EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Mechanistic insights into the ATP-mediated and species-dependent inhibition of TrpRS by chuangxinmycin.
ジャーナル・号・ページ	Rsc Chem Biol, Vol. 6, Page 1079-1088, Year 2025
掲載日	2024年12月5日 (構造データの登録日)
著者	Ren, Y. / Wang, S. / Liu, W. / Wang, J. / Fang, P.
リンク	Rsc Chem Biol / PubMed:40406164
手法	X線回折
解像度	1.92 - 3.04 Å
構造データ	PDB-9kvc: Crystal structure of tryptophanyl-tRNA synthetase from Staphylococcus aureus 手法: X-RAY DIFFRACTION / 解像度: 3.04 Å PDB-9kw0: Crystal structure of S. aureus tryptophanyl-tRNA synthetase complexed with tryptophan 手法: X-RAY DIFFRACTION / 解像度: 2.32 Å PDB-9kwh: Crystal structure of S. aureus tryptophanyl-tRNA synthetase complexed with chuangxinmycin 手法: X-RAY DIFFRACTION / 解像度: 2.38 Å PDB-9kww: Crystal structure of S. aureus tryptophanyl-tRNA synthetase complexed with 3-demethylchuangxinmycin 手法: X-RAY DIFFRACTION / 解像度: 2.12 Å PDB-9kxb: Crystal structure of S. aureus tryptophanyl-tRNA synthetase complexed with 3-methylchuangxinmycin 手法: X-RAY DIFFRACTION / 解像度: 2.21 Å PDB-9kxr: Crystal structure of E. coli tryptophanyl-tRNA synthetase complexed with chuangxinmycin and tryptophanyl-5'-AMP 手法: X-RAY DIFFRACTION / 解像度: 2.24 Å PDB-9ky3: Crystal structure of E. coli tryptophanyl-tRNA synthetase complexed with 3-demethylchuangxinmycin and tryptophanyl-5'-AMP 手法: X-RAY DIFFRACTION / 解像度: 2.25 Å PDB-9ky9: Crystal structure of E. coli tryptophanyl-tRNA synthetase complexed with 3-methylchuangxinmycin and tryptophanyl-5'-AMP 手法: X-RAY DIFFRACTION / 解像度: 2.19 Å PDB-9m1f: Crystal structure of E. coli tryptophanyl-tRNA synthetase complexed with chuangxinmycin and ATP in closed-closed state 手法: X-RAY DIFFRACTION / 解像度: 1.92 Å PDB-9m1g: Crystal structure of E. coli tryptophanyl-tRNA synthetase complexed with chuangxinmycin and ATP in open-closed state 手法: X-RAY DIFFRACTION / 解像度: 2.15 Å
化合物	ChemComp-PEG: DI(HYDROXYETHYL)ETHER ChemComp-TRP: TRYPTOPHAN ChemComp-HOH: WATER ChemComp-9E0: (5~{S},6~{R})-5-methyl-7-thia-2-azatricyclo[6.3.1.0^{4,12}]dodeca-1(12),3,8,10-tetraene-6-carboxylic acid PDB-1ehm: Unknown entry PDB-1ehn: CRYSTAL STRUCTURE OF CHITINASE A MUTANT E315Q COMPLEXED WITH OCTA-N-ACETYLCHITOOCTAOSE (NAG)8. ChemComp-SO4: SULFATE ION ChemComp-TYM: TRYPTOPHANYL-5'AMP ChemComp-ATP: ADENOSINE-5'-TRIPHOSPHATE / ATP, エネルギー貯蔵分子YM ChemComp-MG: Unknown entry ChemComp-GOL*: GLYCEROL
由来	staphylococcus aureus (黄色ブドウ球菌) escherichia coli (大腸菌)
キーワード	LIGASE / tryptophanyl-tRNA synthetase / aminoacyl-tRNA synthetase / antibiotic