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- SASDG85: Wild-type full-length Liver Receptor Homolog-1/Peroxisome Prolife... -
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Open data
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Basic information
Entry | ![]() |
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![]() | Wild-type full-length Liver Receptor Homolog-1/Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha peptide complex bound to the CYP7A1 promoter oligonucleotide duplex.
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Function / homology | ![]() Regulation of gene expression in early pancreatic precursor cells / pancreas morphogenesis / calcineurin-mediated signaling / acinar cell differentiation / tissue development / bile acid metabolic process / embryo development ending in birth or egg hatching / homeostatic process / hormone-mediated signaling pathway / positive regulation of viral genome replication ...Regulation of gene expression in early pancreatic precursor cells / pancreas morphogenesis / calcineurin-mediated signaling / acinar cell differentiation / tissue development / bile acid metabolic process / embryo development ending in birth or egg hatching / homeostatic process / hormone-mediated signaling pathway / positive regulation of viral genome replication / transcription coregulator binding / SUMOylation of intracellular receptors / cellular response to leukemia inhibitory factor / cholesterol homeostasis / Nuclear Receptor transcription pathway / RNA polymerase II transcription regulator complex / phospholipid binding / nuclear receptor activity / sequence-specific double-stranded DNA binding / regulation of cell population proliferation / DNA-binding transcription activator activity, RNA polymerase II-specific / sequence-specific DNA binding / Estrogen-dependent gene expression / transcription cis-regulatory region binding / DNA-binding transcription factor activity, RNA polymerase II-specific / RNA polymerase II cis-regulatory region sequence-specific DNA binding / DNA-binding transcription factor activity / chromatin binding / regulation of transcription by RNA polymerase II / positive regulation of DNA-templated transcription / chromatin / regulation of DNA-templated transcription / positive regulation of transcription by RNA polymerase II / DNA binding / zinc ion binding / nucleoplasm / nucleus / cytoplasm Similarity search - Function |
Biological species | ![]() |
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Structure visualization
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Downloads & links
-Data source
SASBDB page | ![]() |
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-Related structure data
Similar structure data | Similarity search - Function & homology ![]() |
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-Models
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Sample
![]() | Name: Wild-type full-length Liver Receptor Homolog-1/Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha peptide complex bound to the CYP7A1 promoter oligonucleotide duplex. Specimen concentration: 7.5 mg/ml / Entity id: 1884 / 1885 / 1886 / 1887 |
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Buffer | Name: 20 mM TRIS, 150 mM NaCl, 2% v/v glycerol, 0.5 mM CHAPS, 5 mM DTT pH: 7.5 |
Entity #1884 | Name: LRH-1 / Type: protein / Description: Liver Receptor Homolog-1 / Formula weight: 64.144 / Num. of mol.: 1 / Source: Homo sapiens / References: UniProt: O00482 Sequence: MAHHHHHHVD DDDKMSENLY FQSMSSNSDT GDLQESLKHG LTPIGAGLPD RHGSPIPARG RLVMLPKVET EALGLARSHG EQGQMPENMQ VSQFKMVNYS YDEDLEELCP VCGDKVSGYH YGLLTCESCK GFFKRTVQNN KRYTCIENQN CQIDKTQRKR CPYCRFQKCL ...Sequence: MAHHHHHHVD DDDKMSENLY FQSMSSNSDT GDLQESLKHG LTPIGAGLPD RHGSPIPARG RLVMLPKVET EALGLARSHG EQGQMPENMQ VSQFKMVNYS YDEDLEELCP VCGDKVSGYH YGLLTCESCK GFFKRTVQNN KRYTCIENQN CQIDKTQRKR CPYCRFQKCL SVGMKLEAVR ADRMRGGRNK FGPMYKRDRA LKQQKKALIR ANGLKLEAMS QVIQAMPSDL TISSAIQNIH SASKGLPLNH AALPPTDYDR SPFVTSPISM TMPPHGSLQG YQTYGHFPSR AIKSEYPDPY TSSPESIMGY SYMDSYQTSS PASIPHLILE LLKCEPDEPQ VQAKIMAYLQ QEQANRSKHE KLSTFGLMCK MADQTLFSIV EWARSSIFFR ELKVDDQMKL LQNCWSELLI LDHIYRQVVH GKEGSIFLVT GQQVDYSIIA SQAGATLNNL MSHAQELVAK LRSLQFDQRE FVCLKFLVLF SLDVKNLENF QLVEGVQEQV NAALLDYTMC NYPQQTEKFG QLLLRLPEIR AISMQAEEYL YYKHLNGDVP YNNLLIEMLH AKRA |
Entity #1885 | Name: PGC1 alpha / Type: protein Description: Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Formula weight: 1.522 / Num. of mol.: 1 / Source: Homo sapiens Sequence: EEPSLLKKLL LAPA |
Entity #1886 | Type: DNA / Description: CYP7A1 Promoter Forward / Formula weight: 3.75 / Num. of mol.: 1 / Source: Homo sapiens Sequence: GTTCAAGGCC AG |
Entity #1887 | Type: DNA / Description: CYP7A1 Promoter Reverse / Formula weight: 3.701 / Num. of mol.: 1 / Source: Homo sapiens Sequence: CTGGCCTTGA AC |
-Experimental information
Beam | Instrument name: Advanced Light Source (ALS) 12.3.1 (SIBYLS) City: Berkeley, CA / 国: USA ![]() | |||||||||||||||||||||||||||||||||
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Detector | Name: Pilatus3 X 2M / Pixsize x: 172 mm | |||||||||||||||||||||||||||||||||
Scan | Measurement date: May 26, 2019 / Cell temperature: 20 °C / Exposure time: 3 sec. / Number of frames: 500 / Unit: 1/A /
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Distance distribution function P(R) |
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Result |
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