登録情報 データベース : PDB / ID : 7dqa 構造の表示 ダウンロードとリンクタイトル Cryo-EM structure of SARS-CoV2 RBD-ACE2 complex 要素Angiotensin-converting enzyme 2 Spike glycoprotein 詳細キーワード VIRAL PROTEIN / SARS-CoV2 / Spike protein / ACE2機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
positive regulation of amino acid transport / angiotensin-converting enzyme 2 / positive regulation of L-proline import across plasma membrane / angiotensin-mediated drinking behavior / 加水分解酵素; プロテアーゼ; ペプチド結合加水分解酵素; 金属プロテアーゼ / regulation of systemic arterial blood pressure by renin-angiotensin / positive regulation of gap junction assembly / tryptophan transport / regulation of cardiac conduction / regulation of vasoconstriction ... positive regulation of amino acid transport / angiotensin-converting enzyme 2 / positive regulation of L-proline import across plasma membrane / angiotensin-mediated drinking behavior / 加水分解酵素; プロテアーゼ; ペプチド結合加水分解酵素; 金属プロテアーゼ / regulation of systemic arterial blood pressure by renin-angiotensin / positive regulation of gap junction assembly / tryptophan transport / regulation of cardiac conduction / regulation of vasoconstriction / peptidyl-dipeptidase activity / maternal process involved in female pregnancy / transporter activator activity / Metabolism of Angiotensinogen to Angiotensins / carboxypeptidase activity / angiotensin maturation / Attachment and Entry / receptor-mediated endocytosis of virus by host cell / metallocarboxypeptidase activity / viral life cycle / positive regulation of cardiac muscle contraction / regulation of cytokine production / blood vessel diameter maintenance / negative regulation of smooth muscle cell proliferation / brush border membrane / negative regulation of ERK1 and ERK2 cascade / positive regulation of reactive oxygen species metabolic process / metallopeptidase activity / endocytic vesicle membrane / regulation of cell population proliferation / virus receptor activity / regulation of inflammatory response / endopeptidase activity / Maturation of spike protein / Translation of Structural Proteins / Virion Assembly and Release / host cell surface / host extracellular space / viral translation / Potential therapeutics for SARS / symbiont-mediated-mediated suppression of host tetherin activity / Induction of Cell-Cell Fusion / structural constituent of virion / membrane fusion / entry receptor-mediated virion attachment to host cell / Attachment and Entry / host cell endoplasmic reticulum-Golgi intermediate compartment membrane / positive regulation of viral entry into host cell / receptor-mediated virion attachment to host cell / host cell surface receptor binding / cilium / symbiont-mediated suppression of host innate immune response / apical plasma membrane / receptor ligand activity / membrane raft / endocytosis involved in viral entry into host cell / endoplasmic reticulum lumen / symbiont entry into host cell / fusion of virus membrane with host plasma membrane / fusion of virus membrane with host endosome membrane / viral envelope / virion attachment to host cell / SARS-CoV-2 activates/modulates innate and adaptive immune responses / host cell plasma membrane / virion membrane / cell surface / negative regulation of transcription by RNA polymerase II / extracellular space / extracellular exosome / extracellular region / zinc ion binding / identical protein binding / membrane / plasma membrane 類似検索 - 分子機能 Collectrin domain / Renal amino acid transporter / Collectrin-like domain profile. / Peptidase M2, peptidyl-dipeptidase A / Angiotensin-converting enzyme / Peptidase family M2 domain profile. / Neutral zinc metallopeptidases, zinc-binding region signature. / Spike (S) protein S1 subunit, receptor-binding domain, SARS-CoV-2 / Spike (S) protein S1 subunit, N-terminal domain, SARS-CoV-like / Coronavirus spike glycoprotein S1, C-terminal ... Collectrin domain / Renal amino acid transporter / Collectrin-like domain profile. / Peptidase M2, peptidyl-dipeptidase A / Angiotensin-converting enzyme / Peptidase family M2 domain profile. / Neutral zinc metallopeptidases, zinc-binding region signature. / Spike (S) protein S1 subunit, receptor-binding domain, SARS-CoV-2 / Spike (S) protein S1 subunit, N-terminal domain, SARS-CoV-like / Coronavirus spike glycoprotein S1, C-terminal / Coronavirus spike glycoprotein S1, C-terminal / Spike glycoprotein, betacoronavirus / Spike glycoprotein, N-terminal domain superfamily / Betacoronavirus spike (S) glycoprotein S1 subunit N-terminal (NTD) domain profile. / Betacoronavirus spike (S) glycoprotein S1 subunit C-terminal (CTD) domain profile. / Spike (S) protein S1 subunit, receptor-binding domain, betacoronavirus / Spike S1 subunit, receptor binding domain superfamily, betacoronavirus / Betacoronavirus spike glycoprotein S1, receptor binding / Spike glycoprotein S1, N-terminal domain, betacoronavirus-like / Betacoronavirus-like spike glycoprotein S1, N-terminal / Spike glycoprotein S2, coronavirus, heptad repeat 1 / Spike glycoprotein S2, coronavirus, heptad repeat 2 / Coronavirus spike (S) glycoprotein S2 subunit heptad repeat 1 (HR1) region profile. / Coronavirus spike (S) glycoprotein S2 subunit heptad repeat 2 (HR2) region profile. / Spike glycoprotein S2 superfamily, coronavirus / Spike glycoprotein S2, coronavirus / Coronavirus spike glycoprotein S2 類似検索 - ドメイン・相同性 Spike glycoprotein / Angiotensin-converting enzyme 2 類似検索 - 構成要素生物種 Homo sapiens (ヒト) Severe acute respiratory syndrome coronavirus 2 (ウイルス)手法 電子顕微鏡法 / 単粒子再構成法 / クライオ電子顕微鏡法 / 解像度 : 2.8 Å 詳細データ登録者 Wang, J. / Lan, J. / Wang, X.Q. / Wang, H.W. 引用ジャーナル : Biophys Rep / 年 : 2022タイトル : Reduced graphene oxide membrane as supporting film for high-resolution cryo-EM著者 : Liu, N. / Zheng, L.M. / Xu, J. / Wang, J. / Hu, C.X. / Lan, J. / Zhang, X. / Zhang, J.C. / Xu, K. / Cheng, H. / Yang, Z. / Gao, X. / Wang, X.Q. / Peng, H.L. / Chen, Y.N. / Wang, H.W. 履歴 登録 2020年12月22日 登録サイト : PDBJ / 処理サイト : PDBJ改定 1.0 2021年12月29日 Provider : repository / タイプ : Initial release改定 1.0 2021年12月29日 Data content type : EM metadata / Data content type : EM metadata / Provider : repository / タイプ : Initial release改定 1.0 2021年12月29日 Data content type : Image / Data content type : Image / Provider : repository / タイプ : Initial release改定 1.0 2021年12月29日 Data content type : Primary map / Data content type : Primary map / Provider : repository / タイプ : Initial release改定 1.0 2021年12月29日 Data content type : Image / Data content type : Image / Provider : repository / タイプ : Initial release改定 1.0 2021年12月29日 Data content type : Primary map / Data content type : Primary map / Provider : repository / タイプ : Initial release改定 1.0 2021年12月29日 Data content type : Image / Data content type : Image / Provider : repository / タイプ : Initial release改定 1.0 2021年12月29日 Data content type : Primary map / Data content type : Primary map / Provider : repository / タイプ : Initial release改定 1.1 2022年7月13日 Group : Database references / カテゴリ : citationItem : _citation.country / _citation.journal_abbrev ... _citation.country / _citation.journal_abbrev / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.year 改定 1.2 2024年10月23日 Group : Data collection / Structure summaryカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / em_admin / pdbx_entry_details / pdbx_modification_feature Item : _em_admin.last_update / _pdbx_entry_details.has_protein_modification改定 1.3 2025年7月2日 Group : Data collection / カテゴリ : em_admin / em_software / Item : _em_admin.last_update / _em_software.name改定 1.1 2025年7月2日 Data content type : EM metadata / Data content type : EM metadata / EM metadata / Group : Data processing / Experimental summary / Data content type : EM metadata / EM metadata / カテゴリ : em_admin / em_software / Data content type : EM metadata / EM metadata / Item : _em_admin.last_update / _em_software.name
すべて表示 表示を減らす