RIBOSOME / Translation / co-translational protein processing
Function / homology
Function and homology information
negative regulation of protein localization to endoplasmic reticulum / nascent polypeptide-associated complex / negative regulation of striated muscle cell apoptotic process / [histone H4]-N-methyl-L-lysine20 N-methyltransferase / regulation of skeletal muscle fiber development / positive regulation of cell proliferation involved in heart morphogenesis / myristoyltransferase activity / N-terminal peptidyl-glycine N-myristoylation / peptidyl-lysine N6-myristoyltransferase activity / [histone H4]-lysine20 N-methyltransferase ...negative regulation of protein localization to endoplasmic reticulum / nascent polypeptide-associated complex / negative regulation of striated muscle cell apoptotic process / [histone H4]-N-methyl-L-lysine20 N-methyltransferase / regulation of skeletal muscle fiber development / positive regulation of cell proliferation involved in heart morphogenesis / myristoyltransferase activity / N-terminal peptidyl-glycine N-myristoylation / peptidyl-lysine N6-myristoyltransferase activity / [histone H4]-lysine20 N-methyltransferase / Late Phase of HIV Life Cycle / positive regulation of skeletal muscle tissue growth / histone H4K20 methyltransferase activity / ketone metabolic process / regulation of opsin-mediated signaling pathway / cardiac ventricle development / Activation, myristolyation of BID and translocation to mitochondria / positive regulation of establishment of protein localization to mitochondrion / glycylpeptide N-tetradecanoyltransferase / glycylpeptide N-tetradecanoyltransferase activity / heart trabecula morphogenesis / skeletal muscle tissue regeneration / S-adenosyl-L-methionine binding / protein localization to membrane / ribosomal subunit / exit from mitosis / optic nerve development / laminin receptor activity / retinal ganglion cell axon guidance / positive regulation of double-strand break repair via nonhomologous end joining / Peptide chain elongation / Selenocysteine synthesis / Formation of a pool of free 40S subunits / ubiquitin ligase inhibitor activity / Eukaryotic Translation Termination / positive regulation of signal transduction by p53 class mediator / Response of EIF2AK4 (GCN2) to amino acid deficiency / SRP-dependent cotranslational protein targeting to membrane / Viral mRNA Translation / Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) / 90S preribosome / GTP hydrolysis and joining of the 60S ribosomal subunit / L13a-mediated translational silencing of Ceruloplasmin expression / phagocytic cup / Major pathway of rRNA processing in the nucleolus and cytosol / protein-RNA complex assembly / pericentric heterochromatin / Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) / maturation of LSU-rRNA / ribosomal small subunit export from nucleus / laminin binding / rough endoplasmic reticulum / eNOS activation / translation regulator activity / gastrulation / cytosolic ribosome / MDM2/MDM4 family protein binding / Transferases; Acyltransferases; Transferring groups other than aminoacyl groups / class I DNA-(apurinic or apyrimidinic site) endonuclease activity / DNA-(apurinic or apyrimidinic site) lyase / cellular response to interleukin-4 / maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / ribosomal large subunit biogenesis / positive regulation of apoptotic signaling pathway / maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / maturation of SSU-rRNA / small-subunit processome / wound healing / spindle / Regulation of expression of SLITs and ROBOs / cytoplasmic ribonucleoprotein granule / antimicrobial humoral immune response mediated by antimicrobial peptide / rRNA processing / rhythmic process / positive regulation of canonical Wnt signaling pathway / Inactivation, recovery and regulation of the phototransduction cascade / protein transport / large ribosomal subunit / regulation of translation / heparin binding / ribosome binding / virus receptor activity / ribosomal small subunit biogenesis / ribosomal small subunit assembly / retina development in camera-type eye / small ribosomal subunit / ribosomal large subunit assembly / cytosolic small ribosomal subunit / large ribosomal subunit rRNA binding / small ribosomal subunit rRNA binding / defense response to Gram-negative bacterium / methylation / killing of cells of another organism / cytosolic large ribosomal subunit / in utero embryonic development / perikaryon / cytoplasmic translation / cell differentiation / transcription coactivator activity / tRNA binding Similarity search - Function
Transcription factor BTF3 / Nascent polypeptide-associated complex NAC domain / Nascent polypeptide-associated complex subunit alpha / Suv4-20 family, animal / NAC A/B domain superfamily / Histone-lysine N-methyltransferase Suv4-20/Set9 / Histone-lysine N-methyltransferase, N-terminal domain / NAC domain / NAC A/B domain profile. / Histone-lysine N-methyltransferase (EC 2.1.1.43) family profile. ...Transcription factor BTF3 / Nascent polypeptide-associated complex NAC domain / Nascent polypeptide-associated complex subunit alpha / Suv4-20 family, animal / NAC A/B domain superfamily / Histone-lysine N-methyltransferase Suv4-20/Set9 / Histone-lysine N-methyltransferase, N-terminal domain / NAC domain / NAC A/B domain profile. / Histone-lysine N-methyltransferase (EC 2.1.1.43) family profile. / NAC / Nascent polypeptide-associated complex subunit alpha-like, UBA domain / HYPK UBA domain / Glycylpeptide N-tetradecanoyltransferase, conserved site / Myristoyl-CoA:protein N-myristoyltransferase signature 1. / Myristoyl-CoA:protein N-myristoyltransferase signature 2. / Glycylpeptide N-tetradecanoyltransferase / Glycylpeptide N-tetradecanoyltransferase, N-terminal / Glycylpeptide N-tetradecanoyltransferase, C-terminal / Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain / Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain / Ribosomal protein L19e, C-terminal domain / 60s Acidic ribosomal protein / 60S acidic ribosomal protein P0 / : / 40S ribosomal protein SA / 40S ribosomal protein SA, C-terminal domain / 40S ribosomal protein SA C-terminus / Ribosomal protein L6, N-terminal / Ribosomal protein L6, N-terminal domain / Ubiquitin-like protein FUBI / Ribosomal protein L30e / Ribosomal protein L2, archaeal-type / Ribosomal L15/L27a, N-terminal / SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain / 50S ribosomal protein L10, insertion domain superfamily / Ribosomal protein L23 / SET domain / 60S ribosomal protein L10P, insertion domain / Insertion domain in 60S ribosomal protein L10P / Ribosomal L28e/Mak16 / Ribosomal L28e protein family / SET domain superfamily / SET domain profile. / SET domain / metallochaperone-like domain / TRASH domain / : / Ribosomal protein S26e signature. / Ribosomal protein L41 / Ribosomal protein L41 / Ribosomal protein S21e, conserved site / Ribosomal protein S21e signature. / Ribosomal protein S26e / Ribosomal protein S26e superfamily / Ribosomal protein S26e / Ribosomal protein L1, conserved site / : / Ribosomal protein S12e signature. / Ribosomal protein L1 signature. / Ribosomal protein S12e / Ribosomal protein L1 / Ribosomal protein L29e / Ribosomal L29e protein family / Ribosomal protein S19e, conserved site / Ribosomal protein S19e signature. / Small (40S) ribosomal subunit Asc1/RACK1 / Ribosomal protein S5, eukaryotic/archaeal / Ribosomal protein S21e / Ribosomal protein S21e superfamily / Ribosomal protein S21e / Ribosomal protein S2, eukaryotic / S27a-like superfamily / Ribosomal protein L22e / Ribosomal protein L22e superfamily / Ribosomal L22e protein family / Ribosomal protein L10e, conserved site / Ribosomal protein L10e signature. / Ribosomal protein L27e, conserved site / Ribosomal protein L27e signature. / Ribosomal protein L10e / 40S Ribosomal protein S10 / Ribosomal protein L38e / Ribosomal protein L38e superfamily / Ribosomal L38e protein family / : / Ribosomal protein S7e signature. / Ribosomal protein L44e signature. / Plectin/S10, N-terminal / Plectin/S10 domain / Ribosomal protein L1, 3-layer alpha/beta-sandwich / Ribosomal protein L24e, conserved site / Ribosomal protein L24e signature. / : / Ribosomal protein S10, eukaryotic/archaeal / Ribosomal protein L19, eukaryotic / Ribosomal protein L19/L19e conserved site / Ribosomal protein L19e signature. / Ribosomal protein L6e signature. / Ribosomal protein L13e Similarity search - Domain/homology
SPERMIDINE / SPERMINE / : / : / : / RNA / RNA (> 10) / RNA (> 100) / RNA (> 1000) / Small ribosomal subunit protein eS32 ...SPERMIDINE / SPERMINE / : / : / : / RNA / RNA (> 10) / RNA (> 100) / RNA (> 1000) / Small ribosomal subunit protein eS32 / 40S ribosomal protein S26 / Large ribosomal subunit protein eL28 / Ribosomal protein L32 / 60S ribosomal protein L36a-like / Large ribosomal subunit protein uL16 / Small ribosomal subunit protein uS4 / Large ribosomal subunit protein uL15/eL18 domain-containing protein / Large ribosomal subunit protein uL22 / Large ribosomal subunit protein eL24 / Large ribosomal subunit protein uL23 / Large ribosomal subunit protein eL33 / Small ribosomal subunit protein eS12 / Large ribosomal subunit protein eL29 / Small ribosomal subunit protein uS9 / Large ribosomal subunit protein eL31 / Large ribosomal subunit protein eL21 / Large ribosomal subunit protein uL29 / Small ribosomal subunit protein uS10 / Small ribosomal subunit protein RACK1 / Ubiquitin-ribosomal protein eS31 fusion protein / Large ribosomal subunit protein eL6 / Large ribosomal subunit protein uL1 / Large ribosomal subunit protein uL11 / Large ribosomal subunit protein uL15 / Small ribosomal subunit protein uS15 / Large ribosomal subunit protein uL10 / Large ribosomal subunit protein uL24 / Small ribosomal subunit protein eS1 / Small ribosomal subunit protein eS7 / Large ribosomal subunit protein uL4 / Large ribosomal subunit protein uL6 / Large ribosomal subunit protein eL43 / Large ribosomal subunit protein eL14 / Small ribosomal subunit protein uS12 / Large ribosomal subunit protein eL15 / Small ribosomal subunit protein uS11 / 40S ribosomal protein S24 / Large ribosomal subunit protein uL14 / Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein / Small ribosomal subunit protein eS25 / Large ribosomal subunit protein eL30 / Small ribosomal subunit protein uS7 / Small ribosomal subunit protein uS8 / Small ribosomal subunit protein eS28 / Ribosomal protein L19 / Small ribosomal subunit protein eS8 / Small ribosomal subunit protein eS4 / Large ribosomal subunit protein eL13 / Large ribosomal subunit protein uL3 / Small ribosomal subunit protein uS2 / Small ribosomal subunit protein eS6 / Small ribosomal subunit protein eS21 / Small ribosomal subunit protein eS19 / Small ribosomal subunit protein uS3 / Small ribosomal subunit protein uS13 / Small ribosomal subunit protein eS10 / Small ribosomal subunit protein uS17 / Large ribosomal subunit protein eL22 / Large ribosomal subunit protein uL2 / Large ribosomal subunit protein eL39 / Large ribosomal subunit protein eL36 / Large ribosomal subunit protein eL20 / Small ribosomal subunit protein eS17 / Large ribosomal subunit protein uL30 / Large ribosomal subunit protein uL5 / Large ribosomal subunit protein uL13 / Large ribosomal subunit protein eL27 / Large ribosomal subunit protein eL34 / Small ribosomal subunit protein eS27 / Large ribosomal subunit protein eL38 / Small ribosomal subunit protein uS19 / Small ribosomal subunit protein uS14 / Small ribosomal subunit protein uS5 / Ubiquitin-ribosomal protein eL40 fusion protein / Transcription factor BTF3 / Glycylpeptide N-tetradecanoyltransferase 1 / Large ribosomal subunit protein eL8 / Nascent polypeptide-associated complex subunit alpha / Large ribosomal subunit protein eL37 Similarity search - Component
Biological species
Homo sapiens (human) Oryctolagus cuniculus (rabbit)
Method
ELECTRON MICROSCOPY / single particle reconstruction / cryo EM / Resolution: 2.8 Å
A2: 18S rRNA AA: Small ribosomal subunit protein eS27 AB: Small ribosomal subunit protein eS28 AC: Ubiquitin-ribosomal protein eS31 fusion protein AD: Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein AE: eS26 AF: Small ribosomal subunit protein RACK1 AG: Small ribosomal subunit protein uS14 AT: P site Phe tRNA AZ: Small ribosomal subunit protein uS2 Aa: 40S ribosomal protein S3a Ab: 40S ribosomal protein S2 Ac: 40S ribosomal protein S3 Ad: 40S ribosomal protein S4 Ae: Small ribosomal subunit protein uS7 Af: 40S ribosomal protein S6 Ag: 40S ribosomal protein S7 Ah: 40S ribosomal protein S8 Ai: Small ribosomal subunit protein uS4 Aj: S10_plectin domain-containing protein Ak: Small ribosomal subunit protein uS17 Al: Small ribosomal subunit protein eS12 Am: Small ribosomal subunit protein uS15 An: Small ribosomal subunit protein uS11 Ao: Small ribosomal subunit protein uS19 Ap: Small ribosomal subunit protein uS9 Aq: Small ribosomal subunit protein eS17 Ar: Small ribosomal subunit protein uS13 As: 40S ribosomal protein S19 At: Small ribosomal subunit protein uS10 Au: Small ribosomal subunit protein eS21 Av: Small ribosomal subunit protein uS8 Aw: 40S ribosomal protein S23 Ax: 40S ribosomal protein S24 Ay: Small ribosomal subunit protein eS25 Az: Small ribosomal subunit protein eS32 B5: 28S rRNA B7: 5S rRNA B8: 5.8S rRNA BA: Large ribosomal subunit protein uL2 BB: Ribosomal protein L3 BC: Large ribosomal subunit protein uL4 BE: 60S ribosomal protein L6 BF: Ribosomal Protein uL30 BG: 60S ribosomal protein L7a BH: 60S ribosomal protein L9 BI: 60S ribosomal protein L10 BJ: 60S ribosomal protein L11 BK: Nascent chain BL: Large ribosomal subunit protein eL13 BM: 60S ribosomal protein L14 BN: Ribosomal protein L15 BO: Large ribosomal subunit protein uL13 BP: Large ribosomal subunit protein uL22 BQ: eL18 BR: Ribosomal protein L19 BS: Large ribosomal subunit protein eL20 BT: 60S ribosomal protein L21 BU: 60S ribosomal protein L22 BV: Ribosomal protein L23 BW: Ribosomal protein L24 BX: Large ribosomal subunit protein uL23 BY: Ribosomal protein L26 BZ: 60S ribosomal protein L27 Ba: 60S ribosomal protein L27a Bb: 60S ribosomal protein L29 Bc: 60S ribosomal protein L30 Bd: 60S ribosomal protein L31 Be: Ribosomal protein L32 Bf: 60S ribosomal protein L35a Bg: 60S ribosomal protein L34 Bh: 60S ribosomal protein L35 Bi: 60S ribosomal protein L36 Bj: Ribosomal protein L37 Bk: 60S ribosomal protein L38 Bl: 60S ribosomal protein L39-like Bm: Ubiquitin-ribosomal protein eL40 fusion protein Bo: Large ribosomal subunit protein eL42 Bp: 60S ribosomal protein L37a Br: [histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B Bs: Large ribosomal subunit protein uL10 Bt: 60S ribosomal protein L12 Bv: Ribosomal protein uL1 MA: Glycylpeptide N-tetradecanoyltransferase 1 Nt: Nascent polypeptide-associated complex subunit alpha Nu: Isoform 2 of Transcription factor BTF3 hetero molecules
Mass: 15697.503 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Oryctolagus cuniculus (rabbit) References: UniProt: A0A8C0DF35, [histone H4]-lysine20 N-methyltransferase, [histone H4]-N-methyl-L-lysine20 N-methyltransferase
#84: Protein
GlycylpeptideN-tetradecanoyltransferase1 / Myristoyl-CoA:protein N-myristoyltransferase 1 / HsNMT1 / NMT 1 / Type I N-myristoyltransferase / ...Myristoyl-CoA:protein N-myristoyltransferase 1 / HsNMT1 / NMT 1 / Type I N-myristoyltransferase / Peptide N-myristoyltransferase 1 / Protein-lysine myristoyltransferase NMT1
Mass: 56791.930 Da / Num. of mol.: 1 / Mutation: Y180A Source method: isolated from a genetically manipulated source Source: (gene. exp.) Homo sapiens (human) / Gene: NMT1, NMT / Production host: Escherichia coli (E. coli) References: UniProt: P30419, glycylpeptide N-tetradecanoyltransferase, Transferases; Acyltransferases; Transferring groups other than aminoacyl groups
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