| タイトル | Structural determinants of broadly neutralizing human antibodies binding to morphological dengue virus variants. |
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| ジャーナル・号・ページ | To Be Published |
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| 掲載日 | 2025年3月5日 (構造データの登録日) |
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著者 | Chatterjee AC / Roy A / Srinivasan S / Charles S / Lubow J / Goo L / Mangala Prasad V |
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リンク | PubMedで検索 |
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| 手法 | EM (単粒子) / EM (らせん対称) |
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| 解像度 | 3.85 - 38.5 Å |
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| 構造データ | EMDB-63643, PDB-9m5h: D14.F25.S02 Fab complexed to DENV2-US/BID/V594/2006 virus (5f-3f map) 手法: EM (単粒子) / 解像度: 4.09 Å EMDB-63759, PDB-9mav: Cryo-EM structure of Dengue virus serotype2 US/BID-V594/2006 strain bound with J9 fab. 手法: EM (単粒子) / 解像度: 3.85 Å EMDB-63762, PDB-9maz: Helical Reconstruction of DENV2 US/BID-V594/2006 tubular particles bound with J9 fab 手法: EM (らせん対称) / 解像度: 38.5 Å EMDB-63763, PDB-9mb0: Cryo-EM structure of Dengue virus serotype2 THSTI/TRC/01 strain bound with J9 fab 手法: EM (単粒子) / 解像度: 7.21 Å EMDB-63764, PDB-9mb1: Helical Reconstruction of DENV2 THSTI/TRC/01 tubular particles bound with J9 fab 手法: EM (らせん対称) / 解像度: 14.41 Å EMDB-63809, PDB-9u34: Helical Reconstruction of DENV2 US/BID-V594/2006 tubular particles bound with D14.F25.S02 fab 手法: EM (らせん対称) / 解像度: 14.7 Å EMDB-63810, PDB-9u35: Helical Reconstruction of DENV2 THSTI/TRC/01 tubular particles bound with D14.F25.S02 fab 手法: EM (らせん対称) / 解像度: 17.37 Å EMDB-63811, PDB-9u36: Cryo-EM structure of Dengue virus serotype2 THSTI/TRC/01 strain bound with D14.F25.SO2 fab 手法: EM (単粒子) / 解像度: 19.08 Å EMDB-63812, PDB-9u37: D14.F25.S02 IgG complexed to DENV2-US/BID/V594/2006 virus 手法: EM (単粒子) / 解像度: 7.65 Å EMDB-63813, PDB-9u38: D14.F25.S02 Fab complexed to DENV2-US/BID/V594/2006 virus-3f-2f Fab map 手法: EM (単粒子) / 解像度: 6.48 Å |
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| 化合物 | ChemComp-NAG: 2-acetamido-2-deoxy-beta-D-glucopyranose
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| 由来 | homo sapiens (ヒト) dengue virus type 2 (デング熱ウイルス)
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キーワード | VIRUS / Dengue virus / flavivirus / broadly neutralizing antibody / fab-virus complex / E-protein / VIRAL PROTEIN/IMMUNE SYSTEM / neutralizing antibody / helical / VIRAL PROTEIN-IMMUNE SYSTEM complex / Antibody binding / neutralization / neutralizing antibody binding |
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