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TitleInterplay between C alpha Methylation and C alpha Stereochemistry in the Folding Energetics of a Helix-Rich Miniprotein.
Journal, issue, pagesChembiochem, Vol. 26, Page e202401022-e202401022, Year 2025
Publish dateDec 9, 2024 (structure data deposition date)
AuthorsHarmon, T.W. / Lin, Y. / Sutton, R.T. / Osborne, S.W.J. / Seth Horne, W.
External linksChembiochem / PubMed:39791987
MethodsNMR (solution)
Structure data

PDB-9mf7:
Backbone alpha-Methylation in the Villin Headpiece Miniprotein: Prototype HP35
Method: SOLUTION NMR

PDB-9mf8:
Backbone alpha-Methylation in the Villin Headpiece Miniprotein: HP35 with Aib at Position 15
Method: SOLUTION NMR

PDB-9mf9:
Backbone alpha-Methylation in the Villin Headpiece Miniprotein: HP35 with Calpha-methyl-Ser at Position 15
Method: SOLUTION NMR

PDB-9mfa:
Backbone alpha-Methylation in the Villin Headpiece Miniprotein: HP35 with Aib at Position 30
Method: SOLUTION NMR

PDB-9mfb:
Backbone alpha-Methylation in the Villin Headpiece Miniprotein: HP35 with Calpha-methyl-Lys at Position 30
Method: SOLUTION NMR

Source
  • gallus gallus (chicken)
KeywordsSTRUCTURAL PROTEIN / Miniprotein / heterogeneous backbone / proteomimetic / Villin-1 headpiece: Met12Nle / Lys30alphaMeLys

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