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Structure paper

TitleDeazaguanylation is a nucleobase-protein conjugation required for type IV CBASS immunity.
Journal, issue, pagesScience, Vol. 389, Page 1347-1352, Year 2025
Publish dateMar 18, 2025 (structure data deposition date)
AuthorsWassarman, D.R. / Pfaff, P. / Paulo, J.A. / Gygi, S.P. / Shokat, K.M. / Kranzusch, P.J.
External linksScience / PubMed:40997174
MethodsX-ray diffraction
Resolution2.15 - 2.43 Å
Structure data

PDB-9ntn:
Structure of Cap10-CdnD complex containing NDG modification
Method: X-RAY DIFFRACTION / Resolution: 2.43 Å

PDB-9nto:
Structure of Cap9-CdnD complex containing NDG modification
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

Chemicals

ChemComp-COA:
COENZYME A

ChemComp-2KA:
2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carboxylic acid

ChemComp-HOH:
WATER

ChemComp-AMP:
ADENOSINE MONOPHOSPHATE / AMP*YM

ChemComp-ZN:
Unknown entry

ChemComp-ADN:
ADENOSINE

Source
  • hyphomicrobiales (bacteria)
KeywordsANTIVIRAL PROTEIN / CD-NTase / QueC / CBASS

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