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TitleThe mutational landscape of STING-induced immunity
Journal, issue, pagesNature, Year 2026
Publish dateOct 7, 2025 (structure data deposition date)
AuthorsZhang, B. / Xu, P. / Meng, Y. / Gallay, L. / Lestelle, F. / Morel, H. / Fremond, M.L. / Correia, B.E. / Ablasser, A.
External linksNature / Search PubMed
MethodsEM (single particle)
Resolution2.86 - 3.38 Å
Structure data

PDB-9swm:
Stimulator of interferon genes protein
Method: ELECTRON MICROSCOPY / Resolution: 3.38 Å

PDB-9swq:
Stimulator of interferon genes protein mutant - I165H
Method: ELECTRON MICROSCOPY / Resolution: 3.31 Å

PDB-9swr:
Stimulator of interferon genes protein mutant - W119K M120K
Method: ELECTRON MICROSCOPY / Resolution: 2.86 Å

PDB-9sws:
Stimulator of interferon genes protein mutant - D319K D320K
Method: ELECTRON MICROSCOPY / Resolution: 3.04 Å

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / STING / Innate Immunity

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