+Open data
-Basic information
Entry | Database: SASBDB / ID: SASDCW4 |
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Sample | Bovine β Cardiac Myosin S1 fragment (Myosin-7) MgADP.VO4+OM
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Function / homology | Function and homology information muscle filament sliding / myosin filament / adult heart development / myosin II complex / sarcomere organization / microfilament motor activity / myofibril / cardiac muscle contraction / sarcomere / actin filament binding ...muscle filament sliding / myosin filament / adult heart development / myosin II complex / sarcomere organization / microfilament motor activity / myofibril / cardiac muscle contraction / sarcomere / actin filament binding / calmodulin binding / ATP binding / cytoplasm Similarity search - Function |
Biological species | Bos taurus (cattle) |
Citation | Date: 2017 Dec Title: Mechanistic and structural basis for activation of cardiac myosin force production by omecamtiv mecarbil Authors: Planelles-Herrero V / Hartman J / Robert-Paganin J / Malik F |
Contact author |
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-Structure visualization
-Downloads & links
-Data source
SASBDB page | SASDCW4 |
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-Related structure data
Related structure data | C: citing same article (ref.) |
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Similar structure data | Similarity search - Function & homologyF&H Search |
-External links
Related items in Molecule of the Month |
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-Models
-Sample
Sample | Name: Bovine β Cardiac Myosin S1 fragment (Myosin-7) MgADP.VO4+OM Specimen concentration: 4 mg/ml |
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Buffer | Name: 10 mM HEPES, 50 mM NaCl, 1 mM NaN3, 2.5 mM MgCl2, 2 mM ADP, 1 mM TCEP pH: 7.5 |
Entity #621 | Name: BCS1 (myosin-7) / Type: protein / Description: Bovine β Cardiac Myosin S1 fragment / Formula weight: 116.582 / Num. of mol.: 1 / Source: Bos taurus / References: UniProt: Q9BE39 Sequence: MVDAEMAAFG EAAPYLRKSE KERLEAQTRP FDLKKDVFVP DDKEEFVKAT ILSREGGKVT AETEHGKTVT VKEDQVLQQN PPKFDKIEDM AMLTFLHEPA VLYNLKERYA SWMIYTYSGL FCVTINPYKW LPVYNAEVVA AYRGKKRSEA PPHIFSISDN AYQYMLTDRE ...Sequence: MVDAEMAAFG EAAPYLRKSE KERLEAQTRP FDLKKDVFVP DDKEEFVKAT ILSREGGKVT AETEHGKTVT VKEDQVLQQN PPKFDKIEDM AMLTFLHEPA VLYNLKERYA SWMIYTYSGL FCVTINPYKW LPVYNAEVVA AYRGKKRSEA PPHIFSISDN AYQYMLTDRE NQSILITGES GAGKTVNTKR VIQYFAVIAA IGDRSKKEQA TGKGTLEDQI IQANPALEAF GNAKTVRNDN SSRFGKFIRI HFGATGKLAS ADIETYLLEK SRVIFQLKAE RDYHIFYQIL SNKKPELLDM LLITNNPYDY AFISQGETTV ASIDDAEELM ATDNAFDVLG FTTEEKNSMY KLTGAIMHFG NMKFKLKQRE EQAEPDGTEE ADKSAYLMGL NSADLLKGLC HPRVKVGNEY VTKGQNVQQV VYAKGALAKA VYERMFNWMV TRINATLETK QPRQYFIGVL DIAGFEIFDF NSFEQLCINF TNEKLQQFFN HHMFVLEQEE YKKEGIEWEF IDFGMDLQAC IDLIEKPMGI MSILEEECMF PKATDMTFKA KLFDNHLGKS SNFQKPRNIK GKPEAHFSLI HYAGTVDYNI IGWLQKNKDP LNETVVDLYK KSSLKMLSSL FANYAGFDTP IEKGKGKAKK GSSFQTVSAL HRENLNKLMT NLRSTHPHFV RCIIPNETKS PGVIDNPLVM HQLRCNGVLE GIRICRKGFP NRILYGDFRQ RYRILNPAAI PEGQFIDSRK GAEKLLGSLD IDHNQYKFGH TKVFFKAGLL GLLEEMRDER LSRIITRIQA QSRGVLSRME FKKLLERRDS LLIIQWNIRA FMGVKNWPMA PKKPDPKKDE AKAGAKAAAA PAPAPAPPPA PEPSKEPEFD PSKIKIEFTP EQIEEFKEAF TLFDRTPKCE MKITYGQCGD VLRALGQNPT QAEVLRVLGK PKQEELNSKM MDFDTFLPML QHISKNKDTG TYEDFVEGLR VFDKEGNGTV MGAELRHVLA TLGEKLTEDE VEKLMAGQED SNGCINYEAF VKHIMAG |
-Experimental information
Beam | Instrument name: SOLEIL SWING / City: Saint-Aubin / 国: France / Type of source: X-ray synchrotron / Wavelength: 0.10332 Å / Dist. spec. to detc.: 1.786 mm | ||||||||||||||||||||||||||||||||||||
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Detector | Name: AVIEX / Type: CCD | ||||||||||||||||||||||||||||||||||||
Scan | Title: Bovine β Cardiac Myosin S1 fragment (Myosin-7) MgADP.VO4+OM Measurement date: Mar 1, 2016 / Storage temperature: 4 °C / Exposure time: 0.5 sec. / Number of frames: 41 / Unit: 1/A /
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Distance distribution function P(R) | Sofotware P(R): GNOM 5.0 / Number of points: 264 /
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Result | Type of curve: single_conc / Comments: BATCH mode
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