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Structure paper

TitleComposite map of six VRC35 Fabs and three MEDI8852 Fabs bound to influenza H3N2 Victoria 2011 hemagglutinin
Journal, issue, pagesTo Be Published
Publish dateMay 13, 2025 (structure data deposition date)
AuthorsCheng J / Cale EM / Longo N / Sutton MS / Lei H / Huang R / Morton AJ / Lang ZC / Morano NC / Roark RS ...Cheng J / Cale EM / Longo N / Sutton MS / Lei H / Huang R / Morton AJ / Lang ZC / Morano NC / Roark RS / Becker JE / Tsybovsky Y / Li N / Zhang B / Du H / Rubin S / Shapiro L / Pierson TC / Doria-Rose NA / Kwong PD / Zhou T
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.4 Å
Structure data

70607

9om5

EMDB-70607, PDB-9om5:
Composite map of six VRC35 Fabs and three MEDI8852 Fabs bound to influenza H3N2 Victoria 2011 hemagglutinin
Method: EM (single particle) / Resolution: 3.4 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-MAN:
alpha-D-mannopyranose

Source
  • homo sapiens (human)
  • influenza a virus
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / broadly neutralizing antibody / cryo-EM / hemagglutinin / high mannose / homotypic interactions / influenza A virus / multimeric recognition / N-linked glycan / ANTIVIRAL PROTEIN / VIRAL PROTEIN / VIRAL PROTEIN-IMMUNE SYSTEM complex

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