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TitleStructural insights into allosteric activation of pyruvate kinase R by mitapivat and novel agonists
Journal, issue, pagesTo Be Published
Publish dateJul 19, 2025 (structure data deposition date)
AuthorsMa HY / Su ZM
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.48 Å
Structure data

65437

9vxp

EMDB-65437, PDB-9vxp:
Cryo-EM structure of human Pyruvate kinase R (PK-R)
Method: EM (single particle) / Resolution: 2.48 Å

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Pyruvate kinase PKLR / Cryo-EM / PKLR / PKD / Red cell/liver pyruvate kinase

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