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基本情報
登録情報 | ![]() |
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![]() | Wild-type full-length Liver Receptor Homolog-1/Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha peptide complex bound to the CYP7A1 promoter oligonucleotide duplex.
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機能・相同性 | ![]() primary ovarian follicle growth / positive regulation of glucocorticoid biosynthetic process / zygotic genome activation / positive regulation of tendon cell differentiation / morula formation / Regulation of gene expression in early pancreatic precursor cells / pancreas morphogenesis / inner cell mass cell differentiation / tissue development / acinar cell differentiation ...primary ovarian follicle growth / positive regulation of glucocorticoid biosynthetic process / zygotic genome activation / positive regulation of tendon cell differentiation / morula formation / Regulation of gene expression in early pancreatic precursor cells / pancreas morphogenesis / inner cell mass cell differentiation / tissue development / acinar cell differentiation / Sertoli cell development / positive regulation of T cell anergy / positive regulation of stem cell differentiation / embryonic cleavage / bile acid metabolic process / exocrine pancreas development / negative regulation of chondrocyte differentiation / embryo development ending in birth or egg hatching / cartilage development / homeostatic process / calcineurin-mediated signaling / somatic stem cell population maintenance / positive regulation of viral genome replication / positive regulation of T cell proliferation / neurogenesis / hormone-mediated signaling pathway / cellular response to leukemia inhibitory factor / cholesterol homeostasis / transcription coregulator binding / SUMOylation of intracellular receptors / phospholipid binding / Nuclear Receptor transcription pathway / positive regulation of T cell activation / negative regulation of inflammatory response / RNA polymerase II transcription regulator complex / nuclear receptor activity / sequence-specific double-stranded DNA binding / DNA-binding transcription activator activity, RNA polymerase II-specific / spermatogenesis / Estrogen-dependent gene expression / sequence-specific DNA binding / DNA-binding transcription factor activity, RNA polymerase II-specific / transcription cis-regulatory region binding / chromatin remodeling / RNA polymerase II cis-regulatory region sequence-specific DNA binding / DNA-binding transcription factor activity / chromatin binding / regulation of DNA-templated transcription / regulation of transcription by RNA polymerase II / chromatin / positive regulation of DNA-templated transcription / positive regulation of transcription by RNA polymerase II / DNA binding / zinc ion binding / nucleoplasm / nucleus / cytoplasm 類似検索 - 分子機能 |
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構造の表示
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-モデル
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試料
![]() | 名称: Wild-type full-length Liver Receptor Homolog-1/Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha peptide complex bound to the CYP7A1 promoter oligonucleotide duplex. 試料濃度: 7.5 mg/ml / Entity id: 1884 / 1885 / 1886 / 1887 |
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バッファ | 名称: 20 mM TRIS, 150 mM NaCl, 2% v/v glycerol, 0.5 mM CHAPS, 5 mM DTT pH: 7.5 |
要素 #1884 | 名称: LRH-1 / タイプ: protein / 記述: Liver Receptor Homolog-1 / 分子量: 64.144 / 分子数: 1 / 由来: Homo sapiens / 参照: UniProt: O00482 配列: MAHHHHHHVD DDDKMSENLY FQSMSSNSDT GDLQESLKHG LTPIGAGLPD RHGSPIPARG RLVMLPKVET EALGLARSHG EQGQMPENMQ VSQFKMVNYS YDEDLEELCP VCGDKVSGYH YGLLTCESCK GFFKRTVQNN KRYTCIENQN CQIDKTQRKR CPYCRFQKCL ...配列: MAHHHHHHVD DDDKMSENLY FQSMSSNSDT GDLQESLKHG LTPIGAGLPD RHGSPIPARG RLVMLPKVET EALGLARSHG EQGQMPENMQ VSQFKMVNYS YDEDLEELCP VCGDKVSGYH YGLLTCESCK GFFKRTVQNN KRYTCIENQN CQIDKTQRKR CPYCRFQKCL SVGMKLEAVR ADRMRGGRNK FGPMYKRDRA LKQQKKALIR ANGLKLEAMS QVIQAMPSDL TISSAIQNIH SASKGLPLNH AALPPTDYDR SPFVTSPISM TMPPHGSLQG YQTYGHFPSR AIKSEYPDPY TSSPESIMGY SYMDSYQTSS PASIPHLILE LLKCEPDEPQ VQAKIMAYLQ QEQANRSKHE KLSTFGLMCK MADQTLFSIV EWARSSIFFR ELKVDDQMKL LQNCWSELLI LDHIYRQVVH GKEGSIFLVT GQQVDYSIIA SQAGATLNNL MSHAQELVAK LRSLQFDQRE FVCLKFLVLF SLDVKNLENF QLVEGVQEQV NAALLDYTMC NYPQQTEKFG QLLLRLPEIR AISMQAEEYL YYKHLNGDVP YNNLLIEMLH AKRA |
要素 #1885 | 名称: PGC1 alpha / タイプ: protein 記述: Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha 分子量: 1.522 / 分子数: 1 / 由来: Homo sapiens 配列: EEPSLLKKLL LAPA |
要素 #1886 | タイプ: DNA / 記述: CYP7A1 Promoter Forward / 分子量: 3.75 / 分子数: 1 / 由来: Homo sapiens 配列: GTTCAAGGCC AG |
要素 #1887 | タイプ: DNA / 記述: CYP7A1 Promoter Reverse / 分子量: 3.701 / 分子数: 1 / 由来: Homo sapiens 配列: CTGGCCTTGA AC |
-実験情報
ビーム | 設備名称: Advanced Light Source (ALS) 12.3.1 (SIBYLS) / 地域: Berkeley, CA / 国: USA ![]() | |||||||||||||||||||||||||||||||||
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検出器 | 名称: Pilatus3 X 2M / Pixsize x: 172 mm | |||||||||||||||||||||||||||||||||
スキャン | 測定日: 2019年5月26日 / セル温度: 20 °C / 照射時間: 3 sec. / フレーム数: 500 / 単位: 1/A /
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距離分布関数 P(R) |
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