EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	The S180R Human Germline Variant of DNA Polymerase beta Is a Low Fidelity Enzyme with Reduced Flexibility of the Fingers Domain.
ジャーナル・号・ページ	Biochemistry, Year 2026
掲載日	2025年8月29日 (構造データの登録日)
著者	Sawyer, D.L. / Eckenroth, B.E. / Chavira, C. / Alnajjar, K. / Hanley, J.P. / Dragon, J.A. / Doublie, S. / Sweasy, J.B.
リンク	Biochemistry / PubMed:41524291
手法	X線回折
解像度	1.55 - 2.15 Å
構造データ	PDB-9y15: WT human DNA polymerase beta, Binary complex templating dA 手法: X-RAY DIFFRACTION / 解像度: 1.85 Å PDB-9y16: WT human DNA polymerase beta, Binary complex templating dG 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-9y17: WT human DNA polymerase beta, Binary complex templating dT 手法: X-RAY DIFFRACTION / 解像度: 1.85 Å PDB-9y18: WT human DNA polymerase beta, Binary complex templating dC 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-9y19: WT human DNA polymerase beta, Ternary complex dA:dUmpNpp 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-9y1a: WT human DNA polymerase beta, Ternary complex dT:dAmpCpp 手法: X-RAY DIFFRACTION / 解像度: 1.93 Å PDB-9y1b: WT human DNA polymerase beta, Ternary complex dC:dGmpCpp 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-9y1c: WT human DNA polymerase beta, Ternary complex dG:dCmpCpp 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-9y1d: S180R human DNA polymerase beta, Binary complex templating dA 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å PDB-9y1e: S180R human DNA polymerase beta, Binary complex templating dG 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-9y1f: S180R human DNA polymerase beta, Binary complex templating dT 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-9y1g: S180R human DNA polymerase beta, Binary complex templating dC 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-9y1h: S180R human DNA polymerase beta, Ternary complex dA:dUmpNpp 手法: X-RAY DIFFRACTION / 解像度: 1.96 Å PDB-9y1i: S180R human DNA polymerase beta, Ternary complex dG:dCmpCpp 手法: X-RAY DIFFRACTION / 解像度: 2.15 Å PDB-9y1j: S180R human DNA polymerase beta, Ternary complex dT:dAmpCpp 手法: X-RAY DIFFRACTION / 解像度: 1.55 Å PDB-9y1k: S180R human DNA polymerase beta, Ternary complex dC:dGmpCpp 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å
化合物	ChemComp-NA: Unknown entry / ナトリウムカチオン ChemComp-CL: Unknown entry / クロリド ChemComp-HOH: WATER ChemComp-MG: Unknown entry / マグネシウムジカチオン ChemComp-DUP: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE / α,β-イミノ-dUTP ChemComp-F2A: 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]adenosine ChemComp-1GC: 2'-deoxy-5'-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]guanosine ChemComp-XC5: 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine
由来	homo sapiens (ヒト) synthetic construct (人工物)
キーワード	REPLICATION / HYDROLASE/DNA / polymerase / HYDROLASE-DNA complex