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Structure paper

TitleStructural basis for RNA synthesis and inhibition of the orthobunyavirus polymerase
Journal, issue, pagesTo Be Published
Publish dateJul 8, 2025 (structure data deposition date)
AuthorsTang J / Deng Z
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.0 - 3.55 Å
Structure data

65295

9vs3

EMDB-65295, PDB-9vs3:
Apo structure of Ebinur lake virus polymerase
Method: EM (single particle) / Resolution: 3.55 Å

65296

9vs4

EMDB-65296, PDB-9vs4:
Structure of Ebinur lake virus polymerase complexed with suramin
Method: EM (single particle) / Resolution: 3.0 Å

65297

9vs5

EMDB-65297, PDB-9vs5:
Structure of Ebinur lake virus polymerase at the elongation state
Method: EM (single particle) / Resolution: 3.31 Å

Chemicals

ChemComp-SVR:
8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON / medication*YM

Source
  • ebinur lake virus
  • Pipistrellus nathusii (Nathusius's pipistrelle)
  • synthetic construct (others)
KeywordsVIRAL PROTEIN / polymerase / suramin / VIRAL PROTEIN/RNA / elongation complex / L protein / RNA / VIRAL PROTEIN-RNA complex

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