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- SASDFW9: Adhesion G-protein coupled receptor G6 - hGPR126 S2 (-ss) ECR -

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ID or keywords:

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Basic information

Entry
Database: SASBDB / ID: SASDFW9
SampleAdhesion G-protein coupled receptor G6 - hGPR126 S2 (-ss) ECR
  • Adhesion G-protein coupled receptor G6 S2 (protein), GPR126, Homo sapiens
Function / homology
Function and homology information


Schwann cell differentiation / EGR2 and SOX10-mediated initiation of Schwann cell myelination / myelination in peripheral nervous system / heart trabecula formation / extracellular matrix binding / plasma membrane => GO:0005886 / laminin binding / collagen binding / myelination / cAMP-mediated signaling ...Schwann cell differentiation / EGR2 and SOX10-mediated initiation of Schwann cell myelination / myelination in peripheral nervous system / heart trabecula formation / extracellular matrix binding / plasma membrane => GO:0005886 / laminin binding / collagen binding / myelination / cAMP-mediated signaling / G protein-coupled receptor activity / adenylate cyclase-activating G protein-coupled receptor signaling pathway / nervous system development / endopeptidase activity / membrane => GO:0016020 / cell surface receptor signaling pathway / G protein-coupled receptor signaling pathway / endoplasmic reticulum membrane / cell surface / plasma membrane / cytoplasm
Similarity search - Function
Pentaxin family / Pentraxin / C-reactive protein / pentaxin family / Pentraxin-related / Pentraxin (PTX) domain profile. / GAIN domain superfamily / GPCR proteolysis site, GPS, motif / GPS motif / GAIN-B domain profile. / G-protein-coupled receptor proteolytic site domain / CUB domain ...Pentaxin family / Pentraxin / C-reactive protein / pentaxin family / Pentraxin-related / Pentraxin (PTX) domain profile. / GAIN domain superfamily / GPCR proteolysis site, GPS, motif / GPS motif / GAIN-B domain profile. / G-protein-coupled receptor proteolytic site domain / CUB domain / Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein. / CUB domain / CUB domain profile. / Spermadhesin, CUB domain superfamily / G-protein coupled receptors family 2 signature 2. / GPCR, family 2, secretin-like, conserved site / GPCR, family 2, secretin-like / 7 transmembrane receptor (Secretin family) / GPCR, family 2-like / G-protein coupled receptors family 2 profile 2. / Concanavalin A-like lectin/glucanase domain superfamily
Similarity search - Domain/homology
Adhesion G-protein coupled receptor G6
Similarity search - Component
Biological speciesHomo sapiens (human)
Contact author
  • Katherine Leon (Uchicago, The University of Chicago, Edward H. Levi Hall 5801 South Ellis Avenue Chicago, Illinois 60637 773.702.1234)

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Structure visualization

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Models

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Sample

SampleName: Adhesion G-protein coupled receptor G6 - hGPR126 S2 (-ss) ECR
Specimen concentration: 4.2 mg/ml
BufferName: 150 mM NaCl, 20 mM HEPES / pH: 7.5
Entity #1780Name: GPR126 / Type: protein / Description: Adhesion G-protein coupled receptor G6 S2 / Formula weight: 88.443 / Num. of mol.: 1 / Source: Homo sapiens / References: UniProt: Q86SQ4
Sequence: ASTSCRVVLS NPSGTFTSPC YPNDYPNSQA CMWTLRAPTG YIIQITFNDF DIEEAPNCIY DSLSLDNGES QTKFCGATAK GLSFNSSANE MHVSFSSDFS IQKKGFNASY IRVAVSLRNQ KVILPQTSDA YQVSVAKSIS IPELSAFTLC FEATKVGHED SDWTAFSYSN ...Sequence:
ASTSCRVVLS NPSGTFTSPC YPNDYPNSQA CMWTLRAPTG YIIQITFNDF DIEEAPNCIY DSLSLDNGES QTKFCGATAK GLSFNSSANE MHVSFSSDFS IQKKGFNASY IRVAVSLRNQ KVILPQTSDA YQVSVAKSIS IPELSAFTLC FEATKVGHED SDWTAFSYSN ASFTQLLSFG KAKSGYFLSI SDSKCLLNNA LPVKEKEDIF AESFEQLCLV WNNSLGSIGV NFKRNYETVP CDSTISKVIP GNGKLLLGSN QNEIVSLKGD IYNFRLWNFT MNAKILSNLS CNVKGNVVDW QNDFWNIPNL ALKAESNLSC GSYLIPLPAA ELASCADLGT LCQDGIIYRI SVVIQNILRH PEVKVQSKVA EWLNSTFQNW NYTVYVVNIS FHLSAGEDKI KVKRSLEDEP RLVLWALLVY NATNNTNLEG KIIQQKLLKN NESLDEGLRL HTVNVRQLGH CLAMEEPKGY YWPSIQPSEY VLPCPDKPGF SASRICFYNA TNPLVTYWGP VDISNCLKEA NEVANQILNL TADGQNLTSA NITNIVEQVK RIVNKEENID ITLGSTLMNI FSNILSSSDS DLLESSSEAL KTIDELAFKI DLNSTSHVNI TTRNLALSVS SLLPGTNAIS NFSIGLPSNN ESYFQMDFES GQVDPLASVI LPPNLLENLS PEDSVLVRRA QFTFFNKTGL FQDVGPQRKT LVSYVMACSI GNITIQNLKD PVQIKIKHTR TQEVHHPICA FWDLNKNKSF GGWNTSGCVA HRDSDASETV CLCNHFTHFG VLMDLPRSHH HHHHHH

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Experimental information

BeamInstrument name: Advanced Photon Source (APS), Argonne National Laboratory BioCAT 18ID
City: Lemont, IL / : USA / Type of source: X-ray synchrotron / Wavelength: 0.103 Å / Dist. spec. to detc.: 1 mm
DetectorName: Pilatus3 X 1M / Pixsize x: 0.172 mm
Scan
Title: Adhesion G-protein coupled receptor G6 - hGPR126 S2 (-ss) ECR
Measurement date: Jun 28, 2018 / Storage temperature: 4 °C / Cell temperature: 22 °C / Exposure time: 0.8 sec. / Number of frames: 1234 / Unit: 1/A /
MinMax
Q0.0052 0.3816
Distance distribution function P(R)
Sofotware P(R): GNOM 4.5a / Number of points: 275 /
MinMax
Q0.01024 0.1777
P(R) point16 290
R0 157
Result
Type of curve: sec /
ExperimentalPorod
MW117.8 kDa125 kDa
Volume-199 nm3

P(R)GuinierGuinier error
Forward scattering, I0126.1 124.1835 0.463
Radius of gyration, Rg4.61 nm4.409 nm0.238

MinMax
D-15.7
Guinier point22 82

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