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TitleCrystal Structure of a ternary complex of Saccharomyces cerevisiae Sec14 with a small molecule inhibitor and phosphatidylcholine
Journal, issue, pagesTo Be Published
Publish dateOct 23, 2025 (structure data deposition date)
AuthorsSingh, P.K. / Green, S.M. / Krieger, I. / Sacchettini, J. / Igumenova, T.I. / Bankaitis, V.A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.25 Å
Structure data

PDB-9yv3:
Crystal Structure of a ternary complex of Saccharomyces cerevisiae Sec14 with a small molecule inhibitor and phosphatidylcholine
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

Chemicals

ChemComp-POV:
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate / phospholipid*YM

ChemComp-IUO:
(4-chloranyl-3-nitro-phenyl)-[4-(2-fluorophenyl)piperazin-1-yl]methanone

ChemComp-HOH:
WATER

Source
  • saccharomyces cerevisiae (brewer's yeast)
KeywordsLIPID BINDING PROTEIN / Sec14 protein / PITP family / SIGNALING PROTEIN

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