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TitleHuman GGPPS Bound to Selective Inhibitor CML-07-119 in the Exposed Binding Site Conformation
Journal, issue, pagesTo Be Published
Publish dateNov 20, 2025 (structure data deposition date)
AuthorsFerens FG / Tsantrizos YS / Lemieux MJ
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.27 Å
Structure data

73981

9zbb

EMDB-73981: Human GGPPS Bound to Selective Inhibitor CML-07-119 in theExposed Binding Site Conformation
PDB-9zbb: Human GGPPS Bound to Selective Inhibitor CML-07-119 in the Exposed Binding Site Conformation
Method: EM (single particle) / Resolution: 2.27 Å

Chemicals

PDB-1c1e:
CRYSTAL STRUCTURE OF A DIELS-ALDERASE CATALYTIC ANTIBODY 1E9 IN COMPLEX WITH ITS HAPTEN

ChemComp-MG:
Unknown entry

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/INHIBITOR / Inhibitor / complex / isoprenoid / synthesis / TRANSFERASE / TRANSFERASE-INHIBITOR complex

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