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- SASDH42: Bovine Pancreatic Trypsin Inhibitor (BPTI) in solution environmen... -
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Open data
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Basic information
Entry | Database: SASBDB / ID: SASDH42 |
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![]() | Bovine Pancreatic Trypsin Inhibitor (BPTI) in solution environment at pH 7.5
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Function / homology | ![]() trypsinogen activation / negative regulation of serine-type endopeptidase activity / sulfate binding / negative regulation of platelet aggregation / potassium channel inhibitor activity / zymogen binding / molecular function inhibitor activity / negative regulation of thrombin-activated receptor signaling pathway / serine protease inhibitor complex / serine-type endopeptidase inhibitor activity ...trypsinogen activation / negative regulation of serine-type endopeptidase activity / sulfate binding / negative regulation of platelet aggregation / potassium channel inhibitor activity / zymogen binding / molecular function inhibitor activity / negative regulation of thrombin-activated receptor signaling pathway / serine protease inhibitor complex / serine-type endopeptidase inhibitor activity / protease binding / calcium ion binding / extracellular space Similarity search - Function |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
-Data source
SASBDB page | ![]() |
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-Related structure data
Similar structure data | Similarity search - Function & homology ![]() |
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External links
Related items in Molecule of the Month |
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-Models
Model #3893 | ![]() Type: dummy / Software: (dammif (r9988)) / Radius of dummy atoms: 1.00 A / Symmetry: P1 / Chi-square value: 1.318 / P-value: 0.000004 |
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Model #3894 | ![]() Type: dummy / Radius of dummy atoms: 1.00 A / Symmetry: P1 / Chi-square value: 1.318 / P-value: 0.000004 |
Model #3895 | ![]() Type: dummy / Software: (dammif (r9988)) / Radius of dummy atoms: 1.00 A / Symmetry: P1 / Chi-square value: 1.320 / P-value: 0.000004 |
Model #3896 | ![]() Type: dummy / Radius of dummy atoms: 0.97 A / Symmetry: P1 / Chi-square value: 1.320 / P-value: 0.000004 |
Model #3897 | ![]() Type: dummy / Software: (DAMFILT 5.0 (r9988)) / Radius of dummy atoms: 1.25 A / Symmetry: P1 / Chi-square value: 1.318 / P-value: 0.000004 |
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Sample
![]() | Name: Bovine Pancreatic Trypsin Inhibitor (BPTI) in solution environment at pH 7.5 Specimen concentration: 2.50-10.00 |
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Buffer | Name: 50 mM Tris-HCL, 150 mM NaCl / pH: 7.5 Comment: PDI was incubated with 0.5mM TCEP to reduce the Active sites one hour before SAXS data collection |
Entity #1949 | Name: BPTI / Type: protein / Description: Pancreatic trypsin inhibitor / Formula weight: 6.517 / Num. of mol.: 2 / Source: Bos taurus / References: UniProt: P00974 Sequence: RPDFCLEPPY TGPCKARIIR YFYNAKAGLC QTFVYGGCRA KRNNFKSAED CMRTCGGA |
-Experimental information
Beam | Instrument name: Advanced Photon Source (APS), Argonne National Laboratory BioCAT 18ID City: Lemont, IL / 国: USA ![]() | |||||||||||||||||||||||||||||||||
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Detector | Name: Pilatus3 X 1M / Pixsize x: 0.172 mm | |||||||||||||||||||||||||||||||||
Scan | Measurement date: Nov 4, 2015 / Storage temperature: 10 °C / Cell temperature: 10 °C / Exposure time: 1 sec. / Number of frames: 8 / Unit: 1/A /
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Distance distribution function P(R) |
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Result | Comments: Bovine Pancreatic Trypsin Inhibitor (BPTI) was purchased from SIGMA-ALDRICH in the form of lyophilized powder, dissolved with suspension medium and used directly without any further ...Comments: Bovine Pancreatic Trypsin Inhibitor (BPTI) was purchased from SIGMA-ALDRICH in the form of lyophilized powder, dissolved with suspension medium and used directly without any further purification. CAUTION! Sample likely aggregated.
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