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Structure paper

TitleMolecular interactions between piperine and peroxisome proliferator-activated receptor gamma ligand-binding domain revealed using co-crystallization studies.
Journal, issue, pagesActa Crystallogr. ,Sect. F, Vol. 81, Page 201-206, Year 2025
Publish dateDec 19, 2024 (structure data deposition date)
AuthorsEgawa, D. / Ishida, H. / Katakawa, K.
External linksActa Crystallogr. ,Sect. F / PubMed:40172924
MethodsX-ray diffraction
Resolution2.36 Å
Structure data

PDB-9l3t:
PPARgamma Ligand binding domain in complex with piperine
Method: X-RAY DIFFRACTION / Resolution: 2.36 Å

Chemicals

ChemComp-AYR:
(2E,4E)-5-(2H-1,3-benzodioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / PPARgamma / piperine / nuclear receptor / nutural product / Peroxisome Proliferator-Activated Receptor / transcription factor / ligand binding domain / NUCLEAR PROTEIN

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