Entry Database : PDB / ID : 7yl1 Structure visualization Downloads & linksTitle Crystal structure of JNK3 in complex with a fragment molecule ComponentsMitogen-activated protein kinase 10 Details Keywords TRANSFERASE / JNK3 fragment catalytic domainFunction / homology Function and homology informationFunction Domain/homology Component
JUN kinase activity / Activation of the AP-1 family of transcription factors / Fc-epsilon receptor signaling pathway / MAP kinase kinase activity / response to light stimulus / mitogen-activated protein kinase / JNK cascade / JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 / regulation of circadian rhythm / FCERI mediated MAPK activation ... JUN kinase activity / Activation of the AP-1 family of transcription factors / Fc-epsilon receptor signaling pathway / MAP kinase kinase activity / response to light stimulus / mitogen-activated protein kinase / JNK cascade / JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 / regulation of circadian rhythm / FCERI mediated MAPK activation / cellular senescence / rhythmic process / Oxidative Stress Induced Senescence / protein phosphorylation / protein serine kinase activity / signal transduction / mitochondrion / nucleoplasm / ATP binding / nucleus / plasma membrane / cytoplasm / cytosol Similarity search - Function Mitogen-activated protein (MAP) kinase, JNK / : / Mitogen-activated protein (MAP) kinase, conserved site / MAP kinase signature. / Serine/threonine-protein kinase, active site / Serine/Threonine protein kinases active-site signature. / Serine/Threonine protein kinases, catalytic domain / Protein kinase domain / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily Similarity search - Domain/homologyBiological species Homo sapiens (human)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 2.48 Å DetailsAuthors Ahn, H.-C. / Duong, M.T.H. Funding support Korea, Republic Of, 2items Details Hide detailsOrganization Grant number Country National Research Foundation (NRF, Korea) NRF-2018R1D1A1B07050975 Korea, Republic Of National Research Foundation (NRF, Korea) 2021R1F1A1063558 Korea, Republic Of
CitationJournal : To Be Published Title : Crystal structure of JNK3 in complex with a fragment moleculeAuthors : Ahn, H.-C. / Duong, M.T.H. History Deposition Jul 25, 2022 Deposition site : PDBJ / Processing site : PDBJRevision 1.0 Jul 26, 2023 Provider : repository / Type : Initial releaseRevision 1.1 May 29, 2024 Group : Data collection / Category : chem_comp_atom / chem_comp_bond
Show all Show less