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Structure paper

TitleCryo-EM structure of VRC49.01 in complex with HIV-1 Env BG505 DS-SOSIP trimer
Journal, issue, pagesTo be published
Publish dateSep 23, 2025 (structure data deposition date)
AuthorsGorman J / Kwong PD
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.34 - 3.81 Å
Structure data

72839

9ydw

EMDB-72839, PDB-9ydw:
Cryo-EM structure of single-bound FDG antibody VRC49.01 in complex with HIV-1 Env BG505 DS-SOSIP trimer
Method: EM (single particle) / Resolution: 3.34 Å

72855

9yem

EMDB-72855, PDB-9yem:
Cryo-EM structure of triple-bound FDG antibody VRC49.01 in complex with HIV-1 Env BG505 DS-SOSIP trimer
Method: EM (single particle) / Resolution: 3.81 Å

72857

9yeo

EMDB-72857, PDB-9yeo:
Cryo-EM structure of double-bound FDG antibody VRC49.01 in complex with HIV-1 Env BG505 DS-SOSIP trimer
Method: EM (single particle) / Resolution: 3.64 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • homo sapiens (human)
  • human immunodeficiency virus 1
  • human immunodeficiency virus
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / HIV-1 / SOSIP / Vaccine / VIRAL PROTEIN-IMMUNE SYSTEM complex / FDG / V3 / glycan / IMMUNE SYSTEM

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