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- SASDCP8: Ras-related protein Rab-1A (Rab1a) -

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ID or keywords:

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Basic information

Entry
Database: SASBDB / ID: SASDCP8
SampleRas-related protein Rab-1A
  • Ras-related protein Rab-1A (protein), Rab1a, Homo sapiens
Function / homology
Function and homology information


interleukin-8 production => GO:0032637 / : / positive regulation of glycoprotein metabolic process / growth hormone secretion / Rab protein signal transduction / COPII-coated vesicle cargo loading / melanosome transport / COPII vesicle coating / vesicle transport along microtubule / RAB geranylgeranylation ...interleukin-8 production => GO:0032637 / : / positive regulation of glycoprotein metabolic process / growth hormone secretion / Rab protein signal transduction / COPII-coated vesicle cargo loading / melanosome transport / COPII vesicle coating / vesicle transport along microtubule / RAB geranylgeranylation / positive regulation of ubiquitin protein ligase activity / RAB GEFs exchange GTP for GDP on RABs / retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum / Golgi Cisternae Pericentriolar Stack Reorganization / COPII-mediated vesicle transport / COPI-dependent Golgi-to-ER retrograde traffic / transport vesicle membrane / virion assembly / Golgi organization / autophagosome assembly / endoplasmic reticulum to Golgi vesicle-mediated transport / COPI-mediated anterograde transport / vesicle-mediated transport / post-translational protein modification / substrate adhesion-dependent cell spreading / intracellular protein transport / autophagy / endocytosis / melanosome / cell migration / early endosome / defense response to bacterium / cadherin binding / Golgi membrane / GTPase activity / GTP binding / endoplasmic reticulum / Golgi apparatus / extracellular exosome / cytosol
Similarity search - Function
small GTPase Rab1 family profile. / Small GTPase / Ras family / Small GTP-binding protein domain / P-loop containing nucleoside triphosphate hydrolase
Similarity search - Domain/homology
Ras-related protein Rab-1A
Similarity search - Component
Biological speciesHomo sapiens (human)
Contact author
  • Wenhua Zhang (CNRS UMR8113, ENS Paris-Saclay)

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Structure visualization

Structure viewerMolecule:
MolmilJmol/JSmol

Downloads & links

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Models

Model #1616
Type: dummy / Software: (2.8.2) / Radius of dummy atoms: 1.40 A / Symmetry: P1 / Chi-square value: 1.745 / P-value: 0.000005

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Sample

SampleName: Ras-related protein Rab-1A / Specimen concentration: 2.00-6.00
BufferName: 300 mM NaCl, 2 mM 2-mercaptoethanol and 30 mM Tris-HCl
pH: 7.5
Entity #845Name: Rab1a / Type: protein / Description: Ras-related protein Rab-1A / Formula weight: 23.5 / Num. of mol.: 1 / Source: Homo sapiens / References: UniProt: P62820.3
Sequence: MSSMNPEYDY LFKLLLIGDS GVGKSCLLLR FADDTYTESY ISTIGVDFKI RTIELDGKTI KLQIWDTAGQ ERFRTITSSY YRGAHGIIVV YDVTDQESFN NVKQWLQEID RYASENVNKL LVGNKCDLTT KKVVDYTTAK EFADSLGIPF LETSAKNATN VEQSFMTMAA ...Sequence:
MSSMNPEYDY LFKLLLIGDS GVGKSCLLLR FADDTYTESY ISTIGVDFKI RTIELDGKTI KLQIWDTAGQ ERFRTITSSY YRGAHGIIVV YDVTDQESFN NVKQWLQEID RYASENVNKL LVGNKCDLTT KKVVDYTTAK EFADSLGIPF LETSAKNATN VEQSFMTMAA EIKKRMGPGA TAGGAEKSNV KIQSTPVKQS GGGCCHHHHH H

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Experimental information

BeamInstrument name: SOLEIL SWING / City: Saint-Aubin / : France / Type of source: X-ray synchrotron / Wavelength: 0.103 Å / Dist. spec. to detc.: 1.2 mm
DetectorName: AVIEX / Type: CCD
Scan
Title: Ras-related protein Rab-1A / Measurement date: Nov 17, 2015 / Cell temperature: 15 °C / Exposure time: 1.2 sec. / Number of frames: 240 / Unit: 1/A /
MinMax
Q0.0169 0.6125
Distance distribution function P(R)
Sofotware P(R): GNOM 5.0 / Number of points: 350 /
MinMax
Q0.0169059 0.21348
P(R) point1 350
R0 102
Result
Type of curve: single_conc /
ExperimentalPorod
MW24 kDa24 kDa
Volume-36.1 nm3

P(R)P(R) errorGuinierGuinier error
Forward scattering, I00.01385 1.4E-5 0.01366 1.3E-5
Radius of gyration, Rg2.54 nm0.006 2.38 nm0.004

MinMax
D-10.2
Guinier point11 59

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