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TitleEnv-antibody coevolution identifies B cell priming as the principal bottleneck to HIV-1 V2 apex broadly neutralizing antibody development
Journal, issue, pagesTo Be Published
Publish dateMay 13, 2025 (structure data deposition date)
AuthorsHabib R / Roark RS / Kwong PD / Shaw GM
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.6 Å
Structure data

70613

9omg

EMDB-70613: Cryo-EM structure of rhesus antibody V033-Int1 in complex with HIV Env trimer Q23.17 MD39
PDB-9omg: Cryo-EM structure of rhesus antibody V033-a.I1 in complex with HIV Env trimer Q23.17 MD39
Method: EM (single particle) / Resolution: 3.6 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • macaca mulatta (Rhesus monkey)
  • homo sapiens (human)
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / Neutralizing antibody / HIV-1 V2 apex / SHIV-elicited / VIRAL PROTEIN / VIRAL PROTEIN-IMMUNE SYSTEM complex

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