+Open data
-Basic information
Entry | Database: PDB chemical components / ID: QEL | ||||
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Name | Name: Synonyms: Ifenprodil Wikipedia | Wikipedia - Ifenprodil: Ifenprodil is an inhibitor of the NMDA receptor, specifically of GluN1 (glycine-binding NMDA receptor subunit 1) and GluN2B (glutamate-binding NMDA receptor subunit 2) subunits. Additionally, ifenprodil inhibits GIRK channels, and interacts with alpha1 adrenergic, serotonin, and sigma receptors. | NMDA receptors are multimeric ionotropic glutamate receptors composed of four subunits... Comment | inhibitor*YM | |
-Chemical information
Composition | Formula: C21H27NO2 / Number of atoms: 51 / Formula weight: 325.445 / Formal charge: 0 | ||||||||
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Others | Type: NON-POLYMER / PDB classification: HETAIN / Three letter code: QEL / Ideal coordinates details: Corina | ||||||||
History |
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External links | UniChem / BindingDB / ChEMBL / Nikkaji / PubChem / SureChEMBL / ZINC / ChemSpider / Wikipedia search / Google search |
-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Details
-SMILES
ACDLabs 12.01 | CACTVS 3.370 | OpenEye OEToolkits 1.7.0 | |
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-SMILES CANONICAL
CACTVS 3.370 | OpenEye OEToolkits 1.7.0 | |
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-InChI
InChI 1.03 |
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-InChIKey
InChI 1.03 |
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-SYSTEMATIC NAME
ACDLabs 12.01 | OpenEye OEToolkits 1.7.0 | |
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-PDB entries
Showing all 4 items
PDB-3qel:
Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2B in complex with ifenprodil
PDB-4pe5:
Crystal Structure of GluN1a/GluN2B NMDA Receptor Ion Channel
PDB-5ewj:
CRYSTAL STRUCTURE OF AMINO TERMINAL DOMAINS OF THE NMDA RECEPTOR SUBUNIT GLUN1 AND GLUN2B IN COMPLEX WITH IFENPRODIL
PDB-7aqi:
Structure of SARS-CoV-2 Main Protease bound to Ifenprodil