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TitleSwitching the strict substrate specificities of the beta-ketoacyl-acyl carrier protein synthases, FabH and BioZ.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 122, Page e2509301122-e2509301122, Year 2025
Publish dateAug 15, 2024 (structure data deposition date)
AuthorsHang, X. / Zhang, L. / Huang, Y. / Hu, Y. / Zeng, Q. / Cronan, J.E. / Bi, H.
External linksProc. Natl. Acad. Sci. USA / PubMed:41183203
MethodsX-ray diffraction
Resolution2.15 - 2.5 Å
Structure data

PDB-9j6e:
Crystal structure of BioZ from Agrobacterium tumefaciens in complex with galutaryl-CoA
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

PDB-9w96:
Crystal structure of BioZ C115S from Agrobacterium tumefaciens in complex with galutaryl-CoA
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-COA:
COENZYME A

ChemComp-HOH:
WATER

ChemComp-GRA:
glutaryl-coenzyme A

Source
  • agrobacterium fabrum (strain c58 / atcc 33970) (bacteria)
  • agrobacterium fabrum str. c58 (bacteria)
KeywordsBIOSYNTHETIC PROTEIN / Biotin synthesis / BioZ

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