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TitleMedin drives Abeta40 to adopt Abeta42-like fibril polymorphs in vitro
Journal, issue, pagesTo Be Published
Publish dateJan 26, 2026 (structure data deposition date)
AuthorsPradhan B / Kumar ST / Wagner J / Gallardo R / Zorzini V / Orlando G / Vleeschouwer MD / Madine J / Louros N / Neher J ...Pradhan B / Kumar ST / Wagner J / Gallardo R / Zorzini V / Orlando G / Vleeschouwer MD / Madine J / Louros N / Neher J / Schymkowitz J / Rousseau F
External linksSearch PubMed
MethodsEM (helical sym.)
Resolution2.7 Å
Structure data

56480

9u02

EMDB-56480, PDB-9u02:
Medin fibril generated from the heterotypic interaction of Abeta40 and Medin.
Method: EM (helical sym.) / Resolution: 2.7 Å

Source
  • homo sapiens (human)
KeywordsPROTEIN FIBRIL / Medin / Amyloid / Aggregation / MFGE8 / Neurodegeneration

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