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Yorodumi- ChemComp-RX8: 1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-met... -
+Open data
-Basic information
Entry | Database: PDB chemical components / ID: RX8 | ||||
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Name | Name: Synonyms: R848; Resiquimod Wikipedia | Wikipedia - Resiquimod: Resiquimod is a drug that acts as an immune response modifier, and has antiviral and antitumour activity. It is used as a topical gel in the treatment of skin lesions such as those caused by the herpes simplex virus and cutaneous T cell lymphoma, and as an adjuvant to increase the effectiveness of vaccines... | Comment | antivirus*YM | |
-Chemical information
Composition | Formula: C17H22N4O2 / Number of atoms: 45 / Formula weight: 314.382 / Formal charge: 0 | ||||||
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Others | Type: NON-POLYMER / PDB classification: HETAIN / Three letter code: RX8 / Ideal coordinates details: Corina / Model coordinates PDB-ID: 3W3L | ||||||
History |
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External links | UniChem / BindingDB / ChEBI / ChEMBL / ChemicalBook / CompTox / DrugBank / GtoPharmacology / HMDB / Nikkaji / PubChem / PubChem_TPharma / SureChEMBL / ZINC / ChemSpider / Wikipedia search / Google search |
-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Details
-SMILES
ACDLabs 12.01 | CACTVS 3.370 | OpenEye OEToolkits 1.7.6 | |
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-SMILES CANONICAL
CACTVS 3.370 | OpenEye OEToolkits 1.7.6 | |
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-InChI
InChI 1.03 |
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-InChIKey
InChI 1.03 |
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-SYSTEMATIC NAME
ACDLabs 12.01 | OpenEye OEToolkits 1.7.6 | |
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-PDB entries
Showing all 5 items
PDB-3w3l:
Crystal structure of human TLR8 in complex with Resiquimod (R848) crystal form 1
PDB-3w3m:
Crystal structure of human TLR8 in complex with Resiquimod (R848) crystal form 2
PDB-3w3n:
Crystal structure of human TLR8 in complex with Resiquimod (R848) crystal form 3
PDB-5ans:
Potent and selective inhibitors of MTH1 probe its role in cancer cell survival
PDB-5gmh:
Crystal structure of monkey TLR7 in complex with R848