Title | Cryo-EM structures of a pentameric ligand-gated ion channel in liposomes |
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Journal, issue, pages | Elife, Year 2025 |
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Publish date | Feb 22, 2025 (structure data deposition date) |
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Authors | Dalal V / Tan BK / Xu H / Cheng WW |
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External links | Elife / Search PubMed |
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Methods | EM (single particle) |
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Resolution | 3.4 - 4.3 Å |
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Structure data | EMDB-49383, PDB-9ngf: ELIC facing ECD outwards in liposomes with 2:1:1 POPC:POPE:POPG Method: EM (single particle) / Resolution: 3.4 Å EMDB-49384, PDB-9ngg: ELIC facing ECD inwards in liposomes with 2:1:1 POPC:POPE:POPG Method: EM (single particle) / Resolution: 3.6 Å EMDB-49385, PDB-9ngi: ELIC5 with propylamine facing ECD inwards in liposomes with 2:1:1 POPC:POPE:POPG Method: EM (single particle) / Resolution: 4.3 Å EMDB-49390, PDB-9ngq: ELIC state 1 with propylamine facing ECD outwards in liposomes with 2:1:1 POPC:POPE:POPG Method: EM (single particle) / Resolution: 3.8 Å EMDB-49391, PDB-9ngr: ELIC state 2 with propylamine facing ECD outwards in liposomes with 2:1:1 POPC:POPE:POPG Method: EM (single particle) / Resolution: 3.8 Å EMDB-49392, PDB-9ngs: ELIC with propylamine facing ECD inwards in liposomes with 2:1:1 POPC:POPE:POPG Method: EM (single particle) / Resolution: 4.2 Å EMDB-49400, PDB-9nh4: ELIC with propylamine in spNW25 nanodiscs with 2:1:1 POPC:POPE:POPG Method: EM (single particle) / Resolution: 3.9 Å |
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Chemicals | |
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Source | dickeya dadantii (bacteria)
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Keywords | MEMBRANE PROTEIN / ELIC / ion channel / pLGIC / Structural Protein / TRANSPORT PROTEIN |
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