+Open data
-Basic information
Entry | Database: PDB chemical components / ID: J01 | ||||
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Name | Name: ( Synonyms: CLAVULANIC ACID Wikipedia | Wikipedia - Clavulanic acid: Clavulanic acid is a β-lactam drug that functions as a mechanism-based β-lactamase inhibitor. While not effective by itself as an antibiotic, when combined with penicillin-group antibiotics, it can overcome antibiotic resistance in bacteria that secrete β-lactamase, which otherwise inactivates most penicillins.
| In its most common preparations, potassium clavulanate (clavulanic acid as a salt of potassium) is combined with: .....Comment | antibiotic, inhibitor*YM | |
-Chemical information
Composition | Formula: C8H9NO5 / Number of atoms: 23 / Formula weight: 199.161 / Formal charge: 0 | ||||||
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Others | Type: NON-POLYMER / PDB classification: HETAIN / Three letter code: J01 / Ideal coordinates details: OpenEye/OEToolkits V1.4.2 | ||||||
History |
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External links | UniChem / BindingDB / Brenda / ChEBI / ChEMBL / ChemicalBook / CompTox / DailyMed / DrugBank / GtoPharmacology / HMDB / KEGG_Ligand / Metabolights / NMRShiftDB / Nikkaji / PubChem / PubChem_TPharma / SureChEMBL / ZINC / ChemSpider / Wikipedia search / Google search |
-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Details
-SMILES
ACDLabs 10.04 | CACTVS 3.341 | OpenEye OEToolkits 1.5.0 | |
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-SMILES CANONICAL
CACTVS 3.341 | OpenEye OEToolkits 1.5.0 | |
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-InChI
InChI 1.03 |
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-InChIKey
InChI 1.03 |
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-SYSTEMATIC NAME
ACDLabs 10.04 | (OpenEye OEToolkits 1.5.0 | ( | |
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-PDB entries
Showing all 6 items
PDB-2jap:
Clavulanic Acid Dehydrogenase: Structural and Biochemical Analysis of the Final Step in the Biosynthesis of the beta-Lactamase Inhibitor Clavulanic acid
PDB-2xf3:
Structural and mechanistic studies on a cephalosporin esterase from the clavulanic acid biosynthesis pathway
PDB-2xfs:
Structural and mechanistic studies on a cephalosporin esterase from the clavulanic acid biosynthesis pathway
PDB-2xh9:
Structural and mechanistic studies on a cephalosporin esterase from the clavulanic acid biosynthesis pathway
PDB-6nvu:
Crystal structure of TLA-1 extended spectrum Beta-lactamase in complex with Clavulanic Acid
PDB-6pq8:
Crystal structure of TLA-1 S70G extended spectrum Beta-lactamase in complex with clavulanic acid