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- SASDGW5: Suppressor of Fused from Drosophila (Suppressor of fused homolog,... -
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Open data
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Basic information
Entry | Database: SASBDB / ID: SASDGW5 |
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![]() | Suppressor of Fused from Drosophila
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Function / homology | ![]() cytoplasmic sequestering of transcription factor / negative regulation of nucleocytoplasmic transport / Hedgehog 'off' state / Degradation of GLI1 by the proteasome / GLI3 is processed to GLI3R by the proteasome / Hedgehog 'on' state / nuclear localization sequence binding / transcription factor binding / negative regulation of smoothened signaling pathway / protein sequestering activity ...cytoplasmic sequestering of transcription factor / negative regulation of nucleocytoplasmic transport / Hedgehog 'off' state / Degradation of GLI1 by the proteasome / GLI3 is processed to GLI3R by the proteasome / Hedgehog 'on' state / nuclear localization sequence binding / transcription factor binding / negative regulation of smoothened signaling pathway / protein sequestering activity / negative regulation of DNA-binding transcription factor activity / protein-containing complex / nucleus / cytoplasm / cytosol Similarity search - Function |
Biological species | ![]() ![]() |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
-Data source
SASBDB page | ![]() |
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-Related structure data
Similar structure data | Similarity search - Function & homology ![]() |
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-Models
Model #3798 | ![]() Type: atomic / Symmetry: P1 Comment: Model built with Dadimodo using 2 domains as rigid bodies and a 5-residue flexible linker. Chi-square value: 3.415104 |
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Model #3799 | ![]() Type: atomic / Symmetry: P1 Comment: Model built with Dadimodo using 2 domains as rigid bodies and a 5-residue flexible linker. Chi-square value: 3.090564 |
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Sample
![]() | Name: Suppressor of Fused from Drosophila / Specimen concentration: 10 mg/ml |
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Buffer | Name: 50 mM bis-TRIS pH 5.5, 200 mM NaCl, 10% glycerol / pH: 5.5 |
Entity #1903 | Name: dSuFu / Type: protein / Description: Suppressor of fused homolog / Formula weight: 52.787 / Num. of mol.: 1 / Source: Drosophila melanogaster / References: UniProt: q9vg38 Sequence: MAEANLDKKP EVKPPPGLKA IIDHLGQVYP NQPNPLQVTT LLKYWLGGQD PLDYISMYNY PGDVDRNVPP HWHYISFGLS DLHGDERVHL REEGVTRSGM GFELTFRLAK TEIELKQQIE NPEKPQRPPT WPANLLQAIG RYCFQTGNGL CFGDNIPWRK SLDGSTTSKL ...Sequence: MAEANLDKKP EVKPPPGLKA IIDHLGQVYP NQPNPLQVTT LLKYWLGGQD PLDYISMYNY PGDVDRNVPP HWHYISFGLS DLHGDERVHL REEGVTRSGM GFELTFRLAK TEIELKQQIE NPEKPQRPPT WPANLLQAIG RYCFQTGNGL CFGDNIPWRK SLDGSTTSKL QNLLVAQDPQ LGCIDTPTGT VDFCQIVGVF DDELEQASRW NGRGVLNFLR QDMQTGGDWL VTNMDRQMSV FELFPETLLN LQDDLEKQGS DLAGVNADFT FRELKPTKEV KEEVDFQALS EKCANDENNR QLTDTQMKRE EPSFPQSMSM SSNSLHKSCP LDFQAQAPNC ISLDGIEITL APGVAKYLLL AIKDRIRHGR HFTFKAQHLA LTLVAESVTG SAVTVNEPYG VLGYWIQVLI PDELVPRLME DFRSAGLDEK CEPKERLELE WPDKNLKLII DQPEPVLPMS LDAAPLKM |
-Experimental information
Beam | Instrument name: SOLEIL SWING ![]() ![]() | ||||||||||||||||||||||||||||||||||||
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Detector | Name: AVIEX PCCD170170 / Type: CCD | ||||||||||||||||||||||||||||||||||||
Scan |
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Distance distribution function P(R) |
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Result |
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