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Structure paper

TitlePseudouridine residues as substrates for serum ribonucleases.
Journal, issue, pagesRna, Vol. 31, Page 1542-1556, Year 2025
Publish dateFeb 17, 2025 (structure data deposition date)
AuthorsGutierrez, C.S. / Silkenath, B. / Kojasoy, V. / Pich, J.A. / Lim, D.C. / Raines, R.T.
External linksRna / PubMed:40835455
MethodsX-ray diffraction
Resolution1.7 - 1.83 Å
Structure data

PDB-9ncs:
RNase A in complex with Uridine Vanadate and decavanadates
Method: X-RAY DIFFRACTION / Resolution: 1.83 Å

PDB-9o4v:
RNase A in complex with Pseudouridine Vanadate and decavanadates
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-9o5b:
RNase A in complex with N1-Methylpseudouridine Vanadate and decavanadates
Method: X-RAY DIFFRACTION / Resolution: 1.71 Å

Chemicals

ChemComp-DVT:
DECAVANADATE

ChemComp-URI:
URIDINE

ChemComp-VVO:
oxovanadium(2+)

ChemComp-HOH:
WATER

ChemComp-FJF:
5-[(2~{S},3~{R},4~{S},5~{R})-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]-1~{H}-pyrimidine-2,4-dione

ChemComp-8IZ:
5-[(2S,3R,4S,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]-1-methyl-pyrimidine-2,4-dione

Source
  • bos taurus (domestic cattle)
KeywordsHYDROLASE / Ribonuclease / RNA / Uridine Vanadate / decavanadate / pseudouridine / pseudouridine vanadate / N1-Methylpseudouridine Vanadate

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