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TitleStructural Basis for the lanthipeptide biosynthesis mechanism of a dimeric Class III lanthipeptide synthetase
Journal, issue, pagesTo Be Published
Publish dateAug 30, 2025 (structure data deposition date)
AuthorsZhang H / Luo M
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.35 - 4.25 Å
Structure data

66012

9wj0

EMDB-66012, PDB-9wj0:
Cryo-EM structure of ClassIII Lanthipeptide modification enzyme TherKC with chain A bounded to substrate TherA and ATPrS.
Method: EM (single particle) / Resolution: 3.35 Å

66127

9wop

EMDB-66127, PDB-9wop:
Cryo-EM structure of ClassIII Lanthipeptide modification enzyme TherKC with chain A bounded to substrate TherA and ATPrS.
Method: EM (single particle) / Resolution: 4.25 Å

Chemicals

ChemComp-AGS:
PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER / ATP-gamma-S, energy-carrying molecule analogue*YM

Source
  • thermoactinomyces sp. dsm 45892 (bacteria)
KeywordsPEPTIDE BINDING PROTEIN / Lanthipeptide modification enzyme

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