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| Title | Molecular mechanism of pore formation by Plasmodium Perforin-like Protein 2 |
|---|---|
| Journal, issue, pages | Nat Commun, Year 2026 |
| Publish date | Oct 27, 2025 (structure data deposition date) |
Authors | Zhang Y / Zhong L / Song Y / Guo M / Ren K / Yang T / Huang Y / Sirotkin I / Yi G / Jiao F ...Zhang Y / Zhong L / Song Y / Guo M / Ren K / Yang T / Huang Y / Sirotkin I / Yi G / Jiao F / Zhang P / Gilbert RJC / Ni T / Yu X |
External links | Nat Commun / Search PubMed |
| Methods | EM (subtomogram averaging) / EM (single particle) |
| Resolution | 3.9 - 28.27 Å |
| Structure data | ![]() EMDB-66758: Plasmodium vivax Perforin-like protein 2 K735C/E771C mutant(PvPLP2 K735C/E771C) prepore on membrane by cryoET subtomogram averaging ![]() EMDB-66759: Plasmodium vivax Perforin-like protein 2 pore on membrane by cryoET subtomogram averaging EMDB-66760, PDB-9xda: EMDB-66761, PDB-9xdb: |
| Source |
|
Keywords | TOXIN / Plasmodium; Perforin-like protein; PvPLP2 |
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