Entry Database : PDB / ID : 5bru Structure visualization Downloads & linksTitle Catalytic Improvement of an Artificial Metalloenzyme by Computational Design ComponentsCarbonic anhydrase 2 Details Keywords OXIDOREDUCTASE / artificial metalloenzymeFunction / homology Function and homology informationFunction Domain/homology Component
positive regulation of cellular pH reduction / positive regulation of dipeptide transmembrane transport / regulation of monoatomic anion transport / secretion / cyanamide hydratase / cyanamide hydratase activity / arylesterase activity / regulation of chloride transport / Reversible hydration of carbon dioxide / angiotensin-activated signaling pathway ... positive regulation of cellular pH reduction / positive regulation of dipeptide transmembrane transport / regulation of monoatomic anion transport / secretion / cyanamide hydratase / cyanamide hydratase activity / arylesterase activity / regulation of chloride transport / Reversible hydration of carbon dioxide / angiotensin-activated signaling pathway / positive regulation of synaptic transmission, GABAergic / morphogenesis of an epithelium / regulation of intracellular pH / carbonic anhydrase / carbonate dehydratase activity / carbon dioxide transport / Erythrocytes take up oxygen and release carbon dioxide / Erythrocytes take up carbon dioxide and release oxygen / neuron cellular homeostasis / one-carbon metabolic process / apical part of cell / myelin sheath / zinc ion binding / extracellular exosome / plasma membrane / cytoplasm / cytosol Similarity search - Function Carbonic Anhydrase II / Alpha carbonic anhydrase / Carbonic anhydrase, alpha-class, conserved site / Alpha-carbonic anhydrases signature. / Carbonic anhydrase, alpha-class / Alpha carbonic anhydrase domain / Alpha carbonic anhydrase domain superfamily / Eukaryotic-type carbonic anhydrase / Alpha-carbonic anhydrases profile. / Eukaryotic-type carbonic anhydrase ... Carbonic Anhydrase II / Alpha carbonic anhydrase / Carbonic anhydrase, alpha-class, conserved site / Alpha-carbonic anhydrases signature. / Carbonic anhydrase, alpha-class / Alpha carbonic anhydrase domain / Alpha carbonic anhydrase domain superfamily / Eukaryotic-type carbonic anhydrase / Alpha-carbonic anhydrases profile. / Eukaryotic-type carbonic anhydrase / Roll / Alpha Beta Similarity search - Domain/homologyBiological species Homo sapiens (human)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / molecular replacement / Resolution : 1.6 Å DetailsAuthors Heinisch, T. / Pellizzoni, M. / Duerrenberger, M. / Tinberg, C.E. / Koehler, V. / Klehr, J. / Haeussinger, D. / Baker, D. / Ward, T.R. CitationJournal : J.Am.Chem.Soc. / Year : 2015Title : Improving the Catalytic Performance of an Artificial Metalloenzyme by Computational Design.Authors : Heinisch, T. / Pellizzoni, M. / Durrenberger, M. / Tinberg, C.E. / Kohler, V. / Klehr, J. / Haussinger, D. / Baker, D. / Ward, T.R. History Deposition Jun 1, 2015 Deposition site : RCSB / Processing site : PDBERevision 1.0 Jun 24, 2015 Provider : repository / Type : Initial releaseRevision 1.1 Aug 12, 2015 Group : Database referencesRevision 1.2 Aug 26, 2015 Group : Database referencesRevision 1.3 Jan 10, 2024 Group : Data collection / Database references / Refinement descriptionCategory : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / diffrn_radiation_wavelength / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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