligase activity / positive regulation of protein autoubiquitination / protein K11-linked ubiquitination / reciprocal meiotic recombination / regulation of mitotic metaphase/anaphase transition / exit from mitosis / ligase activity / cullin family protein binding / mitotic sister chromatid segregation / Antigen processing: Ubiquitination & Proteasome degradation / ubiquitin ligase inhibitor activity / enzyme regulator activity / negative regulation of DNA-templated DNA replication initiation / nuclear periphery / cyclin binding / regulation of mitotic cell cycle / kinetochore / spindle pole / ubiquitin protein ligase activity / chromatin organization / ubiquitin-dependent protein catabolic process / molecular adaptor activity / protein kinase activity / protein ubiquitination / protein phosphorylation / cell division / ubiquitin protein ligase binding / mitochondrion / zinc ion binding / ATP binding / identical protein binding / nucleus / cytosol / cytoplasm類似検索 - 分子機能 Anaphase-promoting complex subunit 15/mnd2 / Anaphase-promoting complex subunit Mnd2 / Anaphase-promoting complex, subunit 9 / Apc15p protein / Anaphase-promoting complex subunit 9 / The WD repeat Cdc20/Fizzy family / Cdc23 / Apc13 / Tetratricopeptide repeat 2 / Anaphase promoting complex subunit 8 / Cdc23 ...Anaphase-promoting complex subunit 15/mnd2 / Anaphase-promoting complex subunit Mnd2 / Anaphase-promoting complex, subunit 9 / Apc15p protein / Anaphase-promoting complex subunit 9 / The WD repeat Cdc20/Fizzy family / Cdc23 / Apc13 / Tetratricopeptide repeat 2 / Anaphase promoting complex subunit 8 / Cdc23 / Apc13p protein / Tetratricopeptide repeat / Anaphase-promoting complex subunit 4 / Anaphase-promoting complex subunit 4 long domain / Anaphase-promoting complex subunit 1 / Anaphase-promoting complex subunit 5 domain / Anaphase-promoting complex subunit 5 / Anaphase-promoting complex subunit 5 / Anaphase-promoting complex, cyclosome, subunit 4 / Anaphase-promoting complex subunit APC10/Doc1 / Anaphase-promoting complex, subunit CDC26 / Anaphase-promoting complex APC subunit CDC26 / Anaphase-promoting complex subunit 11, RING-H2 finger / Anaphase-promoting complex subunit 11 RING-H2 finger / Anaphase-promoting complex subunit 2, C-terminal / Anaphase-promoting complex subunit 2 / Anaphase promoting complex (APC) subunit 2 / Anaphase promoting complex (APC) subunit 2 / APC10/DOC domain / Anaphase-promoting complex, subunit 10 (APC10) / DOC domain profile. / Anaphase-promoting complex, subunit 10 (APC10) / Anaphase-promoting complex, cyclosome, subunit 3 / TPR repeat / Anaphase-promoting complex subunit 4, WD40 domain / Anaphase-promoting complex subunit 4 WD40 domain / Tetratricopeptide repeat / : / Cullin, N-terminal / Cullin homology domain / Cullin homology domain superfamily / Cullin family / Cullin family profile. / Tetratricopeptide repeat / Tetratricopeptide repeat / Tetratricopeptide repeat / TPR repeat region circular profile. / TPR repeat profile. / Tetratricopeptide repeats / Tetratricopeptide repeat / Galactose-binding-like domain superfamily / Zinc finger RING-type profile. / Zinc finger, RING-type / Armadillo-like helical / Tetratricopeptide-like helical domain superfamily / Zinc finger, RING/FYVE/PHD-type / Winged helix DNA-binding domain superfamily / WD40 repeat, conserved site / Trp-Asp (WD) repeats signature. / WD domain, G-beta repeat / Trp-Asp (WD) repeats profile. / WD40 repeats / Serine/threonine-protein kinase, active site / Serine/Threonine protein kinases active-site signature. / WD40 repeat / WD40-repeat-containing domain superfamily / Winged helix-like DNA-binding domain superfamily / Protein kinase domain / Serine/Threonine protein kinases, catalytic domain / WD40/YVTN repeat-like-containing domain superfamily / Protein kinase, ATP binding site / Protein kinases ATP-binding region signature. / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily類似検索 - ドメイン・相同性 CDH1 isoform 1 / HSL1 isoform 1 / Anaphase-promoting complex subunit CDC16 / Anaphase-promoting complex subunit CDC26 / Anaphase-promoting complex subunit CDC23 / Anaphase-promoting complex subunit CDC27 / Anaphase-promoting complex subunit MND2 / Anaphase-promoting complex subunit DOC1 / Anaphase-promoting complex subunit 1 / Anaphase-promoting complex subunit 4 ...CDH1 isoform 1 / HSL1 isoform 1 / Anaphase-promoting complex subunit CDC16 / Anaphase-promoting complex subunit CDC26 / Anaphase-promoting complex subunit CDC23 / Anaphase-promoting complex subunit CDC27 / Anaphase-promoting complex subunit MND2 / Anaphase-promoting complex subunit DOC1 / Anaphase-promoting complex subunit 1 / Anaphase-promoting complex subunit 4 / Anaphase-promoting complex subunit 5 / Anaphase-promoting complex subunit 9 / Anaphase-promoting complex subunit 11 / Anaphase-promoting complex subunit SWM1 / Anaphase-promoting complex subunit 2類似検索 - 構成要素 |
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生物種 |  Saccharomyces cerevisiae (パン酵母) |
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手法 | 単粒子再構成法 / クライオ電子顕微鏡法 / 解像度: 3.5 Å |
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データ登録者 | Barford D / Vazquez-Fernandez E / Zhang Z / Yang J |
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資金援助 | 英国, 2件 Organization | Grant number | 国 |
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Medical Research Council (MRC, United Kingdom) | MC_UP_1201/6 | 英国 | Cancer Research UK | C576/A14109 | 英国 |
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引用 | ジャーナル: To Be Published タイトル: Cryo-EM structure of the S. cerevisiae APC/C-Cdh1 complex 著者: Barford D / Vazquez-Fernandez E / Zhang Z / Yang J |
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履歴 | 登録 | 2022年6月9日 | - |
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ヘッダ(付随情報) 公開 | 2022年8月31日 | - |
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マップ公開 | 2022年8月31日 | - |
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更新 | 2024年11月6日 | - |
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現状 | 2024年11月6日 | 処理サイト: PDBe / 状態: 公開 |
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