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-Structure paper
| Title | Mechanistic insights into complement classical pathway C3 convertase based on cryo-EM structures |
|---|---|
| Journal, issue, pages | To Be Published |
| Publish date | Mar 18, 2025 (structure data deposition date) |
Authors | De la O Becerra KI / Brondijk THC / Serna Martin I / Gros P |
External links | Search PubMed |
| Methods | EM (single particle) |
| Resolution | 3.5 - 4.3 Å |
| Structure data | EMDB-53198, PDB-9qj4: EMDB-53199, PDB-9qj5: EMDB-53217, PDB-9qk2: EMDB-53288, PDB-9qpy: |
| Chemicals | ![]() ChemComp-NAG: ![]() ChemComp-MG: |
| Source |
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Keywords | IMMUNE SYSTEM / Proconvertase / Complement / classical pathway / C4b2 / C3 convertase / Complement classical pathway / convertase-substrate complex / C3 substrate / convertase complex / Enzyme |
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