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TitleSynthesis of L-Tryptophan Analogs by Ancestral L-Tryptophan Synthase beta-Subunit with High Organic Solvent Tolerance
Journal, issue, pagesChemcatchem, Year 2025
Publish dateJun 14, 2025 (structure data deposition date)
AuthorsOhata, M. / Fujita, S. / Uchida, K. / Kobayashi, S. / Chisuga, T. / Nakano, S.
External linksChemcatchem / Search PubMed
MethodsX-ray diffraction
Resolution1.7 - 2.2 Å
Structure data

PDB-9vgk:
Ancestral L-tryptophan synthase beta-subunit 1 complex with Trp-PLP
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-9vgl:
Ancestral L-tryptophan synthase beta-subunit 1
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-VB4:
(E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-D-tryptophan

ChemComp-HOH:
WATER

Source
  • synthetic construct (others)
KeywordsBIOSYNTHETIC PROTEIN / L-tryptophan synthase beta-subunit / L-tryptophan synthase

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