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TitleIn Vitro Co-Aggregation with medin Induces an Abeta42-Like Polymorph of Abeta40 Fibrils.
Journal, issue, pagesTo Be Published
Publish dateJun 11, 2025 (structure data deposition date)
AuthorsPradhan B / Kumar ST / Wagner J / Gallardo R / Orlando G / Vleeschouwer MD / Madine J / Louros N / Neher J / Schymkowitz J / Rousseau F
External linksSearch PubMed
MethodsEM (helical sym.)
Resolution2.63 - 3.1 Å
Structure data

54006

9riv

EMDB-54006, PDB-9riv:
Population B fibril generated from the Heterotypic interaction of Abeta40 and Medin.
Method: EM (helical sym.) / Resolution: 2.63 Å

54007

9riw

EMDB-54007, PDB-9riw:
Population A fibril generated from the Heterotypic interaction of Abeta40 and Medin.
Method: EM (helical sym.) / Resolution: 3.1 Å

Source
  • homo sapiens (human)
KeywordsPROTEIN FIBRIL / Amyloid Beta 40 / Aggregation / Neurodegeneration / Medin

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