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TitleStudies on Two Convergently Evolved Cysteate Synthases in Sulfonolipid Biosynthesis.
Journal, issue, pagesAcs Chem. Biol., Vol. 20, Page 2560-2573, Year 2025
Publish dateOct 17, 2024 (structure data deposition date)
AuthorsYang, S. / Wang, K. / Hu, Y. / Zhang, L. / Zhang, C. / Liu, Y. / Li, Z. / Jiang, L. / Han, Y. / Naowarojna, N. ...Yang, S. / Wang, K. / Hu, Y. / Zhang, L. / Zhang, C. / Liu, Y. / Li, Z. / Jiang, L. / Han, Y. / Naowarojna, N. / Wei, Y. / Zhang, Y.
External linksAcs Chem. Biol. / PubMed:41166334
MethodsX-ray diffraction
Resolution1.43 - 2.38 Å
Structure data

PDB-9k2p:
The crystal structure of CapA1 from Capnocytophaga ochracea
Method: X-RAY DIFFRACTION / Resolution: 2.08 Å

PDB-9k3c:
Crystal Structure of CapA2 from Alistipes finegoldii in complex with PLP cofactor
Method: X-RAY DIFFRACTION / Resolution: 2.38 Å

PDB-9k3o:
Crystal structure of CapA2 from Alistipes finegoldii in complex with OPS-PLP external aldimine
Method: X-RAY DIFFRACTION / Resolution: 1.43 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-CIT:
CITRIC ACID

ChemComp-PLP:
PYRIDOXAL-5'-PHOSPHATE

ChemComp-E1U:
(2S)-2-[(E)-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3-phosphonooxy-propanoic acid

Source
  • capnocytophaga ochracea dsm 7271 (bacteria)
  • alistipes finegoldii dsm 17242 (bacteria)
KeywordsBIOSYNTHETIC PROTEIN / PLP-dependent enzyme

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