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| Title | Conformational Basis of Functionally Selective Allosteric Modulation of the Angiotensin II type 1 Receptor by Small Molecules |
|---|---|
| Journal, issue, pages | To Be Published |
| Publish date | Aug 12, 2025 (structure data deposition date) |
Authors | Liu S / Xiao P / Elgeti M / Fine EJ / Lucero EY / Vestergaard M / Wang J / Jyothidasan A / Angus L / Qu C ...Liu S / Xiao P / Elgeti M / Fine EJ / Lucero EY / Vestergaard M / Wang J / Jyothidasan A / Angus L / Qu C / Olsen E / Mazis G / Madsen JK / Suomivuori C-M / Kim J / Pakharukova N / Rahman R / Kereliuk SM / Koch W / Strachan RT / Staus DP / Masoudi A / Hubbell WL / Kahsai AW / Dror RO / Rockman HA / Sun J-P / Ahn S / Lefkowitz RJ |
External links | Search PubMed |
| Methods | EM (single particle) |
| Resolution | 3.02 Å |
| Structure data | EMDB-72097, PDB-9q0f: |
| Chemicals | ![]() ChemComp-CLR: ![]() PDB-1cnf: |
| Source |
|
Keywords | SIGNALING PROTEIN / Angiotensin II Type 1 Receptor / AT1R / G protein-coupled receptor / GPCR |
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