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TitleEngineering the ADDomer Nanoparticle Vaccine Scaffold for Improved Assembly and Enhanced Stability.
Journal, issue, pagesAcs Synth Biol, Year 2026
Publish dateOct 4, 2025 (structure data deposition date)
AuthorsBalchin, G. / Kabasakal, B.V. / Strofaldi, A. / Hall, S. / Fletcher, C. / Buzas, D. / Bufton, J.C. / Yadav, S.K.N. / Shen, D. / Garzoni, F. ...Balchin, G. / Kabasakal, B.V. / Strofaldi, A. / Hall, S. / Fletcher, C. / Buzas, D. / Bufton, J.C. / Yadav, S.K.N. / Shen, D. / Garzoni, F. / Bunzel, H.A. / McManus, J.J. / Schaffitzel, C. / Berger, I.
External linksAcs Synth Biol / PubMed:41840818
MethodsEM (single particle)
Resolution2.2 - 2.61 Å
Structure data

PDB-9swa:
Adenovirus dodecahedron
Method: ELECTRON MICROSCOPY / Resolution: 2.2 Å

PDB-9sy5:
Engineering the ADDomer Nanoparticle Vaccine Scaffold for Improved Assembly and Enhanced Stability.
Method: ELECTRON MICROSCOPY / Resolution: 2.61 Å

Chemicals

ChemComp-K:
Unknown entry

Source
  • chimpanzee adenovirus y25
KeywordsVIRUS LIKE PARTICLE / adenovirus / vaccine / dodecahedron / Nanoparticle / Disulphide bond / Thermostable.

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