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TitleCrystal structure of Brugia malayi DAF-12 ligand binding domain in complex with a coactivator peptide and delta4-dafachronic acid
Journal, issue, pagesTo Be Published
Publish dateDec 11, 2025 (structure data deposition date)
AuthorsMallet, M. / le Maire, A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.7 Å
Structure data

PDB-9tlx:
Crystal structure of Brugia malayi DAF-12 ligand binding domain in complex with a coactivator peptide and delta4-dafachronic acid
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-DL4:
(14beta,17alpha,25R)-3-oxocholest-4-en-26-oic acid

ChemComp-CIT:
CITRIC ACID

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • brugia malayi (agent of lymphatic filariasis)
  • homo sapiens (human)
KeywordsDNA BINDING PROTEIN / Nuclear Hormone Receptor / Transcriptional coregulators / Transcription factor / Ligand binding domain

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