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TitleStructural insights into type-I and type-II Lamassu antiphage systems.
Journal, issue, pagesNat. Chem. Biol., Year 2026
Publish dateMay 13, 2025 (structure data deposition date)
AuthorsLi, M. / Zhao, X. / Li, D. / Xiong, W. / Gao, Z. / Huang, L. / An, L. / Gao, Y. / Li, S. / Feng, Y. ...Li, M. / Zhao, X. / Li, D. / Xiong, W. / Gao, Z. / Huang, L. / An, L. / Gao, Y. / Li, S. / Feng, Y. / Zhang, K. / Zhang, Y.
External linksNat. Chem. Biol. / PubMed:41482579
MethodsEM (single particle)
Resolution3.03 - 4.07 Å
Structure data

PDB-9ux7:
CryoEM Structure of LmuAB-DNA complex
Method: ELECTRON MICROSCOPY / Resolution: 3.73 Å

PDB-9ux8:
CryoEM Structure of LmuAB Apo State
Method: ELECTRON MICROSCOPY / Resolution: 3.71 Å

PDB-9uxh:
type II Lamassu, LmuACB with DNA
Method: ELECTRON MICROSCOPY / Resolution: 3.03 Å

PDB-9uxi:
type II Lamassu, LmuA tetramer
Method: ELECTRON MICROSCOPY / Resolution: 3.64 Å

PDB-9uxk:
type II Lamassu, LmuACB from Vibrio cholerae O1 El
Method: ELECTRON MICROSCOPY / Resolution: 3.54 Å

PDB-9uxl:
type II Lamassu, LmuACB from Vibrio cholerae O1 El
Method: ELECTRON MICROSCOPY / Resolution: 4.07 Å

Source
  • bacillus sp. nio-1130 (bacteria)
  • synthetic construct (others)
  • vibrio cholerae (bacteria)
KeywordsIMMUNE SYSTEM / complex / anti-phage system / DNA BINDING PROTEIN / endonuclease; Structural maintenance of chromosomes (SMC) proteins; DNA BINDING PROTEIN

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