登録情報 データベース : PDB / ID : 6gxe 構造の表示 ダウンロードとリンクタイトル Carbonic Anhydrase CAIX mimic in complex with inhibitor JS14 要素Carbonic anhydrase 2 詳細 キーワード LYASE / Carbonic Anhydrase / CAII mutant to CAIX mimic / CA Inhibitor機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
positive regulation of cellular pH reduction / positive regulation of dipeptide transmembrane transport / regulation of monoatomic anion transport / secretion / cyanamide hydratase / cyanamide hydratase activity / arylesterase activity / regulation of chloride transport / Reversible hydration of carbon dioxide / angiotensin-activated signaling pathway ... positive regulation of cellular pH reduction / positive regulation of dipeptide transmembrane transport / regulation of monoatomic anion transport / secretion / cyanamide hydratase / cyanamide hydratase activity / arylesterase activity / regulation of chloride transport / Reversible hydration of carbon dioxide / angiotensin-activated signaling pathway / positive regulation of synaptic transmission, GABAergic / morphogenesis of an epithelium / regulation of intracellular pH / carbonic anhydrase / carbonate dehydratase activity / carbon dioxide transport / Erythrocytes take up oxygen and release carbon dioxide / Erythrocytes take up carbon dioxide and release oxygen / neuron cellular homeostasis / one-carbon metabolic process / apical part of cell / myelin sheath / zinc ion binding / extracellular exosome / plasma membrane / cytosol / cytoplasm 類似検索 - 分子機能 Carbonic Anhydrase II / Alpha carbonic anhydrase / Carbonic anhydrase, alpha-class, conserved site / Alpha-carbonic anhydrases signature. / Carbonic anhydrase, alpha-class / Alpha carbonic anhydrase domain / Alpha carbonic anhydrase domain superfamily / Eukaryotic-type carbonic anhydrase / Alpha-carbonic anhydrases profile. / Eukaryotic-type carbonic anhydrase ... Carbonic Anhydrase II / Alpha carbonic anhydrase / Carbonic anhydrase, alpha-class, conserved site / Alpha-carbonic anhydrases signature. / Carbonic anhydrase, alpha-class / Alpha carbonic anhydrase domain / Alpha carbonic anhydrase domain superfamily / Eukaryotic-type carbonic anhydrase / Alpha-carbonic anhydrases profile. / Eukaryotic-type carbonic anhydrase / Roll / Alpha Beta 類似検索 - ドメイン・相同性生物種 Homo sapiens (ヒト)手法 X線回折 / 分子置換 / 解像度 : 1.3 Å 詳細データ登録者 Brynda, J. / Rezacova, P. / Pospisilova, K. 資金援助 チェコ, 1件 詳細 詳細を隠す組織 認可番号 国 Czech Science Foundation GA15-05677S チェコ
引用ジャーナル : Acs Omega / 年 : 2019タイトル : Inhibitor-Polymer Conjugates as a Versatile Tool for Detection and Visualization of Cancer-Associated Carbonic Anhydrase Isoforms著者 : Pospisilova, K. / Knedlik, T. / Sacha, P. / Kostka, L. / Schimer, J. / Brynda, J. / Kral, V. / Cigler, P. / Navratil, V. / Etrych, T. / Subr, V. / Kugler, M. / Fabry, M. / Rezacova, P. / Konvalinka, J. 履歴 登録 2018年6月27日 登録サイト : PDBE / 処理サイト : PDBE改定 1.0 2019年5月8日 Provider : repository / タイプ : Initial release改定 1.1 2019年12月25日 Group : Data collection / カテゴリ : reflns_shell / Item : _reflns_shell.percent_possible_all改定 1.2 2024年5月15日 Group : Data collection / Database references / カテゴリ : chem_comp_atom / chem_comp_bond / database_2Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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