+Open data
-Basic information
Entry | Database: SASBDB / ID: SASDFU7 |
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Sample | Talin-1 head amino acids 1-405(Δ134-170/GAG insert)
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Function / homology | Function and homology information LIM domain binding / vinculin binding / XBP1(S) activates chaperone genes / SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion / integrin activation / cell-substrate junction assembly / cell-cell junction assembly / cortical actin cytoskeleton organization / regulation of focal adhesion assembly / p130Cas linkage to MAPK signaling for integrins ...LIM domain binding / vinculin binding / XBP1(S) activates chaperone genes / SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion / integrin activation / cell-substrate junction assembly / cell-cell junction assembly / cortical actin cytoskeleton organization / regulation of focal adhesion assembly / p130Cas linkage to MAPK signaling for integrins / phosphatidylserine binding / GRB2:SOS provides linkage to MAPK signaling for Integrins / Smooth Muscle Contraction / ruffle / Integrin signaling / phosphatidylinositol binding / integrin-mediated signaling pathway / adherens junction / Signaling by high-kinase activity BRAF mutants / MAP2K and MAPK activation / structural constituent of cytoskeleton / platelet aggregation / ruffle membrane / cell-cell adhesion / Signaling by RAF1 mutants / Signaling by moderate kinase activity BRAF mutants / Paradoxical activation of RAF signaling by kinase inactive BRAF / Signaling downstream of RAS mutants / Signaling by BRAF and RAF1 fusions / actin filament binding / integrin binding / Platelet degranulation / cytoskeleton / cadherin binding / focal adhesion / cell surface / extracellular exosome / extracellular region / plasma membrane / cytosol Similarity search - Function |
Biological species | Homo sapiens (human) |
Contact author |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Data source
SASBDB page | SASDFU7 |
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-Related structure data
Similar structure data | Similarity search - Function & homologyF&H Search |
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-External links
Related items in Molecule of the Month |
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-Models
Model #3067 | Type: mix / Radius of dummy atoms: 1.90 A / Symmetry: P1 / Chi-square value: 2.046 / P-value: 0.348480 |
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Model #3068 | Type: mix / Software: (2.1 online) / Radius of dummy atoms: 1.90 A / Symmetry: P1 / Chi-square value: 2.046 / P-value: 0.348480 |
Model #3069 | Type: mix / Radius of dummy atoms: 1.90 A / Symmetry: P1 / Chi-square value: 2.046 / P-value: 0.348480 |
-Sample
Sample | Name: Talin-1 head amino acids 1-405(Δ134-170/GAG insert) / Specimen concentration: 8.17 mg/ml |
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Buffer | Name: 50 mM sodium phosphate, 150mM NaCl / pH: 7.2 |
Entity #1685 | Name: TLN1 / Type: protein / Description: Talin-1 (Δ134-170/GAG insert), human / Formula weight: 46.962 / Num. of mol.: 1 / Source: Homo sapiens / References: UniProt: Q9Y490 Sequence: GGSHHHHHHG MASMTGGQQM GRDLYDDDDK DRWIRPRAMV ALSLKISIGN VVKTMQFEPS TMVYDACRII RERIPEAPAG PPSDFGLFLS DDDPKKGIWL EAGKALDYYM LRNGDTMEYR KKQRPLKIRM LDGTVKTIMV DDSKTVTDML MTICARIGIT NHDEYSLVRE ...Sequence: GGSHHHHHHG MASMTGGQQM GRDLYDDDDK DRWIRPRAMV ALSLKISIGN VVKTMQFEPS TMVYDACRII RERIPEAPAG PPSDFGLFLS DDDPKKGIWL EAGKALDYYM LRNGDTMEYR KKQRPLKIRM LDGTVKTIMV DDSKTVTDML MTICARIGIT NHDEYSLVRE LGAGLNWLDH GRTLREQGVE EHETLLLRRK FFYSDQNVDS RDPVQLNLLY VQARDDILNG SHPVSFDKAC EFAGFQCQIQ FGPHNEQKHK AGFLDLKDFL PKEYVKQKGE RKIFQAHKNC GQMSEIEAKV RYVKLARSLK TYGVSFFLVK EKMKGKNKLV PRLLGITKEC VMRVDEKTKE VIQEWNLTNI KRWAASPKSF TLDFGDYQDG YYSVQTTEGE QIAQLIAGYI DIILKKKKS |
-Experimental information
Beam | Instrument name: PETRA III EMBL P12 / City: Hamburg / 国: Germany / Type of source: X-ray synchrotron / Wavelength: 0.12399 Å / Dist. spec. to detc.: 3 mm | |||||||||||||||||||||||||||||||||
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Detector | Name: Pilatus 2M | |||||||||||||||||||||||||||||||||
Scan | Title: Talin-1 head amino acids 1-405(Δ134-170/GAG insert) / Measurement date: Sep 24, 2015 / Storage temperature: 4 °C / Cell temperature: 10 °C / Exposure time: 0.995 sec. / Number of frames: 20 / Unit: 1/nm /
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Distance distribution function P(R) | Sofotware P(R): GNOM 5.0 / Number of points: 957 /
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Result | Type of curve: sec
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