EMDB-54639: Structure of human mitochondrial COX1-translating ribosome nascen...

Basic information

Entry

Database: EMDB / ID: EMD-54639

• Title: Structure of human mitochondrial COX1-translating ribosome nascent chain-OXA1L/MITRAC complex in open state (open COX1-mtRNC-OXA1L/MITRAC)

Sample

• Complex: Human mitochondrial 55S ribosome complex with tRNAs and COX1 nascent chain
  • RNA: x 6 types
  • Protein or peptide: x 79 types
• Protein or peptide: x 5 types
• Ligand: x 8 types

• Keywords: mt55S / ribosome / micochondria / COX1 / membrane / translation

Function / homology

Function:

mitochondrial protein quality control / negative regulation of oxidoreductase activity / mitochondrial ribosome binding / protein insertion into mitochondrial inner membrane from matrix / membrane insertase activity / Complex I biogenesis / negative regulation of ATP-dependent activity / mitochondrial transcription / rRNA import into mitochondrion / rescue of stalled mitochondrial ribosome / mitochondrial translational termination / mitochondrial translational elongation / translation release factor activity, codon nonspecific / mitochondrial proton-transporting ATP synthase complex assembly / mitochondrial ribosome assembly / Mitochondrial translation elongation / Mitochondrial translation initiation / Mitochondrial ribosome-associated quality control / Mitochondrial translation termination / mitochondrial large ribosomal subunit / peptidyl-tRNA hydrolase / mitochondrial ribosome / mitochondrial small ribosomal subunit / peptidyl-tRNA hydrolase activity / mitochondrial translation / ribosomal small subunit binding / positive regulation of proteolysis / mitochondrial respiratory chain complex I assembly / anatomical structure morphogenesis / RNA processing / Mitochondrial protein degradation / apoptotic signaling pathway / aerobic respiration / protein tetramerization / fibrillar center / cell population proliferation / mitochondrial membrane / regulation of translation / double-stranded RNA binding / 5S rRNA binding / small ribosomal subunit / small ribosomal subunit rRNA binding / large ribosomal subunit rRNA binding / Hydrolases; Acting on acid anhydrides; Acting on GTP to facilitate cellular and subcellular movement / tRNA binding / negative regulation of translation / mitochondrial inner membrane / rRNA binding / ribosome / translation / structural constituent of ribosome / mitochondrial matrix / ribonucleoprotein complex / protein domain specific binding / nucleotide binding / apoptotic process / mRNA binding / GTPase activity / positive regulation of DNA-templated transcription / GTP binding / protein homodimerization activity / protein-containing complex / mitochondrion / : / RNA binding / nucleoplasm / nucleus / cytoplasm

Domain/homology:

Ribosomal protein L1, mitochondrial / Membrane insertase YidC/Oxa1, C-terminal / 60Kd inner membrane protein / Membrane insertase YidC/ALB3/OXA1/COX18 / Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 / Cysteine alpha-hairpin motif superfamily / 28S ribosomal protein S26 / Mitochondrial ribosome subunit S26 / 28S ribosomal protein S27, mitochondrial / Ribosomal protein S23, mitochondrial / Ribosomal protein S23/S25, mitochondrial / Mitochondrial 28S ribosomal protein S31 / MRPS27/PTCD2 / Mitochondrial 28S ribosomal protein S27 / Mitochondrial ribosomal protein S23 / Mitochondrial 28S ribosomal protein S31 / Ribosomal protein S22, mitochondrial / 28S ribosomal protein S10, mitochondrial / : / Mitochondrial 28S ribosomal protein S22 / Ribosomal protein S29, mitochondrial / Ribosomal protein S28, mitochondrial / 28S ribosomal protein S18b, mitochondrial / Mitochondrial ribosomal protein MRP-S35 / 28S ribosomal protein S24, mitochondrial / Mitochondrial 28S ribosomal protein S34 / Pentatricopeptide repeat domain-containing protein 3 / 28S ribosomal protein S17, mitochondrial / : / : / Mitochondrial ribosome subunit S24 / Mitochondrial 28S ribosomal protein S34 / Small ribosomal subunit protein uS5m, N-terminal / Small ribosomal subunit protein mS39, PPR / : / 28S ribosomal protein S25, mitochondrial / Ribosomal protein L55, mitochondrial / Mitochondrial ribosomal protein L55 superfamily / : / Mitochondrial ribosomal protein L55 / Mitochondrial ribosomal protein L48 / 39S ribosomal protein L40, mitochondrial / Ribosomal protein S30, mitochondrial / Ribosomal protein L53, mitochondrial / 39S ribosomal protein L53/MRP-L53 / 39S ribosomal protein L42, mitochondrial / Mitochondrial 28S ribosomal protein S32 / Ribosomal protein L37, mitochondrial / Mitochondrial ribosomal protein L37 / Ribosomal protein 63, mitochondrial / Growth arrest/ DNA-damage-inducible protein-interacting protein 1 / Ribosomal protein L35, mitochondrial / Ribosomal protein L51, mitochondrial / Growth arrest and DNA-damage-inducible proteins-interacting protein 1 / Mitochondrial ribosomal subunit / Mitochondrial ribosome protein 63 / Ribosomal protein L37/S30 / Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily / : / : / Mitochondrial 28S ribosomal protein S30 (PDCD9) / 39S ribosomal protein L52, mitochondrial / Mitoribosomal protein mL52 / : / : / Large ribosomal subunit protein mL44, endonuclease domain / Ribosomal protein L28/L40, mitochondrial / Mitochondrial ribosomal protein L28 / Pentatricopeptide repeat domain / : / : / Large ribosomal subunit protein bL9m C-terminal domain / Large ribosomal subunit protein bL9m N-terminal domain / Tim44-like domain / Tim44-like domain / Tim44 / Ribosomal protein S27/S33, mitochondrial / : / Mitochondrial ribosomal subunit S27 / Ribosomal protein S24/S35, mitochondrial / : / Ribosomal protein L7/L12, oligomerisation / Ribosomal protein L7/L12, oligomerisation domain superfamily / Ribosomal protein L7/L12 dimerisation domain / Ribosomal protein L7/L12 / Ribosomal protein L7/L12, C-terminal / Ribosomal protein L7/L12 C-terminal domain / : / Ribosomal protein S24/S35, mitochondrial, conserved domain / Mitochondrial ribosomal subunit protein / Mitochondrial ribosomal protein L46 NUDIX / Ribosomal protein L50, mitochondria / MRPL44, double-stranded RNA binding domain / Ribosomal subunit 39S / MRPL44 dsRNA-binding domain / Ribosomal protein L46, N-terminal / 39S mitochondrial ribosomal protein L46 / Pentatricopeptide (PPR) repeat profile. / Ribosomal protein L49/IMG2 / Mitochondrial large subunit ribosomal protein (Img2)

Component:

Small ribosomal subunit protein uS12m / Small ribosomal subunit protein uS14m / Large ribosomal subunit protein bL33m / Large ribosomal subunit protein uL3m / Large ribosomal subunit protein bL19m / Small ribosomal subunit protein mS29 / Large ribosomal subunit protein bL12m / Small ribosomal subunit protein mS22 / Small ribosomal subunit protein mS25 / Small ribosomal subunit protein uS10m / Small ribosomal subunit protein mS35 / Small ribosomal subunit protein uS5m / Small ribosomal subunit protein uS11m / Small ribosomal subunit protein uS15m / Small ribosomal subunit protein bS21m / Small ribosomal subunit protein mS34 / Small ribosomal subunit protein bS6m / Small ribosomal subunit protein uS9m / Large ribosomal subunit protein bL28m / Large ribosomal subunit protein mL49 / Large ribosomal subunit protein mL62 / Mitochondrial inner membrane protein OXA1L / Large ribosomal subunit protein uL23m / Large ribosomal subunit protein mL51 / Large ribosomal subunit protein uL2m / Large ribosomal subunit protein mL54 / Large ribosomal subunit protein uL14m / Large ribosomal subunit protein bL21m / Large ribosomal subunit protein mL55 / Large ribosomal subunit protein uL10m / Large ribosomal subunit protein mL52 / Large ribosomal subunit protein mL41 / Large ribosomal subunit protein mL50 / Large ribosomal subunit protein mL43 / Large ribosomal subunit protein mL64 / Large ribosomal subunit protein uL30m / Small ribosomal subunit protein mS27 / Small ribosomal subunit protein mS31 / Large ribosomal subunit protein uL24m / Small ribosomal subunit protein mS37 / Large ribosomal subunit protein mL38 / Small ribosomal subunit protein uS3m / Large ribosomal subunit protein mL53 / Small ribosomal subunit protein mS39 / Large ribosomal subunit protein mL48 / Large ribosomal subunit protein bL34m / Large ribosomal subunit protein mL63 / Large ribosomal subunit protein mL45 / Large ribosomal subunit protein bL32m / Large ribosomal subunit protein bL20m / Large ribosomal subunit protein uL13m / Large ribosomal subunit protein bL9m / Large ribosomal subunit protein uL4m / Large ribosomal subunit protein uL1m / Small ribosomal subunit protein mS26 / Large ribosomal subunit protein mL37 / Large ribosomal subunit protein uL18m / Large ribosomal subunit protein mL46 / Large ribosomal subunit protein mL44 / Large ribosomal subunit protein uL29m / Large ribosomal subunit protein mL65 / Large ribosomal subunit protein mL40 / Large ribosomal subunit protein bL17m / Large ribosomal subunit protein mL66 / Small ribosomal subunit protein bS22, mitochondrial / Large ribosomal subunit protein uL22m / Large ribosomal subunit protein uL16m / Large ribosomal subunit protein mL39 / Large ribosomal subunit protein bL35m / Large ribosomal subunit protein uL15m / Large ribosomal subunit protein bL36m / Large ribosomal subunit protein bL27m / Small ribosomal subunit protein mS33 / Small ribosomal subunit protein bS1m / Small ribosomal subunit protein uS17m / Small ribosomal subunit protein uS7m / Small ribosomal subunit protein uS2m / Large ribosomal subunit protein uL11m / Small ribosomal subunit protein bS16m / Small ribosomal subunit protein bS18m / Small ribosomal subunit protein mS23 / Small ribosomal subunit protein mS40 / Large ribosomal subunit protein mL42

• Biological species: Homo sapiens (human)
• Method: single particle reconstruction / cryo EM / Resolution: 3.6 Å
• Authors: Schoendorf T / Petrychenko V / Kotan I / Cruz-Zaragoza LD / Dahal D / Wang C / Gal T / Dennerlein S / Kramer G / Fischer N / Rehling P

Funding support

European Union, Germany, 4 items

Organization	Grant number	Country
European Research Council (ERC)	ERCAdG No. 101095062	European Union
German Research Foundation (DFG)	SFB1565	Germany
Max Planck Society		Germany
Germanys Excellence Strategy	390729940	Germany

• Citation: Journal: Nat Struct Mol Biol / Year: 2026; Title: Membrane insertion of mitochondrial-encoded proteins regulates ribosome decoding speed.; Authors: Thomas Schöndorf / Valentyn Petrychenko / Ilgin Kotan / Drishan Dahal / Natalia Napieraj / Luis Daniel Cruz-Zaragoza / Cong Wang / Oliver Urbach / Tanja Gall / Sven Dennerlein / Günter Kramer / Niels Fischer / Peter Rehling / ; Abstract: The human mitochondrial genome encodes 13 subunits of the oxidative phosphorylation system essential for energy metabolism to drive cellular activities. Translation of 11 mRNAs by membrane-bound ribosomes is coupled to insertion of the nascent polypeptides into the inner membrane aided by the OXA1L insertase. To this end, the mechanism of membrane insertion of nascent polypeptides and the functional link to the translation process are not sufficiently understood. Here, we applied ribosome profiling to assess translation dynamics in combination with cryo-electron microscopy analysis of a COX1 ribosome-nascent chain complex to visualize cotranslational folding of the nascent chain. We find that the membrane topology of the translation product impacts translation speed and that positioning of amphipathic helices in the ribosome vestibule induces structural changes, correlating with translation pausing events. Thus, our findings reveal a link between translation process and folding and membrane insertion of nascent polypeptides at the inner mitochondrial membrane.

History

Deposition	Aug 4, 2025	-
Header (metadata) release	Aug 12, 2026	-
Map release	Aug 12, 2026	-
Update	Aug 12, 2026	-
Current status	Aug 12, 2026	Processing site: PDBe / Status: Released

Map

• File: Download / File: emd_54639.map.gz / Format: CCP4 / Size: 244.1 MB / Type: IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)
• Voxel size: X=Y=Z: 1.16 Å

Density

Contour Level	By AUTHOR: 0.7
Minimum - Maximum	-0.80207086 - 2.6916938
Average (Standard dev.)	0.002646609 (±0.15601093)

• Symmetry: Space group: 1

Details

EMDB XML:

Map geometry	Axis order X Y Z Origin 0 0 0 Dimensions 400 400 400 Spacing 400 400 400
Cell	A=B=C: 464.0 Å α=β=γ: 90.0 °

Supplemental data

Mask #1

• File: emd_54639_msk_1.map

Half map: #2

• File: emd_54639_half_map_1.map

Half map: #1

• File: emd_54639_half_map_2.map

Sample components

Entire : Human mitochondrial 55S ribosome complex with tRNAs and COX1 nasc...

• Entire: Name: Human mitochondrial 55S ribosome complex with tRNAs and COX1 nascent chain

Components

• Complex: Human mitochondrial 55S ribosome complex with tRNAs and COX1 nascent chain
  • RNA: 16S mitochondrial rRNA
  • RNA: mitochondrial tRNAVal
  • Protein or peptide: Large ribosomal subunit protein uL2m
  • Protein or peptide: Large ribosomal subunit protein uL3m
  • Protein or peptide: Large ribosomal subunit protein uL4m
  • Protein or peptide: Large ribosomal subunit protein bL9m
  • Protein or peptide: Large ribosomal subunit protein uL10m
  • Protein or peptide: Large ribosomal subunit protein uL11m
  • Protein or peptide: Large ribosomal subunit protein uL14m
  • Protein or peptide: Large ribosomal subunit protein uL15m
  • Protein or peptide: Large ribosomal subunit protein uL16m
  • Protein or peptide: Large ribosomal subunit protein bL17m
  • Protein or peptide: Large ribosomal subunit protein uL18m
  • Protein or peptide: Large ribosomal subunit protein bL19m
  • Protein or peptide: Large ribosomal subunit protein bL20m
  • Protein or peptide: Large ribosomal subunit protein bL21m
  • Protein or peptide: Large ribosomal subunit protein uL22m
  • Protein or peptide: Large ribosomal subunit protein bL27m
  • Protein or peptide: Large ribosomal subunit protein bL28m
  • Protein or peptide: Large ribosomal subunit protein uL29m
  • Protein or peptide: Large ribosomal subunit protein uL30m
  • Protein or peptide: Large ribosomal subunit protein bL32m
  • Protein or peptide: Large ribosomal subunit protein bL33m
  • Protein or peptide: Large ribosomal subunit protein bL34m
  • Protein or peptide: Large ribosomal subunit protein bL35m
  • Protein or peptide: Large ribosomal subunit protein bL36m
  • Protein or peptide: Large ribosomal subunit protein uL1m
  • Protein or peptide: Large ribosomal subunit protein bL12m
  • Protein or peptide: Large ribosomal subunit protein mL37
  • Protein or peptide: Large ribosomal subunit protein mL38
  • Protein or peptide: Large ribosomal subunit protein mL39
  • Protein or peptide: Large ribosomal subunit protein mL40
  • Protein or peptide: Large ribosomal subunit protein mL41
  • Protein or peptide: Large ribosomal subunit protein mL42
  • Protein or peptide: Large ribosomal subunit protein mL43
  • Protein or peptide: Large ribosomal subunit protein mL44
  • Protein or peptide: Large ribosomal subunit protein mL46
  • Protein or peptide: Large ribosomal subunit protein mL48
  • Protein or peptide: Large ribosomal subunit protein mL49
  • Protein or peptide: Large ribosomal subunit protein mL50
  • Protein or peptide: Large ribosomal subunit protein mL51
  • Protein or peptide: Large ribosomal subunit protein mL52
  • Protein or peptide: Large ribosomal subunit protein mL54
  • Protein or peptide: Large ribosomal subunit protein mL55
  • Protein or peptide: Large ribosomal subunit protein mL63
  • Protein or peptide: Large ribosomal subunit protein mL62
  • Protein or peptide: Large ribosomal subunit protein mL64
  • Protein or peptide: Large ribosomal subunit protein mL66
  • Protein or peptide: Large ribosomal subunit protein mL65
  • RNA: 12S mitochondrial rRNA
  • Protein or peptide: Small ribosomal subunit protein uS2m
  • Protein or peptide: Small ribosomal subunit protein uS3m
  • Protein or peptide: Small ribosomal subunit protein uS5m
  • Protein or peptide: Small ribosomal subunit protein bS6m
  • Protein or peptide: Small ribosomal subunit protein uS7m
  • Protein or peptide: Small ribosomal subunit protein uS9m
  • Protein or peptide: Small ribosomal subunit protein uS10m
  • Protein or peptide: Small ribosomal subunit protein uS11m
  • Protein or peptide: Small ribosomal subunit protein uS12m
  • Protein or peptide: Small ribosomal subunit protein uS14m
  • Protein or peptide: Small ribosomal subunit protein uS15m
  • Protein or peptide: Small ribosomal subunit protein bS16m
  • Protein or peptide: Small ribosomal subunit protein uS17m
  • Protein or peptide: Small ribosomal subunit protein mS40
  • Protein or peptide: Small ribosomal subunit protein bS18m
  • Protein or peptide: Small ribosomal subunit protein mS22
  • Protein or peptide: Small ribosomal subunit protein mS23
  • Protein or peptide: Small ribosomal subunit protein mS25
  • Protein or peptide: Small ribosomal subunit protein mS26
  • Protein or peptide: Small ribosomal subunit protein mS27
  • Protein or peptide: Small ribosomal subunit protein bS1m
  • Protein or peptide: Small ribosomal subunit protein mS29
  • Protein or peptide: Small ribosomal subunit protein mS31
  • Protein or peptide: Small ribosomal subunit protein mS33
  • Protein or peptide: Small ribosomal subunit protein mS34
  • Protein or peptide: Small ribosomal subunit protein mS35
  • Protein or peptide: Small ribosomal subunit protein bS22, mitochondrial
  • Protein or peptide: Small ribosomal subunit protein mS39
  • RNA: mRNA (Visualization example)
  • RNA: A-site tRNA (Visualisation example)
  • RNA: P-site tRNA (Visualisation example)
  • Protein or peptide: COX1 nascent chain
  • Protein or peptide: Large ribosomal subunit protein uL24m
  • Protein or peptide: Large ribosomal subunit protein mL45
  • Protein or peptide: Mitochondrial inner membrane protein OXA1L
• Protein or peptide: Large ribosomal subunit protein uL13m
• Protein or peptide: Large ribosomal subunit protein uL23m
• Protein or peptide: Large ribosomal subunit protein mL53
• Protein or peptide: Small ribosomal subunit protein bS21m
• Protein or peptide: Small ribosomal subunit protein mS37
• Ligand: POTASSIUM ION
• Ligand: MAGNESIUM ION
• Ligand: VALINE
• Ligand: FE2/S2 (INORGANIC) CLUSTER
• Ligand: NICOTINAMIDE-ADENINE-DINUCLEOTIDE
• Ligand: ZINC ION
• Ligand: ADENOSINE-5'-TRIPHOSPHATE
• Ligand: GUANOSINE-5'-DIPHOSPHATE

Supramolecule #1: Human mitochondrial 55S ribosome complex with tRNAs and COX1 nasc...

• Supramolecule: Name: Human mitochondrial 55S ribosome complex with tRNAs and COX1 nascent chain; type: complex / ID: 1 / Parent: 0 ; Macromolecule list: #1-#8, #10-#18, #21-#24, #28-#48, #50-#56, #25-#27, #57-#69, #71-#81, #83-#88, #20, #89-#90
• Source (natural): Organism: Homo sapiens (human)

Macromolecule #1: 16S mitochondrial rRNA

• Macromolecule: Name: 16S mitochondrial rRNA / type: rna / ID: 1 / Number of copies: 1
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 500.727125 KDa

Sequence

String:

GCUAAACCUA GCCCCAAACC CACUCCACCU UACUACCAGA CAACCUUAGC CAAACCAUUU ACCCAAAUAA AGUAUAGGCG AUAGAAAUU GAAACCUGGC GCAAUAGAUA UAGUACCGCA AGGGAAAGAU GAAAAAUUAU AACCAAGCAU AAUAUAGCAA G GACUAACC CCUAUACCUU CUGCAUAAUG AAUUAACUAG AAAUAACUUU GCAAGGAGAG CCAAAGCUAA GACCCCCGAA AC CAGACGA GCUACCUAAG AACAGCUAAA AGAGCACACC CGUCUAUGUA GCAAAAUAGU GGGAAGAUUU AUAGGUAGAG GCG ACAAAC CUACCGAGCC UGGUGAUAGC UGGUUGUCCA AGAUAGAAUC UUAGUUCAAC UUUAAAUUUG CCCACAGAAC CCUC UAAAU CCCCUUGUAA AUUUAACUGU UAGUCCAAAG AGGAACAGCU CUUUGGACAC UAGGAAAAAA CCUUGUAGAG AGAGU AAAA AAUUUAACAC CCAUAGUAGG CCUAAAAGCA GCCACCAAUU AAGAAAGCGU UCAAGCUCAA CACCCACUAC CUAAAA AAU CCCAAACAUA UAACUGAACU CCUCACACCC AAUUGGACCA AUCUAUCACC CUAUAGAAGA ACUAAUGUUA GUAUAAG UA ACAUGAAAAC AUUCUCCUCC GCAUAAGCCU GCGUCAGAUU AAAACACUGA ACUGACAAUU AACAGCCCAA UAUCUACA A UCAACCAACA AGUCAUUAUU ACCCUCACUG UCAACCCAAC ACAGGCAUGC UCAUAAGGAA AGGUUAAAAA AAGUAAAAG GAACUCGGCA AAUCUUACCC CGCCUGUUUA CCAAAAACAU CACCUCUAGC AUCACCAGUA UUAGAGGCAC CGCCUGCCCA GUGACACAU GUUUAACGGC CGCGGUACCC UAACCGUGCA AAGGUAGCAU AAUCACUUGU UCCUUAA(1MA)UA GGGACCU GU AUGAAUGGCU CCACGAGGGU UCAGCUGUCU CUUACUUUUA ACCAGUGAAA UUGACCUGCC CGUGAAGAGG CGGGCAUA A CACAGCAAGA CGAGAAGACC CUAUGGAGCU UUAAUUUAUU AAUGCAAACA GUACCUAACA AACCCACAGG UCCUAAACU ACCAAACCUG CAUUAAAAAU UUCGGUUG(OMG)G GCGACCUCGG AGCAGAACCC AACCUCCGAG CAGUACAUGC UAAGAC UUC ACCAGUCAAA GCGAACUACU AUACUCAAUU GAUCCAAUAA CUUGACCAAC GGAACAAGUU ACCCUAGGGA UAACAGC GC AAUCCUAUUC UAGAGUCCAU AUCAACAAUA GGGUUUACGA CCUCGAUGUU GGAUCAGGAC AUCCCGAUGG UGCAGCCG C UAUUAAAGGU UCGUU(OMU)(OMG)UUC AACGAUUAAA GUCCUACGUG AUC(PSU)GAGUUC AGACCGGAGU AAUCCAG GU CGGUUUCUAU CUACUUUCAA AUUCCUCCCU GUACGAAAGG ACAAGAGAAA UAAGGCCUAC UUCACAAAGC GCCUUCCC C CGUAAAUGAU AUCAUCUCAA CUUAGUAUUA UACCCACACC CACCCAAGAA CAGGGUUUGU

GENBANK: GENBANK: MK321331.1

Macromolecule #2: mitochondrial tRNAVal

• Macromolecule: Name: mitochondrial tRNAVal / type: rna / ID: 2 / Number of copies: 1
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 22.989752 KDa

Sequence

String:

CAGAGUGU(1MA)(2MG) CUUAACACAA AGCACCCAAC UUACAC(PSU)UAG GAGAUUUCAA CUUAACUUGA CCGCUCUG A CCA

GENBANK: GENBANK: NC_012920.1

Macromolecule #25: 12S mitochondrial rRNA

• Macromolecule: Name: 12S mitochondrial rRNA / type: rna / ID: 25 / Number of copies: 1
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 306.218312 KDa

Sequence

String:

AUAGGUUUGG UCCUAGCCUU UCUAUUAGCU CUUAGUAAGA UUACACAUGC AAGCAUCCCC GUUCCAGUGA GUUCACCCUC UAAAUCACC ACGAUCAAAA GGGACAAGCA UCAAGCACGC AGCAAUGCAG CUCAAAACGC UUAGCCUAGC CACACCCCCA C GGGAAACA GCAGUGAUUA ACCUUUAGCA AUAAACGAAA GUUUAACUAA GCUAUACUAA CCCCAGGGUU GGUCAAUUUC GU GCCAGCC ACCGCGGUCA CACGAUUAAC CCAAGUCAAU AGAAGCCGGC GUAAAGAGUG UUUUAGAUCA CCCCCUCCCC AAU AAAGCU AAAACUCACC UGAGUUGUAA AAAACUCCAG UUGACACAAA AUAGACUACG AAAGUGGCUU UAACAUAUCU GAAC ACACA AUAGCUAAGA CCCAAACUGG GA(5MU)UAGAUAC CCCACUAUGC UUAGCCCUAA ACCUCAACAG UUAAAUCAAC A AAACUGCU CGCCAGAACA CUACGAGCCA CAGCUUAAAA CUCAAAGGAC CUGGCGGUGC UUCAUAUCCC UCUAGAGGAG CC UGUUCUG UAAUCGAUAA ACCCCGAUCA ACCUCACCAC CUCUUGCUCA GCCUAUAUAC CGCCAUCUUC AGCAAACCCU GAU GAAGGC UACAAAGUAA GCGCAAGUAC CCACGUAAAG ACGUUAGGUC AAGGUGUAGC CCAUGAGGUG GCAAGAAAUG GGCU ACAUU UUCUACCCCA GAAAACUACG AUAGCCCUUA UGAAACUUAA GGGUCGAAGG UGGAUUUAGC AGUAAACUGA GAGUA GAGU GCUUAGUUGA ACAGGGCCCU GAAGCGCGUA CACACCG(B8T)C(5MC) GUCACCCUCC UCAAGUAUAC UUCAAAGG A CAUUUAACUA AAACCCCUAC GCAUUUAUAU AGAGGAGACA AGUCGUAACA UGGUAAGUGU ACUGG(MA6)(MA6)AGU G CACUUGGA CGAACC

GENBANK: GENBANK: MN849737.1

Macromolecule #85: mRNA (Visualization example)

• Macromolecule: Name: mRNA (Visualization example) / type: rna / ID: 85 / Number of copies: 1
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 10.54329 KDa

Sequence

String:

UUAAAUGGUA GUUUAUAAAA AAAUUUACUU AAA

Macromolecule #86: A-site tRNA (Visualisation example)

• Macromolecule: Name: A-site tRNA (Visualisation example) / type: rna / ID: 86 / Number of copies: 1
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 21.642854 KDa

Sequence

String:

UGGUAUAUAG UUUAAACAAA ACGAAUGAUU UACACUCAUU CAAUUAUGAU AAUCAUAUUU ACCAACCA

GENBANK: GENBANK: LC530722.1

Macromolecule #87: P-site tRNA (Visualisation example)

• Macromolecule: Name: P-site tRNA (Visualisation example) / type: rna / ID: 87 / Number of copies: 1
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 22.626441 KDa

Sequence

String:

UAGGGAAUAG UUUAACAAAA CUCCUGACUC AUCCUCAGGA GAUGGAGGUU CAAUUCCUCC UUCCCUAACC A

Macromolecule #3: Large ribosomal subunit protein uL2m

• Macromolecule: Name: Large ribosomal subunit protein uL2m / type: protein_or_peptide / ID: 3 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 33.355941 KDa

Sequence

String:

MALCALTRAL RSLNLAPPTV AAPAPSLFPA AQMMNNGLLQ QPSALMLLPC RPVLTSVALN ANFVSWKSRT KYTITPVKMR KSGGRDHTG RIRVHGIGGG HKQRYRMIDF LRFRPEETKS GPFEEKVIQV RYDPCRSADI ALVAGGSRKR WIIATENMQA G DTILNSNH IGRMAVAARE GDAHPLGALP VGTLINNVES EPGRGAQYIR AAGTCGVLLR KVNGTAIIQL PSKRQMQVLE TC VATVGRV SNVDHNKRVI GKAGRNRWLG KRPNSGRWHR KGGWAGRKIR PLPPMKSYVK LPSASAQS

UniProtKB: Large ribosomal subunit protein uL2m

Macromolecule #4: Large ribosomal subunit protein uL3m

• Macromolecule: Name: Large ribosomal subunit protein uL3m / type: protein_or_peptide / ID: 4 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 38.689562 KDa

Sequence

String:

MPGWRLLTQV GAQVLGRLGD GLGAALGPGN RTHIWLFVRG LHGKSGTWWD EHLSEENVPF IKQLVSDEDK AQLASKLCPL KDEPWPIHP WEPGSFRVGL IALKLGMMPL WTKDGQKHVV TLLQVQDCHV LKYTSKENCN GKMATLSVGG KTVSRFRKAT S ILEFYREL GLPPKQTVKI FNITDNAAIK PGTPLYAAHF RPGQYVDVTA KTIGKGFQGV MKRWGFKGQP ATHGQTKTHR RP GAVATGD IGRVWPGTKM PGKMGNIYRT EYGLKVWRIN TKHNIIYVNG SVPGHKNCLV KVKDSKLPAY KDLGKNLPFP TYF PDGDEE ELPEDLYDEN VCQPGAPSIT FA

UniProtKB: Large ribosomal subunit protein uL3m

Macromolecule #5: Large ribosomal subunit protein uL4m

• Macromolecule: Name: Large ribosomal subunit protein uL4m / type: protein_or_peptide / ID: 5 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 34.970195 KDa

Sequence

String:

MLQFVRAGAR AWLRPTGSQG LSSLAEEAAR ATENPEQVAS EGLPEPVLRK VELPVPTHRR PVQAWVESLR GFEQERVGLA DLHPDVFAT APRLDILHQV AMWQKNFKRI SYAKTKTRAE VRGGGRKPWP QKGTGRARHG SIRSPLWRGG GVAHGPRGPT S YYYMLPMK VRALGLKVAL TVKLAQDDLH IMDSLELPTG DPQYLTELAH YRRWGDSVLL VDLTHEEMPQ SIVEATSRLK TF NLIPAVG LNVHSMLKHQ TLVLTLPTVA FLEDKLLWQD SRYRPLYPFS LPYSDFPRPL PHATQGPAAT PYHC

UniProtKB: Large ribosomal subunit protein uL4m

Macromolecule #6: Large ribosomal subunit protein bL9m

• Macromolecule: Name: Large ribosomal subunit protein bL9m / type: protein_or_peptide / ID: 6 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 30.296355 KDa

Sequence

String:

MAAPVVTAPG RALLRAGAGR LLRGGVQELL RPRHEGNAPD LACNFSLSQN RGTVIVERWW KVPLAGEGRK PRLHRRHRVY KLVEDTKHR PKENLELILT QSVENVGVRG DLVSVKKSLG RNRLLPQGLA VYASPENKKL FEEEKLLRQE GKLEKIQTKA G EATVKFLK SCRLEVGMKN NVKWELNPEI VARHFFKNLG VVVAPHTLKL PEEPITRWGE YWCEVTVNGL DTVRVPMSVV NF EKPKTKR YKYWLAQQAA KAMAPTSPQI

UniProtKB: Large ribosomal subunit protein bL9m

Macromolecule #7: Large ribosomal subunit protein uL10m

• Macromolecule: Name: Large ribosomal subunit protein uL10m / type: protein_or_peptide / ID: 7 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 29.322529 KDa

Sequence

String:

MAAAVAGMLR GGLLPQAGRL PTLQTVRYGS KAVTRHRRVM HFQRQKLMAV TEYIPPKPAI HPSCLPSPPS PPQEEIGLIR LLRREIAAV FQDNRMIAVC QNVALSAEDK LLMRHQLRKH KILMKVFPNQ VLKPFLEDSK YQNLLPLFVG HNMLLVSEEP K VKEMVRIL RTVPFLPLLG GCIDDTILSR QGFINYSKLP SLPLVQGELV GGLTCLTAQT HSLLQHQPLQ LTTLLDQYIR EQ REKDSVM SANGKPDPDT VPDS

UniProtKB: Large ribosomal subunit protein uL10m

Macromolecule #8: Large ribosomal subunit protein uL11m

• Macromolecule: Name: Large ribosomal subunit protein uL11m / type: protein_or_peptide / ID: 8 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 20.716227 KDa

Sequence

String:

MSKLGRAARG LRKPEVGGVI RAIVRAGLAM PGPPLGPVLG QRGVSINQFC KEFNERTKDI KEGIPLPTKI LVKPDRTFEI KIGQPTVSY FLKAAAGIEK GARQTGKEVA GLVTLKHVYE IARIKAQDEA FALQDVPLSS VVRSIIGSAR SLGIRVVKDL S SEELAAFQ KERAIFLAAQ KEADLAAQEE AAKK

UniProtKB: Large ribosomal subunit protein uL11m

Macromolecule #9: Large ribosomal subunit protein uL13m

• Macromolecule: Name: Large ribosomal subunit protein uL13m / type: protein_or_peptide / ID: 9 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 20.617828 KDa

Sequence

String:

(ACE)SSFSRAPQQ WATFARIWYL LDGKMQPPGK LAAMASIRLQ GLHKPVYHAL SDCGDHVVIM NTRHIAFSGN KWEQKV YSS HTGYPGGFRQ VTAAQLHLRD PVAIVKLAIY GMLPKNLHRR TMMERLHLFP DEYIPEDILK NLVEELPQPR KIPKRLD EY TQEEIDAFPR LWTPPEDYRL

UniProtKB: Large ribosomal subunit protein uL13m

Macromolecule #10: Large ribosomal subunit protein uL14m

• Macromolecule: Name: Large ribosomal subunit protein uL14m / type: protein_or_peptide / ID: 10 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 15.973702 KDa

Sequence

String:

MAFFTGLWGP FTCVSRVLSH HCFSTTGSLS AIQKMTRVRV VDNSALGNSP YHRAPRCIHV YKKNGVGKVG DQILLAIKGQ KKKALIVGH CMPGPRMTPR FDSNNVVLIE DNGNPVGTRI KTPIPTSLRK REGEYSKVLA IAQNFV

UniProtKB: Large ribosomal subunit protein uL14m

Macromolecule #11: Large ribosomal subunit protein uL15m

• Macromolecule: Name: Large ribosomal subunit protein uL15m / type: protein_or_peptide / ID: 11 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 33.47382 KDa

Sequence

String:

MAGPLQGGGA RALDLLRGLP RVSLANLKPN PGSKKPERRP RGRRRGRKCG RGHKGERQRG TRPRLGFEGG QTPFYIRIPK YGFNEGHSF RRQYKPLSLN RLQYLIDLGR VDPSQPIDLT QLVNGRGVTI QPLKRDYGVQ LVEEGADTFT AKVNIEVQLA S ELAIAAIE KNGGVVTTAF YDPRSLDIVC KPVPFFLRGQ PIPKRMLPPE ELVPYYTDAK NRGYLADPAK FPEARLELAR KY GYILPDI TKDELFKMLC TRKDPRQIFF GLAPGWVVNM ADKKILKPTD ENLLKYYTS

UniProtKB: Large ribosomal subunit protein uL15m

Macromolecule #12: Large ribosomal subunit protein uL16m

• Macromolecule: Name: Large ribosomal subunit protein uL16m / type: protein_or_peptide / ID: 12 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 28.496285 KDa

Sequence

String:

MWRLLARASA PLLRVPLSDS WALLPASAGV KTLLPVPSFE DVSIPEKPKL RFIERAPLVP KVRREPKNLS DIRGPSTEAT EFTEGNFAI LALGGGYLHW GHFEMMRLTI NRSMDPKNMF AIWRVPAPFK PITRKSVGHR MGGGKGAIDH YVTPVKAGRL V VEMGGRCE FEEVQGFLDQ VAHKLPFAAK AVSRGTLEKM RKDQEERERN NQNPWTFERI ATANMLGIRK VLSPYDLTHK GK YWGKFYM PKRV

UniProtKB: Large ribosomal subunit protein uL16m

Macromolecule #13: Large ribosomal subunit protein bL17m

• Macromolecule: Name: Large ribosomal subunit protein bL17m / type: protein_or_peptide / ID: 13 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 20.083266 KDa

Sequence

String:

MRLSVAAAIS HGRVFRRMGL GPESRIHLLR NLLTGLVRHE RIEAPWARVD EMRGYAEKLI DYGKLGDTNE RAMRMADFWL TEKDLIPKL FQVLAPRYKD QTGGYTRMLQ IPNRSLDRAK MAVIEYKGNC LPPLPLPRRD SHLTLLNQLL QGLRQDLRQS Q EASNHSSH TAQTPGI

UniProtKB: Large ribosomal subunit protein bL17m

Macromolecule #14: Large ribosomal subunit protein uL18m

• Macromolecule: Name: Large ribosomal subunit protein uL18m / type: protein_or_peptide / ID: 14 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 20.60757 KDa

Sequence

String:

MALRSRFWGL FSVCRNPGCR FAALSTSSEP AAKPEVDPVE NEAVAPEFTN RNPRNLELLS VARKERGWRT VFPSREFWHR LRVIRTQHH VEALVEHQNG KVVVSASTRE WAIKKHLYST RNVVACESIG RVLAQRCLEA GINFMVYQPT PWEAASDSMK R LQSAMTEG GVVLREPQRI YE

UniProtKB: Large ribosomal subunit protein uL18m

Macromolecule #15: Large ribosomal subunit protein bL19m

• Macromolecule: Name: Large ribosomal subunit protein bL19m / type: protein_or_peptide / ID: 15 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 33.584996 KDa

Sequence

String:

MAACIAAGHW AAMGLGRSFQ AARTLLPPPA SIACRVHAGP VRQQSTGPSE PGAFQPPPKP VIVDKHRPVE PERRFLSPEF IPRRGRTDP LKFQIERKDM LERRKVLHIP EFYVGSILRV TTADPYASGK ISQFLGICIQ RSGRGLGATF ILRNVIEGQG V EICFELYN PRVQEIQVVK LEKRLDDSLL YLRDALPEYS TFDVNMKPVV QEPNQKVPVN ELKVKMKPKP WSKRWERPNF NI KGIRFDL CLTEQQMKEA QKWNQPWLEF DMMREYDTSK IEAAIWKEIE ASKRS

UniProtKB: Large ribosomal subunit protein bL19m

Macromolecule #16: Large ribosomal subunit protein bL20m

• Macromolecule: Name: Large ribosomal subunit protein bL20m / type: protein_or_peptide / ID: 16 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 17.479654 KDa

Sequence

String:

MVFLTAQLWL RNRVTDRYFR IQEVLKHARH FRGRKNRCYR LAVRTVIRAF VKCTKARYLK KKNMRTLWIN RITAASQEHG LKYPALIGN LVKCQVELNR KVLADLAIYE PKTFKSLAAL ASRRRHEGFA AALGDGKEPE GIFSRVVQYH

UniProtKB: Large ribosomal subunit protein bL20m

Macromolecule #17: Large ribosomal subunit protein bL21m

• Macromolecule: Name: Large ribosomal subunit protein bL21m / type: protein_or_peptide / ID: 17 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 22.847682 KDa

Sequence

String:

MAASSLTVTL GRLASACSHS ILRPSGPGAA SLWSASRRFN SQSTSYLPGY VPKTSLSSPP WPEVVLPDPV EETRHHAEVV KKVNEMIVT GQYGRLFAVV HFASRQWKVT SEDLILIGNE LDLACGERIR LEKVLLVGAD NFTLLGKPLL GKDLVRVEAT V IEKTESWP RIIMRFRKRK NFKKKRIVTT PQTVLRINSI EIAPCLL

UniProtKB: Large ribosomal subunit protein bL21m

Macromolecule #18: Large ribosomal subunit protein uL22m

• Macromolecule: Name: Large ribosomal subunit protein uL22m / type: protein_or_peptide / ID: 18 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 23.683732 KDa

Sequence

String:

MAAAVLGQLG ALWIHNLRSR GKLALGVLPQ SYIHTSASLD ISRKWEKKNK IVYPPQLPGE PRRPAEIYHC RRQIKYSKDK MWYLAKLIR GMSIDQALAQ LEFNDKKGAK IIKEVLLEAQ DMAVRDHNVE FRSNLYIAES TSGRGQCLKR IRYHGRGRFG I MEKVYCHY FVKLVEGPPP PPEPPKTAVA HAKEYIQQLR SRTIVHTL

UniProtKB: Large ribosomal subunit protein uL22m

Macromolecule #19: Large ribosomal subunit protein uL23m

• Macromolecule: Name: Large ribosomal subunit protein uL23m / type: protein_or_peptide / ID: 19 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 17.702029 KDa

Sequence

String:

(ACE)ARNVVYPLY RLGGPQLRVF RTNFFIQLVR PGVAQPEDTV QFRIPMEMTR VDLRNYLEGI YNVPVAAVRT RVQHGS NKR RDHRNVRIKK PDYKVAYVQL AHGQTFTFPD LFPEKDESPE GSAADDLYSM LEEERQQRQS SDPRRGGVPS WFGL

UniProtKB: Large ribosomal subunit protein uL23m

Macromolecule #20: Large ribosomal subunit protein uL24m

• Macromolecule: Name: Large ribosomal subunit protein uL24m / type: protein_or_peptide / ID: 20 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 24.953875 KDa

Sequence

String:

MRLSALLALA SKVTLPPHYR YGMSPPGSVA DKRKNPPWIR RRPVVVEPIS DEDWYLFCGD TVEILEGKDA GKQGKVVQVI RQRNWVVVG GLNTHYRYIG KTMDYRGTMI PSEAPLLHRQ VKLVDPMDRK PTEIEWRFTE AGERVRVSTR SGRIIPKPEF P RADGIVPE TWIDGPKDTS VEDALERTYV PCLKTLQEEV MEAMGIKETR KYKKVYWY

UniProtKB: Large ribosomal subunit protein uL24m

Macromolecule #21: Large ribosomal subunit protein bL27m

• Macromolecule: Name: Large ribosomal subunit protein bL27m / type: protein_or_peptide / ID: 21 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 16.102859 KDa

Sequence

String:

MASVVLALRT RTAVTSLLSP TPATALAVRY ASKKSGGSSK NLGGKSSGRR QGIKKMEGHY VHAGNIIATQ RHFRWHPGAH VGVGKNKCL YALEEGIVRY TKEVYVPHPR NTEAVDLITR LPKGAVLYKT FVHVVPAKPE GTFKLVAML

UniProtKB: Large ribosomal subunit protein bL27m

Macromolecule #22: Large ribosomal subunit protein bL28m

• Macromolecule: Name: Large ribosomal subunit protein bL28m / type: protein_or_peptide / ID: 22 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 30.202867 KDa

Sequence

String:

MPLHKYPVWL WKRLQLREGI CSRLPGHYLR SLEEERTPTP VHYRPHGAKF KINPKNGQRE RVEDVPIPIY FPPESQRGLW GGEGWILGQ IYANNDKLSK RLKKVWKPQL FEREFYSEIL DKKFTVTVTM RTLDLIDEAY GLDFYILKTP KEDLCSKFGM D LKRGMLLR LARQDPQLHP EDPERRAAIY DKYKEFAIPE EEAEWVGLTL EEAIEKQRLL EEKDPVPLFK IYVAELIQQL QQ QALSEPA VVQKRASGQ

UniProtKB: Large ribosomal subunit protein bL28m

Macromolecule #23: Large ribosomal subunit protein uL29m

• Macromolecule: Name: Large ribosomal subunit protein uL29m / type: protein_or_peptide / ID: 23 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 29.508535 KDa

Sequence

String:

MAAAGLALLC RRVSSALKSS RSLITPQVPA CTGFFLSLLP KSTPNVTSFH QYRLLHTTLS RKGLEEFFDD PKNWGQEKVK SGAAWTCQQ LRNKSNEDLH KLWYVLLKER NMLLTLEQEA KRQRLPMPSP ERLDKVVDSM DALDKVVQER EDALRLLQTG Q ERARPGAW RRDIFGRIIW HKFKQWVIPW HLNKRYNRKR FFALPYVDHF LRLEREKRAR IKARKENLER KKAKILLKKF PH LAEAQKS SLV

UniProtKB: Large ribosomal subunit protein uL29m

Macromolecule #24: Large ribosomal subunit protein uL30m

• Macromolecule: Name: Large ribosomal subunit protein uL30m / type: protein_or_peptide / ID: 24 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 18.582812 KDa

Sequence

String:

MAGILRLVVQ WPPGRLQTVT KGVESLICTD WIRHKFTRSR IPEKVFQASP EDHEKYGGDP QNPHKLHIVT RIKSTRRRPY WEKDIIKML GLEKAHTPQV HKNIPSVNAK LKVVKHLIRI KPLKLPQGLP AEENMSNTCL KSTGELVVQW HLKPVEQKAH E S

UniProtKB: Large ribosomal subunit protein uL30m

Macromolecule #26: Small ribosomal subunit protein uS2m

• Macromolecule: Name: Small ribosomal subunit protein uS2m / type: protein_or_peptide / ID: 26 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 33.298238 KDa

Sequence

String:

MATSSAALPR ILGAGARAPS RWLGFLGKAT PRPARPSRRT LGSATALMIR ESEDSTDFND KILNEPLKHS DFFNVKELFS VRSLFDARV HLGHKAGCRH RFMEPYIFGS RLDHDIIDLE QTATHLQLAL NFTAHMAYRK GIILFISRNR QFSYLIENMA R DCGEYAHT RYFRGGMLTN ARLLFGPTVR LPDLIIFLHT LNNIFEPHVA VRDAAKMNIP TVGIVDTNCN PCLITYPVPG ND DSPLAVH LYCRLFQTAI TRAKEKRQQV EALYRLQGQK EPGDQGPAHP PGADMSHSL

UniProtKB: Small ribosomal subunit protein uS2m

Macromolecule #27: Small ribosomal subunit protein uS3m

• Macromolecule: Name: Small ribosomal subunit protein uS3m / type: protein_or_peptide / ID: 27 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 19.046164 KDa

Sequence

String:

MAASVCSGLL GPRVLSWSRE LPCAWRALHT SPVCAKNRAA RVRVSKGDKP VTYEEAHAPH YIAHRKGWLS LHTGNLDGED HAAERTVED VFLRKFMWGT FPGCLADQLV LKRRGNQLEI CAVVLRQLSP HKYYFLVGYS ETLLSYFYKC PVRLHLQTVP S KVVYKYL

UniProtKB: Small ribosomal subunit protein uS3m

Macromolecule #28: Large ribosomal subunit protein bL32m

• Macromolecule: Name: Large ribosomal subunit protein bL32m / type: protein_or_peptide / ID: 28 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 21.437799 KDa

Sequence

String:

MALAMLVLVV SPWSAARGVL RNYWERLLRK LPQSRPGFPS PPWGPALAVQ GPAMFTEPAN DTSGSKENSS LLDSIFWMAA PKNRRTIEV NRCRRRNPQK LIKVKNNIDV CPECGHLKQK HVLCAYCYEK VCKETAEIRR QIGKQEGGPF KAPTIETVVL Y TGETPSEQ DQGKRIIERD RKRPSWFTQN

UniProtKB: Large ribosomal subunit protein bL32m

Macromolecule #29: Large ribosomal subunit protein bL33m

• Macromolecule: Name: Large ribosomal subunit protein bL33m / type: protein_or_peptide / ID: 29 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 7.635204 KDa

Sequence

String:

MFLSAVFFAK SKSKNILVRM VSEAGTGFCF NTKRNRLREK LTLLHYDPVV KQRVLFVEKK KIRSL

UniProtKB: Large ribosomal subunit protein bL33m

Macromolecule #30: Large ribosomal subunit protein bL34m

• Macromolecule: Name: Large ribosomal subunit protein bL34m / type: protein_or_peptide / ID: 30 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 10.183913 KDa

Sequence

String:

MAVLAGSLLG PTSRSAALLG GRWLQPRAWL GFPDAWGLPT PQQARGKARG NEYQPSNIKR KNKHGWVRRL STPAGVQVIL RRMLKGRKS LSH

UniProtKB: Large ribosomal subunit protein bL34m

Macromolecule #31: Large ribosomal subunit protein bL35m

• Macromolecule: Name: Large ribosomal subunit protein bL35m / type: protein_or_peptide / ID: 31 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 21.558488 KDa

Sequence

String:

MAASAFAGAV RAASGILRPL NILASSTYRN CVKNASLISA LSTGRFSHIQ TPVVSSTPRL TTSERNLTCG HTSVILNRMA PVLPSVLKL PVRSLTYFSA RKGKRKTVKA VIDRFLRLHC GLWVRRKAGY KKKLWKKTPA RKKRLREFVF CNKTQSKLLD K MTTSFWKR RNWYVDDPYQ KYHDRTNLKV

UniProtKB: Large ribosomal subunit protein bL35m

Macromolecule #32: Large ribosomal subunit protein bL36m

• Macromolecule: Name: Large ribosomal subunit protein bL36m / type: protein_or_peptide / ID: 32 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 11.809301 KDa

Sequence

String:

MANLFIRKMV NPLLYLSRHT VKPRALSTFL FGSIRGAAPV AVEPGAAVRS LLSPGLLPHL LPALGFKNKT VLKKRCKDCY LVKRRGRWY VYCKTHPRHK QRQM

UniProtKB: Large ribosomal subunit protein bL36m

Macromolecule #33: Large ribosomal subunit protein uL1m

• Macromolecule: Name: Large ribosomal subunit protein uL1m / type: protein_or_peptide / ID: 33 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 36.967746 KDa

Sequence

String:

MAAAVRCMGR ALIHHQRHSL SKMVYQTSLC SCSVNIRVPN RHFAAATKSA KKTKKGAKEK TPDEKKDEIE KIKAYPYMEG EPEDDVYLK RLYPRQIYEV EKAVHLLKKF QILDFTSPKQ SVYLDLTLDM ALGKKKNVEP FTSVLSLPYP FASEINKVAV F TENASEVK IAEENGAAFA GGTSLIQKIW DDEIVADFYV AVPEIMPELN RLRKKLNKKY PKLSRNSIGR DIPKMLELFK NG HEIKVDE ERENFLQTKI ATLDMSSDQI AANLQAVINE VCRHRPLNLG PFVVRAFLRS STSEGLLLKI DPLLPKEVKN EES EKEDA

UniProtKB: Large ribosomal subunit protein uL1m

Macromolecule #34: Large ribosomal subunit protein bL12m

• Macromolecule: Name: Large ribosomal subunit protein bL12m / type: protein_or_peptide / ID: 34 / Number of copies: 6 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 21.378164 KDa

Sequence

String:

MLPAAARPLW GPCLGLRAAA FRLARRQVPC VCAVRHMRSS GHQRCEALAG APLDNAPKEY PPKIQQLVQD IASLTLLEIS DLNELLKKT LKIQDVGLVP MGGVMSGAVP AAAAQEAVEE DIPIAKERTH FTVRLTEAKP VDKVKLIKEI KNYIQGINLV Q AKKLVESL PQEIKANVAK AEAEKIKAAL EAVGGTVVLE

UniProtKB: Large ribosomal subunit protein bL12m

Macromolecule #35: Large ribosomal subunit protein mL37

• Macromolecule: Name: Large ribosomal subunit protein mL37 / type: protein_or_peptide / ID: 35 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 48.183344 KDa

Sequence

String:

MALASGPARR ALAGSGQLGL GGFGAPRRGA YEWGVRSTRK SEPPPLDRVY EIPGLEPITF AGKMHFVPWL ARPIFPPWDR GYKDPRFYR SPPLHEHPLY KDQACYIFHH RCRLLEGVKQ ALWLTKTKLI EGLPEKVLSL VDDPRNHIEN QDECVLNVIS H ARLWQTTE EIPKRETYCP VIVDNLIQLC KSQILKHPSL ARRICVQNST FSATWNRESL LLQVRGSGGA RLSTKDPLPT IA SREEIEA TKNHVLETFY PISPIIDLHE CNIYDVKNDT GFQEGYPYPY PHTLYLLDKA NLRPHRLQPD QLRAKMILFA FGS ALAQAR LLYGNDAKVL EQPVVVQSVG TDGRVFHFLV FQLNTTDLDC NEGVKNLAWV DSDQLLYQHF WCLPVIKKRV VVEP VGPVG FKPETFRKFL ALYLHGAA

UniProtKB: Large ribosomal subunit protein mL37

Macromolecule #36: Large ribosomal subunit protein mL38

• Macromolecule: Name: Large ribosomal subunit protein mL38 / type: protein_or_peptide / ID: 36 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 44.65943 KDa

Sequence

String:

MAAPWWRAAL CECRRWRGFS TSAVLGRRTP PLGPMPNSDI DLSNLERLEK YRSFDRYRRR AEQEAQAPHW WRTYREYFGE KTDPKEKID IGLPPPKVSR TQQLLERKQA IQELRANVEE ERAARLRTAS VPLDAVRAEW ERTCGPYHKQ RLAEYYGLYR D LFHGATFV PRVPLHVAYA VGEDDLMPVY CGNEVTPTEA AQAPEVTYEA EEGSLWTLLL TSLDGHLLEP DAEYLHWLLT NI PGNRVAE GQVTCPYLPP FPARGSGIHR LAFLLFKQDQ PIDFSEDARP SPCYQLAQRT FRTFDFYKKH QETMTPAGLS FFQ CRWDDS VTYIFHQLLD MREPVFEFVR PPPYHPKQKR FPHRQPLRYL DRYRDSHEPT YGIY

UniProtKB: Large ribosomal subunit protein mL38

Macromolecule #37: Large ribosomal subunit protein mL39

• Macromolecule: Name: Large ribosomal subunit protein mL39 / type: protein_or_peptide / ID: 37 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 38.764785 KDa

Sequence

String:

MEALAMGSRA LRLWLVAPGG GIKWRFIATS SASQLSPTEL TEMRNDLFNK EKARQLSLTP RTEKIEVKHV GKTDPGTVFV MNKNISTPY SCAMHLSEWY CRKSILALVD GQPWDMYKPL TKSCEIKFLT FKDCDPGEVN KAYWRSCAMM MGCVIERAFK D EYMVNLVR APEVPVISGA FCYDVVLDSK LDEWMPTKEN LRSFTKDAHA LIYKDLPFET LEVEAKVALE IFQHSKYKVD FI EEKASQN PERIVKLHRI GDFIDVSEGP LIPRTSICFQ YEVSAVHNLQ PTQPSLIRRF QGVSLPVHLR AHFTIWDKLL ERS RKMVTE DQSKATEECT ST

UniProtKB: Large ribosomal subunit protein mL39

Macromolecule #38: Large ribosomal subunit protein mL40

• Macromolecule: Name: Large ribosomal subunit protein mL40 / type: protein_or_peptide / ID: 38 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 24.534422 KDa

Sequence

String:

MTASVLRSIS LALRPTSGLL GTWQTQLRET HQRASLLSFW ELIPMRSEPL RKKKKVDPKK DQEAKERLKR KIRKLEKATQ ELIPIEDFI TPLKFLDKAR ERPQVELTFE ETERRALLLK KWSLYKQQER KMERDTIRAM LEAQQEALEE LQLESPKLHA E AIKRDPNL FPFEKEGPHY TPPIPNYQPP EGRYNDITKV YTQVEFKR

UniProtKB: Large ribosomal subunit protein mL40

Macromolecule #39: Large ribosomal subunit protein mL41

• Macromolecule: Name: Large ribosomal subunit protein mL41 / type: protein_or_peptide / ID: 39 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 15.404708 KDa

Sequence

String:

MGVLAAAARC LVRGADRMSK WTSKRGPRSF RGRKGRGAKG IGFLTSGWRF VQIKEMVPEF VVPDLTGFKL KPYVSYLAPE SEETPLTAA QLFSEAVAPA IEKDFKDGTF DPDNLEKYGF EPTQEGKLFQ LYPRNFLR

UniProtKB: Large ribosomal subunit protein mL41

Macromolecule #40: Large ribosomal subunit protein mL42

• Macromolecule: Name: Large ribosomal subunit protein mL42 / type: protein_or_peptide / ID: 40 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 16.691176 KDa

Sequence

String:

MAVAAVKWVM SKRTILKHLF PVQNGALYCV CHKSTYSPLP DDYNCNVELA LTSDGRTIVC YHPSVDIPYE HTKPIPRPDP VHNNEETHD QVLKTRLEEK VEHLEEGPMI EQLSKMFFTT KHRWYPHGRY HRCRKNLNPP KDR

UniProtKB: Large ribosomal subunit protein mL42

Macromolecule #41: Large ribosomal subunit protein mL43

• Macromolecule: Name: Large ribosomal subunit protein mL43 / type: protein_or_peptide / ID: 41 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 23.352633 KDa

Sequence

String:

(ACE)TARGTPSRF LASVLHNGLG RYVQQLQRLS FSVSRDGASS RGAREFVERE VIDFARRNPG VVIYVNSRPC CVPRVV AEY LNGAVREESI HCKSVEEIST LVQKLADQSG LDVIRIRKPF HTDNPSIQGQ WHPFTNKPTT FRGLRPREVQ DPAPAQD TG LRLSAVAPQI LLPGWPDPPD LPTVDPISSS LTSAPAPMLS AVSCLPIVPA LTTVCSA

UniProtKB: Large ribosomal subunit protein mL43

Macromolecule #42: Large ribosomal subunit protein mL44

• Macromolecule: Name: Large ribosomal subunit protein mL44 / type: protein_or_peptide / ID: 42 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 37.583312 KDa

Sequence

String:

MASGLVRLLQ QGHRCLLAPV APKLVPPVRG VKKGFRAAFR FQKELERQRL LRCPPPPVRR SEKPNWDYHA EIQAFGHRLQ ENFSLDLLK TAFVNSCYIK SEEAKRQQLG IEKEAVLLNL KSNQELSEQG TSFSQTCLTQ FLEDEYPDMP TEGIKNLVDF L TGEEVVCH VARNLAVEQL TLSEEFPVPP AVLQQTFFAV IGALLQSSGP ERTALFIRDF LITQMTGKEL FEMWKIINPM GL LVEELKK RNVSAPESRL TRQSGGTTAL PLYFVGLYCD KKLIAEGPGE TVLVAEEEAA RVALRKLYGF TENRRPWNYS KPK ETLRAE KSITAS

UniProtKB: Large ribosomal subunit protein mL44

Macromolecule #43: Large ribosomal subunit protein mL46

• Macromolecule: Name: Large ribosomal subunit protein mL46 / type: protein_or_peptide / ID: 43 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 31.748107 KDa

Sequence

String:

MAAPVRRTLL GVAGGWRRFE RLWAGSLSSR SLALAAAPSS NGSPWRLLGA LCLQRPPVVS KPLTPLQEEM ASLLQQIEIE RSLYSDHEL RALDENQRLA KKKADLHDEE DEQDILLAQD LEDMWEQKFL QFKLGARITE ADEKNDRTSL NRKLDRNLVL L VREKFGDQ DVWILPQAEW QPGETLRGTA ERTLATLSEN NMEAKFLGNA PCGHYTFKFP QAMRTESNLG AKVFFFKALL LT GDFSQAG NKGHHVWVTK DELGDYLKPK YLAQVRRFVS DL

UniProtKB: Large ribosomal subunit protein mL46

Macromolecule #44: Large ribosomal subunit protein mL48

• Macromolecule: Name: Large ribosomal subunit protein mL48 / type: protein_or_peptide / ID: 44 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 23.970814 KDa

Sequence

String:

MSGTLEKVLC LRNNTIFKQA FSLLRFRTSG EKPIYSVGGI LLSISRPYKT KPTHGIGKYK HLIKAEEPKK KKGKVEVRAI NLGTDYEYG VLNIHLTAYD MTLAESYAQY VHNLCNSLSI KVEESYAMPT KTIEVLQLQD QGSKMLLDSV LTTHERVVQI S GLSATFAE IFLEIIQSSL PEGVRLSVKE HTEEDFKGRF KARPELEELL AKLK

UniProtKB: Large ribosomal subunit protein mL48

Macromolecule #45: Large ribosomal subunit protein mL49

• Macromolecule: Name: Large ribosomal subunit protein mL49 / type: protein_or_peptide / ID: 45 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 19.225043 KDa

Sequence

String:

MAATMFRATL RGWRTGVQRG CGLRLLSQTQ GPPDYPRFVE SVDEYQFVER LLPATRIPDP PKHEHYPTPS GWQPPRDPPP NLPYFVRRS RMHNIPVYKD ITHGNRQMTV IRKVEGDIWA LQKDVEDFLS PLLGKTPVTQ VNEVTGTLRI KGYFDQELKA W LLEKGF

UniProtKB: Large ribosomal subunit protein mL49

Macromolecule #46: Large ribosomal subunit protein mL50

• Macromolecule: Name: Large ribosomal subunit protein mL50 / type: protein_or_peptide / ID: 46 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 18.349943 KDa

Sequence

String:

MAARSVSGIT RRVFMWTVSG TPCREFWSRF RKEKEPVVVE TVEEKKEPIL VCPPLRSRAY TPPEDLQSRL ESYVKEVFGS SLPSNWQDI SLEDSRLKFN LLAHLADDLG HVVPNSRLHQ MCRVRDVLDF YNVPIQDRSK FDELSASNLP PNLKITWSY

UniProtKB: Large ribosomal subunit protein mL50

Macromolecule #47: Large ribosomal subunit protein mL51

• Macromolecule: Name: Large ribosomal subunit protein mL51 / type: protein_or_peptide / ID: 47 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 15.125917 KDa

Sequence

String:

MAGNLLSGAG RRLWDWVPLA CRSFSLGVPR LIGIRLTLPP PKVVDRWNEK RAMFGVYDNI GILGNFEKHP KELIRGPIWL RGWKGNELQ RCIRKRKMVG SRMFADDLHN LNKRIRYLYK HFNRHGKFR

UniProtKB: Large ribosomal subunit protein mL51

Macromolecule #48: Large ribosomal subunit protein mL52

• Macromolecule: Name: Large ribosomal subunit protein mL52 / type: protein_or_peptide / ID: 48 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 13.682658 KDa

Sequence

String:

MAALGTVLFT GVRRLHCSVA AWAGGQWRLQ QGLAANPSGY GPLTELPDWS YADGRPAPPM KGQLRRKAER ETFARRVVLL SQEMDAGLQ AWQLRQQKLQ EEQRKQENAL KPKGASLKSP LPSQ

UniProtKB: Large ribosomal subunit protein mL52

Macromolecule #49: Large ribosomal subunit protein mL53

• Macromolecule: Name: Large ribosomal subunit protein mL53 / type: protein_or_peptide / ID: 49 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 12.020701 KDa

Sequence

String:

(ACE)AAALARLGL RPVKQVRVQF CPFEKNVEST RTFLQTVSSE KVRSTNLNCS VIADVRHDGS EPCVDVLFGD GHRLIM RGA HLTALEMLTA FASHIRARDA AGSGDKPGAD TGR

UniProtKB: Large ribosomal subunit protein mL53

Macromolecule #50: Large ribosomal subunit protein mL54

• Macromolecule: Name: Large ribosomal subunit protein mL54 / type: protein_or_peptide / ID: 50 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 15.844178 KDa

Sequence

String:

MATKRLFGAT RTWAGWGAWE LLNPATSGRL LARDYAKKPV MKGAKSGKGA VTSEALKDPD VCTDPVQLTT YAMGVNIYKE GQDVPLKPD AEYPEWLFEM NLGPPKTLEE LDPESREYWR RLRKQNIWRH NRLSKNKRL

UniProtKB: Large ribosomal subunit protein mL54

Macromolecule #51: Large ribosomal subunit protein mL55

• Macromolecule: Name: Large ribosomal subunit protein mL55 / type: protein_or_peptide / ID: 51 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 15.160433 KDa

Sequence

String:

MAAVGSLLGR LRQSTVKATG PALRRLHTSS WRADSSRASL TRVHRQAYAR LYPVLLVKQD GSTIHIRYRE PRRMLAMPID LDTLSPEER RARLRKREAQ LQSRKEYEQE LSDDLHVERY RQFWTRTKK

UniProtKB: Large ribosomal subunit protein mL55

Macromolecule #52: Large ribosomal subunit protein mL63

• Macromolecule: Name: Large ribosomal subunit protein mL63 / type: protein_or_peptide / ID: 52 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 12.292333 KDa

Sequence

String:

MFLTALLWRG RIPGRQWIGK HRRPRFVSLR AKQNMIRRLE IEAENHYWLS MPYMTREQER GHAAVRRREA FEAIKAAATS KFPPHRFIA DQLDHLNVTK KWS

UniProtKB: Large ribosomal subunit protein mL63

Macromolecule #53: Large ribosomal subunit protein mL62

• Macromolecule: Name: Large ribosomal subunit protein mL62 / type: protein_or_peptide / ID: 53 / Number of copies: 1 / Enantiomer: LEVO / EC number: peptidyl-tRNA hydrolase
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 23.674203 KDa

Sequence

String:

MAATRCLRWG LSRAGVWLLP PPARCPRRAL HKQKDGTEFK SIYSLDKLYP ESQGSDTAWR VPNGAKQADS DIPLDRLTIS YCRSSGPGG QNVNKVNSKA EVRFHLATAE WIAEPVRQKI AITHKNKINR LGELILTSES SRYQFRNLAD CLQKIRDMIT E ASQTPKEP TKEDVKLHRI RIENMNRERL RQKRIHSAVK TSRRVDMD

UniProtKB: Large ribosomal subunit protein mL62

Macromolecule #54: Large ribosomal subunit protein mL64

• Macromolecule: Name: Large ribosomal subunit protein mL64 / type: protein_or_peptide / ID: 54 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 25.426895 KDa

Sequence

String:

MAASVRQARS LLGVAATLAP GSRGYRARPP PRRRPGPRWP DPEDLLTPRW QLGPRYAAKQ FARYGAASGV VPGSLWPSPE QLRELEAEE REWYPSLATM QESLRVKQLA EEQKRREREQ HIAECMAKMP QMIVNWQQQQ RENWEKAQAD KERRARLQAE A QELLGYQV DPRSARFQEL LQDLEKKERK RLKEEKQKRK KEARAAALAA AVAQDPAASG APSS

UniProtKB: Large ribosomal subunit protein mL64

Macromolecule #55: Large ribosomal subunit protein mL66

• Macromolecule: Name: Large ribosomal subunit protein mL66 / type: protein_or_peptide / ID: 55 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 22.224078 KDa

Sequence

String:

MAALKALVSG CGRLLRGLLA GPAATSWSRL PARGFREVVE TQEGKTTIIE GRITATPKES PNPPNPSGQC PICRWNLKHK YNYDDVLLL SQFIRPHGGM LPRKITGLCQ EEHRKIEECV KMAHRAGLLP NHRPRLPEGV VPKSKPQLNR YLTRWAPGSV K PIYKKGPR WNRVRMPVGS PLLRDNVCYS RTPWKLYH

UniProtKB: Large ribosomal subunit protein mL66

Macromolecule #56: Large ribosomal subunit protein mL65

• Macromolecule: Name: Large ribosomal subunit protein mL65 / type: protein_or_peptide / ID: 56 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 50.429578 KDa

Sequence

String:

MAAARCWRPL LRGPRLSLHT AANAAATATE TTCQDVAATP VARYPPIVAS MTADSKAARL RRIERWQATV HAAESVDEKL RILTKMQFM KYMVYPQTFA LNADRWYQYF TKTVFLSGLP PPPAEPEPEP EPEPEPALDL AALRAVACDC LLQEHFYLRR R RRVHRYEE SEVISLPFLD QLVSTLVGLL SPHNPALAAA ALDYRCPVHF YWVRGEEIIP RGHRRGRIDD LRYQIDDKPN NQ IRISKQL AEFVPLDYSV PIEIPTIKCK PDKLPLFKRQ YENHIFVGSK TADPCCYGHT QFHLLPDKLR RERLLRQNCA DQI EVVFRA NAIASLFAWT GAQAMYQGFW SEADVTRPFV SQAVITDGKY FSFFCYQLNT LALTTQADQN NPRKNICWGT QSKP LYETI EDNDVKGFND DVLLQIVHFL LNRPKEEKSQ LLEN

UniProtKB: Large ribosomal subunit protein mL65

Macromolecule #57: Small ribosomal subunit protein uS5m

• Macromolecule: Name: Small ribosomal subunit protein uS5m / type: protein_or_peptide / ID: 57 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 48.094594 KDa

Sequence

String:

MATAVRAVGC LPVLCSGTAG HLLGRQCSLN TLPAASILAW KSVLGNGHLS SLGTRDTHPY ASLSRALQTQ CCISSPSHLM SQQYRPYSF FTKLTADELW KGALAETGAG AKKGRGKRTK KKKRKDLNRG QIIGEGRYGF LWPGLNVPLM KNGAVQTIAQ R SKEEQEKV EADMIQQREE WDRKKKMKVK RERGWSGNSW GGISLGPPDP GPCGETYEDF DTRILEVRNV FTMTAKEGRK KS IRVLVAV GNGKGAAGFS IGKATDRMDA FRKAKNRAVH HLHYIERYED HTIFHDISLR FKRTHIKMKK QPKGYGLRCH RAI ITICRL IGIKDMYAKV SGSINMLSLT QGLFRGLSRQ ETHQQLADKK GLHVVEIREE CGPLPIVVAS PRGPLRKDPE PEDE VPDVK LDWEDVKTAQ GMKRSVWSNL KRAAT

UniProtKB: Small ribosomal subunit protein uS5m

Macromolecule #58: Small ribosomal subunit protein bS6m

• Macromolecule: Name: Small ribosomal subunit protein bS6m / type: protein_or_peptide / ID: 58 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 14.250588 KDa

Sequence

String:

MPRYELALIL KAMQRPETAA TLKRTIEALM DRGAIVRDLE NLGERALPYR ISAHSQQHNR GGYFLVDFYA PTAAVESMVE HLSRDIDVI RGNIVKHPLT QELKECEGIV PVPLAEKLYS TKKRKK

UniProtKB: Small ribosomal subunit protein bS6m

Macromolecule #59: Small ribosomal subunit protein uS7m

• Macromolecule: Name: Small ribosomal subunit protein uS7m / type: protein_or_peptide / ID: 59 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 28.186154 KDa

Sequence

String:

MAAPAVKVAR GWSGLALGVR RAVLQLPGLT QVRWSRYSPE FKDPLIDKEY YRKPVEELTE EEKYVRELKK TQLIKAAPAG KTSSVFEDP VISKFTNMMM IGGNKVLARS LMIQTLEAVK RKQFEKYHAA SAEEQATIER NPYTIFHQAL KNCEPMIGLV P ILKGGRFY QVPVPLPDRR RRFLAMKWMI TECRDKKHQR TLMPEKLSHK LLEAFHNQGP VIKRKHDLHK MAEANRALAH YR WW

UniProtKB: Small ribosomal subunit protein uS7m

Macromolecule #60: Small ribosomal subunit protein uS9m

• Macromolecule: Name: Small ribosomal subunit protein uS9m / type: protein_or_peptide / ID: 60 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 45.909859 KDa

Sequence

String:

MAAPCVSYGG AVSYRLLLWG RGSLARKQGL WKTAAPELQT NVRSQILRLR HTAFVIPKKN VPTSKRETYT EDFIKKQIEE FNIGKRHLA NMMGEDPETF TQEDIDRAIA YLFPSGLFEK RARPVMKHPE QIFPRQRAIQ WGEDGRPFHY LFYTGKQSYY S LMHDVYGM LLNLEKHQSH LQAKSLLPEK TVTRDVIGSR WLIKEELEEM LVEKLSDLDY MQFIRLLEKL LTSQCGAAEE EF VQRFRRS VTLESKKQLI EPVQYDEQGM AFSKSEGKRK TAKAEAIVYK HGSGRIKVNG IDYQLYFPIT QDREQLMFPF HFV DRLGKH DVTCTVSGGG RSAQAGAIRL AMAKALCSFV TEDEVEWMRQ AGLLTTDPRV RERKKPGQEG ARRKFTWKKR

UniProtKB: Small ribosomal subunit protein uS9m

Macromolecule #61: Small ribosomal subunit protein uS10m

• Macromolecule: Name: Small ribosomal subunit protein uS10m / type: protein_or_peptide / ID: 61 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 23.0335 KDa

Sequence

String:

MAARTAFGAV CRRLWQGLGN FSVNTSKGNT AKNGGLLLST NMKWVQFSNL HVDVPKDLTK PVVTISDEPD ILYKRLSVLV KGHDKAVLD SYEYFAVLAA KELGISIKVH EPPRKIERFT LLQSVHIYKK HRVQYEMRTL YRCLELEHLT GSTADVYLEY I QRNLPEGV AMEVTKTQLE QLPEHIKEPI WETLSEEKEE SKS

UniProtKB: Small ribosomal subunit protein uS10m

Macromolecule #62: Small ribosomal subunit protein uS11m

• Macromolecule: Name: Small ribosomal subunit protein uS11m / type: protein_or_peptide / ID: 62 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 20.663805 KDa

Sequence

String:

MQAVRNAGSR FLRSWTWPQT AGRVVARTPA GTICTGARQL QDAAAKQKVE QNAAPSHTKF SIYPPIPGEE SSLRWAGKKF EEIPIAHIK ASHNNTQIQV VSASNEPLAF ASCGTEGFRN AKKGTGIAAQ TAGIAAAARA KQKGVIHIRV VVKGLGPGRL S AMHGLIMG GLEVISITDN TPIPH(5F0)GCRP RKARKL

UniProtKB: Small ribosomal subunit protein uS11m

Macromolecule #63: Small ribosomal subunit protein uS12m

• Macromolecule: Name: Small ribosomal subunit protein uS12m / type: protein_or_peptide / ID: 63 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 15.200947 KDa

Sequence

String:

MSWSGLLHGL NTSLTCGPAL VPRLWATCSM ATLNQMHRLG PPKRPPRKLG PTEGRPQLKG VVLCTFTRKP KKPNSANRKC CRVRLSTGR EAVCFIPGEG HTLQEHQIVL VEGGRTQDLP GVKLTVVRGK YDCGHVQKK

UniProtKB: Small ribosomal subunit protein uS12m

Macromolecule #64: Small ribosomal subunit protein uS14m

• Macromolecule: Name: Small ribosomal subunit protein uS14m / type: protein_or_peptide / ID: 64 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 15.168788 KDa

Sequence

String:

MAAFMLGSLL RTFKQMVPSS ASGQVRSHYV DWRMWRDVKR RKMAYEYADE RLRINSLRKN TILPKILQDV ADEEIAALPR DSCPVRIRN RCVMTSRPRG VKRRWRLSRI VFRHLADHGQ LSGIQRATW

UniProtKB: Small ribosomal subunit protein uS14m

Macromolecule #65: Small ribosomal subunit protein uS15m

• Macromolecule: Name: Small ribosomal subunit protein uS15m / type: protein_or_peptide / ID: 65 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 29.903293 KDa

Sequence

String:

MLRVAWRTLS LIRTRAVTQV LVPGLPGGGS AKFPFNQWGL QPRSLLLQAA RGYVVRKPAQ SRLDDDPPPS TLLKDYQNVP GIEKVDDVV KRLLSLEMAN KKEMLKIKQE QFMKKIVANP EDTRSLEARI IALSVKIRSY EEHLEKHRKD KAHKRYLLMS I DQRKKMLK NLRNTNYDVF EKICWGLGIE YTFPPLYYRR AHRRFVTKKA LCIRVFQETQ KLKKRRRALK AAAAAQKQAK RR NPDSPAK AIPKTLKDSQ

UniProtKB: Small ribosomal subunit protein uS15m

Macromolecule #66: Small ribosomal subunit protein bS16m

• Macromolecule: Name: Small ribosomal subunit protein bS16m / type: protein_or_peptide / ID: 66 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 15.371899 KDa

Sequence

String:

MVHLTTLLCK AYRGGHLTIR LALGGCTNRP FYRIVAAHNK CPRDGRFVEQ LGSYDPLPNS HGEKLVALNL DRIRHWIGCG AHLSKPMEK LLGLAGFFPL HPMMITNAER LRRKRAREVL LASQKTDAEA TDTEATET

UniProtKB: Small ribosomal subunit protein bS16m

Macromolecule #67: Small ribosomal subunit protein uS17m

• Macromolecule: Name: Small ribosomal subunit protein uS17m / type: protein_or_peptide / ID: 67 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 14.526078 KDa

Sequence

String:

MSVVRSSVHA RWIVGKVIGT KMQKTAKVRV TRLVLDPYLL KYFNKRKTYF AHDALQQCTV GDIVLLRALP VPRAKHVKHE LAEIVFKVG KVIDPVTGKP CAGTTYLESP LSSETTQLSK NLEELNISSA Q

UniProtKB: Small ribosomal subunit protein uS17m

Macromolecule #68: Small ribosomal subunit protein mS40

• Macromolecule: Name: Small ribosomal subunit protein mS40 / type: protein_or_peptide / ID: 68 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 29.440629 KDa

Sequence

String:

MAASVLNTVL RRLPMLSLFR GSHRVQVPLQ TLCTKAPSEE DSLSSVPISP YKDEPWKYLE SEEYQERYGS RPVWADYRRN HKGGVPPQR TRKTCIRRNK VVGNPCPICR DHKLHVDFRN VKLLEQFVCA HTGIIFYAPY TGVCVKQHKR LTQAIQKARD H GLLIYHIP QVEPRDLDFS TSHGAVSATP PAPTLVSGDP WYPWYNWKQP PERELSRLRR LYQGHLQEES GPPPESMPKM PP RTPAEAS STGQTGPQSA L

UniProtKB: Small ribosomal subunit protein mS40

Macromolecule #69: Small ribosomal subunit protein bS18m

• Macromolecule: Name: Small ribosomal subunit protein bS18m / type: protein_or_peptide / ID: 69 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 15.876786 KDa

Sequence

String:

MAAVVAVCGG LGRKKLTHLV TAAVSLTHPG THTVLWRRGC SQQVSSNEDL PISMENPYKE PLKKCILCGK HVDYKNVQLL SQFVSPFTG CIYGRHITGL CGKKQKEITK AIKRAQIMGF MPVTYKDPAY LKDPKVCNIR YRE

UniProtKB: Small ribosomal subunit protein bS18m

Macromolecule #70: Small ribosomal subunit protein bS21m

• Macromolecule: Name: Small ribosomal subunit protein bS21m / type: protein_or_peptide / ID: 70 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 10.659494 KDa

Sequence

String:

(ACE)AKHLKFIAR TVMVQEGNVE SAYRTLNRIL TMDGLIEDIK HRRYYEKPCR RRQRESYERC RRIYNMEMAR KINFLM RKN RADPWQGC

UniProtKB: Small ribosomal subunit protein bS21m

Macromolecule #71: Small ribosomal subunit protein mS22

• Macromolecule: Name: Small ribosomal subunit protein mS22 / type: protein_or_peptide / ID: 71 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 41.337316 KDa

Sequence

String:

MAPLGTTVLL WSLLRSSPGV ERVCFRARIQ PWHGGLLQPL PCSFEMGLPR RRFSSEAAES GSPETKKPTF MDEEVQSILT KMTGLNLQK TFKPAIQELK PPTYKLMTQA QLEEATRQAV EAAKVRLKMP PVLEERVPIN DVLAEDKILE GTETTKYVFT D ISYSIPHR ERFIVVREPS GTLRKASWEE RDRMIQVYFP KEGRKILTPI IFKEENLRTM YSQDRHVDVL NLCFAQFEPD ST EYIKVHH KTYEDIDKRG KYDLLRSTRY FGGMVWYFVN NKKIDGLLID QIQRDLIDDA TNLVQLYHVL HPDGQSAQGA KDQ AAEGIN LIKVFAKTEA QKGAYIELTL QTYQEALSRH SAAS

UniProtKB: Small ribosomal subunit protein mS22

Macromolecule #72: Small ribosomal subunit protein mS23

• Macromolecule: Name: Small ribosomal subunit protein mS23 / type: protein_or_peptide / ID: 72 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 21.805664 KDa

Sequence

String:

MAGSRLETVG SIFSRTRDLV RAGVLKEKPL WFDVYDAFPP LREPVFQRPR VRYGKAKAPI QDIWYHEDRI RAKFYSVYGS GQRAFDLFN PNFKSTCQRF VEKYTELQKL GETDEEKLFV ETGKALLAEG VILRRVGEAR TQHGGSHVSR KSEHLSVRPQ T ALEENETQ KEVPQDQHLE APADQSKGLL PP

UniProtKB: Small ribosomal subunit protein mS23

Macromolecule #73: Small ribosomal subunit protein mS25

• Macromolecule: Name: Small ribosomal subunit protein mS25 / type: protein_or_peptide / ID: 73 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 20.146428 KDa

Sequence

String:

MPMKGRFPIR RTLQYLSQGN VVFKDSVKVM TVNYNTHGEL GEGARKFVFF NIPQIQYKNP WVQIMMFKNM TPSPFLRFYL DSGEQVLVD VETKSNKEIM EHIRKILGKN EETLREEEEE KKQLSHPANF GPRKYCLREC ICEVEGQVPC PSLVPLPKEM R GKYKAALK ADAQD

UniProtKB: Small ribosomal subunit protein mS25

Macromolecule #74: Small ribosomal subunit protein mS26

• Macromolecule: Name: Small ribosomal subunit protein mS26 / type: protein_or_peptide / ID: 74 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 24.25982 KDa

Sequence

String:

MLRALSRLGA GTPCRPRAPL VLPARGRKTR HDPLAKSKIE RVNMPPAVDP AEFFVLMERY QHYRQTVRAL RMEFVSEVQR KVHEARAGV LAERKALKDA AEHRELMAWN QAENRRLHEL RIARLRQEER EQEQRQALEQ ARKAEEVQAW AQRKEREVLQ L QEEVKNFI TRENLEARVE AALDSRKNYN WAITREGLVV RPQRRDS

UniProtKB: Small ribosomal subunit protein mS26

Macromolecule #75: Small ribosomal subunit protein mS27

• Macromolecule: Name: Small ribosomal subunit protein mS27 / type: protein_or_peptide / ID: 75 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 47.669262 KDa

Sequence

String:

MAASIVRRGM LLARQVVLPQ LSPAGKRYLL SSAYVDSHKW EAREKEHYCL ADLASLMDKT FERKLPVSSL TISRLIDNIS SREEIDHAE YYLYKFRHSP NCWYLRNWTI HTWIRQCLKY DAQDKALYTL VNKVQYGIFP DNFTFNLLMD SFIKKENYKD A LSVVFEVM MQEAFEVPST QLLSLYVLFH CLAKKTDFSW EEERNFGASL LLPGLKQKNS VGFSSQLYGY ALLGKVELQQ GL RAVYHNM PLIWKPGYLD RALQVMEKVA ASPEDIKLCR EALDVLGAVL KALTSADGAS EEQSQNDEDN QGSEKLVEQL DIE ETEQSK LPQYLERFKA LHSKLQALGK IESEGLLSLT TQLVKEKLST CEAEDIATYE QNLQQWHLDL VQLIQREQQQ REQA KQEYQ AQKAAKASA

UniProtKB: Small ribosomal subunit protein mS27

Macromolecule #76: Small ribosomal subunit protein bS1m

• Macromolecule: Name: Small ribosomal subunit protein bS1m / type: protein_or_peptide / ID: 76 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 20.878846 KDa

Sequence

String:

MAALCRTRAV AAESHFLRVF LFFRPFRGVG TESGSESGSS NAKEPKTRAG GFASALERHS ELLQKVEPLQ KGSPKNVESF ASMLRHSPL TQMGPAKDKL VIGRIFHIVE NDLYIDFGGK FHCVCRRPEV DGEKYQKGTR VRLRLLDLEL TSRFLGATTD T TVLEANAV LLGIQESKDS RSKEEHHEK

UniProtKB: Small ribosomal subunit protein bS1m

Macromolecule #77: Small ribosomal subunit protein mS29

• Macromolecule: Name: Small ribosomal subunit protein mS29 / type: protein_or_peptide / ID: 77 / Number of copies: 1 / Enantiomer: LEVO; EC number: Hydrolases; Acting on acid anhydrides; Acting on GTP to facilitate cellular and subcellular movement
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 45.634406 KDa

Sequence

String:

MMLKGITRLI SRIHKLDPGR FLHMGTQARQ SIAAHLDNQV PVESPRAISR TNENDPAKHG DQHEGQHYNI SPQDLETVFP HGLPPRFVM QVKTFSEACL MVRKPALELL HYLKNTSFAY PAIRYLLYGE KGTGKTLSLC HVIHFCAKQD WLILHIPDAH L WVKNCRDL LQSSYNKQRF DQPLEASTWL KNFKTTNERF LNQIKVQEKY VWNKRESTEK GSPLGEVVEQ GITRVRNATD AV GIVLKEL KRQSSLGMFH LLVAVDGINA LWGRTTLKRE DKSPIAPEEL ALVHNLRKMM KNDWHGGAIV SALSQTGSLF KPR KAYLPQ ELLGKEGFDA LDPFIPILVS NYNPKEFESC IQYYLENNWL QHEKAPTEEG KKELLFLSNA NPSLLERHCA YL

UniProtKB: Small ribosomal subunit protein mS29

Macromolecule #78: Small ribosomal subunit protein mS31

• Macromolecule: Name: Small ribosomal subunit protein mS31 / type: protein_or_peptide / ID: 78 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 45.391473 KDa

Sequence

String:

MFPRVSTFLP LRPLSRHPLS SGSPETSAAA IMLLTVRHGT VRYRSSALLA RTKNNIQRYF GTNSVICSKK DKQSVRTEET SKETSESQD SEKENTKKDL LGIIKGMKVE LSTVNVRTTK PPKRRPLKSL EATLGRLRRA TEYAPKKRIE PLSPELVAAA S AVADSLPF DKQTTKSELL SQLQQHEEES RAQRDAKRPK ISFSNIISDM KVARSATARV RSRPELRIQF DEGYDNYPGQ EK TDDLKKR KNIFTGKRLN IFDMMAVTKE APETDTSPSL WDVEFAKQLA TVNEQPLQNG FEELIQWTKE GKLWEFPINN EAG FDDDGS EFHEHIFLEK HLESFPKQGP IRHFMELVTC GLSKNPYLSV KQKVEHIEWF RNYFNEKKDI LKESNIQFN

UniProtKB: Small ribosomal subunit protein mS31

Macromolecule #79: Small ribosomal subunit protein mS33

• Macromolecule: Name: Small ribosomal subunit protein mS33 / type: protein_or_peptide / ID: 79 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 12.657776 KDa

Sequence

String:

MSSLSEYAFR MSRLSARLFG EVTRPTNSKS MKVVKLFSEL PLAKKKETYD WYPNHHTYAE LMQTLRFLGL YRDEHQDFMD EQKRLKKLR GKEKPKKGEG KRAAKRK

UniProtKB: Small ribosomal subunit protein mS33

Macromolecule #80: Small ribosomal subunit protein mS34

• Macromolecule: Name: Small ribosomal subunit protein mS34 / type: protein_or_peptide / ID: 80 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 25.564354 KDa

Sequence

String:

ARKKVRPRLI AELARRVRAL REQLNRPRDS QLYAVDYETL TRPFSGRRLP VRAWADVRRE SRLLQLLGRL PLFGLGRLVT RKSWLWQHD EPCYWRLTRV RPDYTAQNLD HGKAWGILTF KGKTESEARE IEHVMYHDWR LVPKHEEEAF TAFTPAPEDS L ASVPYPPL LRAMIIAERQ KNGDTSTEEP MLNVQRIRME PWDYPAKQED KGRAKGTPV

UniProtKB: Small ribosomal subunit protein mS34

Macromolecule #81: Small ribosomal subunit protein mS35

• Macromolecule: Name: Small ribosomal subunit protein mS35 / type: protein_or_peptide / ID: 81 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 36.898328 KDa

Sequence

String:

MAAAALPAWL SLQSRARTLR AFSTAVYSAT PVPTPSLPER TPGNERPPRR KALPPRTEKM AVDQDWPSVY PVAAPFKPSA VPLPVRMGY PVKKGVPMAK EGNLELLKIP NFLHLTPVAI KKHCEALKDF CTEWPAALDS DEKCEKHFPI EIDSTDYVSS G PSVRNPRA RVVVLRVKLS SLNLDDHAKK KLIKLVGERY CKTTDVLTIK TDRCPLRRQN YDYAVYLLTV LYHESWNTEE WE KSKTEAD MEEYIWENSS SERNILETLL QMKAAEKNME INKEELLGTK EIEEYKKSVV SLKNEEENEN SISQYKESVK RLL NVT

UniProtKB: Small ribosomal subunit protein mS35

Macromolecule #82: Small ribosomal subunit protein mS37

• Macromolecule: Name: Small ribosomal subunit protein mS37 / type: protein_or_peptide / ID: 82 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 13.393661 KDa

Sequence

String:

(ACE)ATPSLRGRL ARFGNPRKPV LKPNKPLILA NRVGERRREK GEATCITEMS VMMACWKQNE FRDDACRKEI QGFLDC AAR AQEARKMRSI QETLGESGSL LPNKLNKLLQ RFPNKPYLS

UniProtKB: Small ribosomal subunit protein mS37

Macromolecule #83: Small ribosomal subunit protein bS22, mitochondrial

• Macromolecule: Name: Small ribosomal subunit protein bS22, mitochondrial / type: protein_or_peptide / ID: 83 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 22.395326 KDa

Sequence

String:

MLLGRLTSQL LRAVPWAGGR PPWPVSGVLG SRVCGPLYST SPAGPGRAAS LPRKGAQLEL EEMLVPRKMS VSPLESWLTA RCFLPRLDT GTAGTVAPPQ SYQCPPSQIG EGAEQGDEGV ADAPQIQCKN VLKIRRRKMN HHKYRKLVKK TRFLRRKVQE G RLRRKQIK FEKDLRRIWL KAGLKEAPEG WQTPKIYLRG K

UniProtKB: Small ribosomal subunit protein bS22, mitochondrial

Macromolecule #84: Small ribosomal subunit protein mS39

• Macromolecule: Name: Small ribosomal subunit protein mS39 / type: protein_or_peptide / ID: 84 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 78.648547 KDa

Sequence

String:

MAVVSAVRWL GLRSRLGQPL TGRRAGLCEQ ARSCRFYSGS ATLSKVEGTD VTGIEEVVIP KKKTWDKVAV LQALASTVNR DTTAVPYVF QDDPYLMPAS SLESRSFLLA KKSGENVAKF IINSYPKYFQ KDIAEPHIPC LMPEYFEPQI KDISEAALKE R IELRKVKA SVDMFDQLLQ AGTTVSLETT NSLLDLLCYY GDQEPSTDYH FQQTGQSEAL EEENDETSRR KAGHQFGVTW RA KNNAERI FSLMPEKNEH SYCTMIRGMV KHRAYEQALN LYTELLNNRL HADVYTFNAL IEATVCAINE KFEEKWSKIL ELL RHMVAQ KVKPNLQTFN TILKCLRRFH VFARSPALQV LREMKAIGIE PSLATYHHII RLFDQPGDPL KRSSFIIYDI MNEL MGKRF SPKDPDDDKF FQSAMSICSS LRDLELAYQV HGLLKTGDNW KFIGPDQHRN FYYSKFFDLI CLMEQIDVTL KWYED LIPS AYFPHSQTMI HLLQALDVAN RLEVIPKIWK DSKEYGHTFR SDLREEILML MARDKHPPEL QVAFADCAAD IKSAYE SQP IRQTAQDWPA TSLNCIAILF LRAGRTQEAW KMLGLFRKHN KIPRSELLNE LMDSAKVSNS PSQAIEVVEL ASAFSLP IC EGLTQRVMSD FAINQEQKEA LSNLTALTSD SDTDSSSDSD SDTSEGK

UniProtKB: Small ribosomal subunit protein mS39

Macromolecule #88: COX1 nascent chain

• Macromolecule: Name: COX1 nascent chain / type: protein_or_peptide / ID: 88 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 3.252 KDa

Sequence

String:

(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)

Macromolecule #89: Large ribosomal subunit protein mL45

• Macromolecule: Name: Large ribosomal subunit protein mL45 / type: protein_or_peptide / ID: 89 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 35.402918 KDa

Sequence

String:

MAAPIPQGFS CLSRFLGWWF RQPVLVTQSA AIVPVRTKKR FTPPIYQPKF KTEKEFMQHA RKAGLVIPPE KSDRSIHLAC TAGIFDAYV PPEGDARISS LSKEGLIERT ERMKKTMASQ VSIRRIKDYD ANFKIKDFPE KAKDIFIEAH LCLNNSDHDR L HTLVTEHC FPDMTWDIKY KTVRWSFVES LEPSHVVQVR CSSMMNQGNV YGQITVRMHT RQTLAIYDRF GRLMYGQEDV PK DVLEYVV FEKQLTNPYG SWRMHTKIVP PWAPPKQPIL KTVMIPGPQL KPEEEYEEAQ GEAQKPQLA

UniProtKB: Large ribosomal subunit protein mL45

Macromolecule #90: Mitochondrial inner membrane protein OXA1L

• Macromolecule: Name: Mitochondrial inner membrane protein OXA1L / type: protein_or_peptide / ID: 90 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 48.574633 KDa

Sequence

String:

MAMGLMCGRR ELLRLLQSGR RVHSVAGPSQ WLGKPLTTRL LFPAAPCCCR PHYLFLAASG PRSLSTSAIS FAEVQVQAPP VVAATPSPT AVPEVASGET ADVVQTAAEQ SFAELGLGSY TPVGLIQNLL EFMHVDLGLP WWGAIAACTV FARCLIFPLI V TGQREAAR IHNHLPEIQK FSSRIREAKL AGDHIEYYKA SSEMALYQKK HGIKLYKPLI LPVTQAPIFI SFFIALREMA NL PVPSLQT GGLWWFQDLT VSDPIYILPL AVTATMWAVL ELGAETGVQS SDLQWMRNVI RMMPLITLPI TMHFPTAVFM YWL SSNLFS LVQVSCLRIP AVRTVLKIPQ RVVHDLDKLP PREGFLESFK KGWKNAEMTR QLREREQRMR NQLELAARGP LRQT FTHNP LLQPGKDNPP NIPSSSSKPK SKYPWHDTLG

UniProtKB: Mitochondrial inner membrane protein OXA1L

Macromolecule #91: POTASSIUM ION

• Macromolecule: Name: POTASSIUM ION / type: ligand / ID: 91 / Number of copies: 54 / Formula: K
• Molecular weight: Theoretical: 39.098 Da

Macromolecule #92: MAGNESIUM ION

• Macromolecule: Name: MAGNESIUM ION / type: ligand / ID: 92 / Number of copies: 196 / Formula: MG
• Molecular weight: Theoretical: 24.305 Da

Macromolecule #93: VALINE

• Macromolecule: Name: VALINE / type: ligand / ID: 93 / Number of copies: 1 / Formula: VAL
• Molecular weight: Theoretical: 117.146 Da

Chemical component information

ChemComp-VAL:
VALINE

Macromolecule #94: FE2/S2 (INORGANIC) CLUSTER

• Macromolecule: Name: FE2/S2 (INORGANIC) CLUSTER / type: ligand / ID: 94 / Number of copies: 3 / Formula: FES
• Molecular weight: Theoretical: 175.82 Da

Chemical component information

ChemComp-FES:
FE2/S2 (INORGANIC) CLUSTER

Macromolecule #95: NICOTINAMIDE-ADENINE-DINUCLEOTIDE

• Macromolecule: Name: NICOTINAMIDE-ADENINE-DINUCLEOTIDE / type: ligand / ID: 95 / Number of copies: 1 / Formula: NAD
• Molecular weight: Theoretical: 663.425 Da

Chemical component information

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

Macromolecule #96: ZINC ION

• Macromolecule: Name: ZINC ION / type: ligand / ID: 96 / Number of copies: 3 / Formula: ZN
• Molecular weight: Theoretical: 65.409 Da

Macromolecule #97: ADENOSINE-5'-TRIPHOSPHATE

• Macromolecule: Name: ADENOSINE-5'-TRIPHOSPHATE / type: ligand / ID: 97 / Number of copies: 1 / Formula: ATP
• Molecular weight: Theoretical: 507.181 Da

Chemical component information

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

Macromolecule #98: GUANOSINE-5'-DIPHOSPHATE

• Macromolecule: Name: GUANOSINE-5'-DIPHOSPHATE / type: ligand / ID: 98 / Number of copies: 1 / Formula: GDP
• Molecular weight: Theoretical: 443.201 Da

Chemical component information

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

Experimental details

Structure determination

• Method: cryo EM
• Processing: single particle reconstruction
• Aggregation state: particle

Sample preparation

• Buffer: pH: 7.4 / Details: Methods part of the manuscript
• Vitrification: Cryogen name: ETHANE / Chamber humidity: 100 % / Chamber temperature: 277 K / Instrument: HOMEMADE PLUNGER / Details: Manual blotting & plunge-freezing.

Electron microscopy

• Microscope: TFS KRIOS
• Image recording: Film or detector model: FEI FALCON III (4k x 4k) / Detector mode: INTEGRATING / Number real images: 54447 / Average electron dose: 35.0 e/Ų
• Electron beam: Acceleration voltage: 300 kV / Electron source: FIELD EMISSION GUN
• Electron optics: Illumination mode: FLOOD BEAM / Imaging mode: BRIGHT FIELD / Cs: 0.01 mm / Nominal defocus max: 2.0 µm / Nominal defocus min: 0.2 µm / Nominal magnification: 59000
• Sample stage: Specimen holder model: FEI TITAN KRIOS AUTOGRID HOLDER
• Experimental equipment: Model: Titan Krios / Image courtesy: FEI Company

Image processing

• Particle selection: Number selected: 2068820
• CTF correction: Software - Name: Gctf / Type: PHASE FLIPPING AND AMPLITUDE CORRECTION

Startup model

Type of model: EMDB MAP
EMDB ID:

13981

• Final reconstruction: Resolution.type: BY AUTHOR / Resolution: 3.6 Å / Resolution method: FSC 0.143 CUT-OFF / Software - Name: RELION (ver. 5) / Number images used: 23725
• Initial angle assignment: Type: MAXIMUM LIKELIHOOD / Software - Name: RELION (ver. 5)
• Final angle assignment: Type: MAXIMUM LIKELIHOOD / Software - Name: RELION (ver. 5)
• Final 3D classification: Software - Name: RELION (ver. 5)

Atomic model buiding 1

Initial model

PDB ID:

7qi5

Chain - Source name: PDB / Chain - Initial model type: experimental model

• Refinement: Space: REAL / Protocol: FLEXIBLE FIT / Target criteria: RSCC

Output model

PDB-9s7d:
Structure of human mitochondrial COX1-translating ribosome nascent chain-OXA1L/MITRAC complex in open state (open COX1-mtRNC-OXA1L/MITRAC)